5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide

C128H130Cl4N16O8S6 — CID 157075266

About 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide

5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 157075266) has the molecular formula C128H130Cl4N16O8S6 and a molecular weight of 2354.77 g/mol. Its IUPAC name is 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 157075266
• Molecular Formula: C128H130Cl4N16O8S6
• Molecular Weight: 2354.77 g/mol
• Exact Mass: 2350.73
• IUPAC Name: 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
• SMILES: COc1ccc(C2CC2NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2C2CC2)cc1.COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2-c2cnn(C)c2)cc1C.Cc1cc(C)c2c(-c3cnn(C)c3)c(C(=O)N3CCC(c4ccccc4)C3)sc2n1.Cc1nc2sc(C(=O)N3CCC(c4ccccc4)C3)c(C3CC3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NC3CCC3)c(-c3ccccc3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NC3CCC3)c(C)c2c(C)c1Cl
• InChI: InChI=1S/C24H24N4OS.C23H23ClN2O2S.C23H23ClN2OS.C23H24N4O2S.C20H19ClN2OS.C15H17ClN2OS/c1-15-11-16(2)26-23-20(15)21(19-12-25-27(3)13-19)22(30-23)24(29)28-10-9-18(14-28)17-7-5-4-6-8-17;1-11-18-19(14-4-5-14)21(29-23(18)25-12(2)20(11)24)22(27)26-17-10-16(17)13-6-8-15(28-3)9-7-13;1-13-18-19(16-8-9-16)21(28-22(18)25-14(2)20(13)24)23(27)26-11-10-17(12-26)15-6-4-3-5-7-15;1-13-9-16(6-7-18(13)29-5)10-24-22(28)21-20(17-11-25-27(4)12-17)19-14(2)8-15(3)26-23(19)30-21;1-11-15-16(13-7-4-3-5-8-13)18(19(24)23-14-9-6-10-14)25-20(15)22-12(2)17(11)21;1-7-11-8(2)13(14(19)18-10-5-4-6-10)20-15(11)17-9(3)12(7)16/h4-8,11-13,18H,9-10,14H2,1-3H3;6-9,14,16-17H,4-5,10H2,1-3H3,(H,26,27);3-7,16-17H,8-12H2,1-2H3;6-9,11-12H,10H2,1-5H3,(H,24,28);3-5,7-8,14H,6,9-10H2,1-2H3,(H,23,24);10H,4-6H2,1-3H3,(H,18,19)
• InChIKey: ACXAEEYSIRAXSE-UHFFFAOYSA-N
• XLogP: 30.99
• TPSA: 288.46 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 24
• Rotatable Bonds: 21
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2354.77
LogP ≤ 5	30.99
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CID 157075266) is 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is COc1ccc(C2CC2NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2C2CC2)cc1.COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2-c2cnn(C)c2)cc1C.Cc1cc(C)c2c(-c3cnn(C)c3)c(C(=O)N3CCC(c4ccccc4)C3)sc2n1.Cc1nc2sc(C(=O)N3CCC(c4ccccc4)C3)c(C3CC3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NC3CCC3)c(-c3ccccc3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NC3CCC3)c(C)c2c(C)c1Cl.

What is the InChIKey of 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is ACXAEEYSIRAXSE-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H24N4OS.C23H23ClN2O2S.C23H23ClN2OS.C23H24N4O2S.C20H19ClN2OS.C15H17ClN2OS/c1-15-11-16(2)26-23-20(15)21(19-12-25-27(3)13-19)22(30-23)24(29)28-10-9-18(14-28)17-7-5-4-6-8-17;1-11-18-19(14-4-5-14)21(29-23(18)25-12(2)20(11)24)22(27)26-17-10-16(17)13-6-8-15(28-3)9-7-13;1-13-18-19(16-8-9-16)21(28-22(18)25-14(2)20(13)24)23(27)26-11-10-17(12-26)15-6-4-3-5-7-15;1-13-9-16(6-7-18(13)29-5)10-24-22(28)21-20(17-11-25-27(4)12-17)19-14(2)8-15(3)26-23(19)30-21;1-11-15-16(13-7-4-3-5-8-13)18(19(24)23-14-9-6-10-14)25-20(15)22-12(2)17(11)21;1-7-11-8(2)13(14(19)18-10-5-4-6-10)20-15(11)17-9(3)12(7)16/h4-8,11-13,18H,9-10,14H2,1-3H3;6-9,14,16-17H,4-5,10H2,1-3H3,(H,26,27);3-7,16-17H,8-12H2,1-2H3;6-9,11-12H,10H2,1-5H3,(H,24,28);3-5,7-8,14H,6,9-10H2,1-2H3,(H,23,24);10H,4-6H2,1-3H3,(H,18,19).

What are the key properties of 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2354.77 g/mol, XLogP of 30.99, 21 rotatable bonds, 4 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-N-cyclobutyl-4,6-dimethyl-3-phenylthieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-cyclobutyl-3,4,6-trimethylthieno[2,3-b]pyridine-2-carboxamide;(5-chloro-3-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-phenylpyrrolidin-1-yl)methanone;5-chloro-3-cyclopropyl-N-[2-(4-methoxyphenyl)cyclopropyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;[4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]-(3-phenylpyrrolidin-1-yl)methanone;N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 157075266), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).