2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

C229H225F21N26O26 — CID 160503633

IUPAC2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
SMILESCCCCOc1ccc(-c2oc3nc(CCC(F)(F)F)c(-c4cccc(C(=O)NC(C)(C)C)c4)cc3c2C(=O)NC)cc1.CCNc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC(C)(C)C)c1.CCNc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC2(C(F)(F)F)CC2)c1.CNC(=O)c1c(-c2ccc(NCC(F)F)cc2)oc2nc(NCC(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(OCC(C)(F)F)cc2)oc2nc(CCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(Oc3cccc(C)c3)cc2)oc2nc(CCC(F)(F)F)c(-c3ccc(OC)c(C(=O)CC4(c5ncccn5)CC4)c3)cc12.CNC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)oc2nc(CCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12
InChIInChI=1S/C41H35F3N4O5.C35H32F3N3O4.C33H36F3N3O4.C32H32F5N3O4.C30H31F4N5O3.C29H27F3N4O3.C29H32N4O3/c1-24-6-4-7-28(20-24)52-27-11-8-25(9-12-27)36-35(37(50)45-2)31-22-29(32(48-38(31)53-36)14-15-41(42,43)44)26-10-13-34(51-3)30(21-26)33(49)23-40(16-17-40)39-46-18-5-19-47-39;1-34(2,3)41-31(42)23-10-8-9-22(19-23)26-20-27-29(32(43)39-4)30(45-33(27)40-28(26)17-18-35(36,37)38)21-13-15-25(16-14-21)44-24-11-6-5-7-12-24;1-6-7-17-42-23-13-11-20(12-14-23)28-27(30(41)37-5)25-19-24(26(38-31(25)43-28)15-16-33(34,35)36)21-9-8-10-22(18-21)29(40)39-32(2,3)4;1-30(2,3)40-27(41)20-8-6-7-19(15-20)22-16-23-25(28(42)38-5)26(44-29(23)39-24(22)13-14-32(35,36)37)18-9-11-21(12-10-18)43-17-31(4,33)34;1-30(2,3)39-27(40)18-7-5-6-17(12-18)20-13-21-24(28(41)35-4)25(42-29(21)38-26(20)37-15-23(33)34)16-8-10-19(11-9-16)36-14-22(31)32;1-4-34-24-20(18-6-5-7-19(14-18)25(37)36-28(12-13-28)29(30,31)32)15-21-22(26(38)33-3)23(39-27(21)35-24)17-10-8-16(2)9-11-17;1-7-31-25-21(19-9-8-10-20(15-19)26(34)33-29(3,4)5)16-22-23(27(35)30-6)24(36-28(22)32-25)18-13-11-17(2)12-14-18/h4-13,18-22H,14-17,23H2,1-3H3,(H,45,50);5-16,19-20H,17-18H2,1-4H3,(H,39,43)(H,41,42);8-14,18-19H,6-7,15-17H2,1-5H3,(H,37,41)(H,39,40);6-12,15-16H,13-14,17H2,1-5H3,(H,38,42)(H,40,41);5-13,22-23,36H,14-15H2,1-4H3,(H,35,41)(H,37,38)(H,39,40);5-11,14-15H,4,12-13H2,1-3H3,(H,33,38)(H,34,35)(H,36,37);8-16H,7H2,1-6H3,(H,30,35)(H,31,32)(H,33,34)
InChIKeyQSCPXWAJBMJJRF-UHFFFAOYSA-N
MW4156.43 g/mol
LogP51.14
Rot. Bonds62

About 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide (PubChem CID 160503633) has the molecular formula C229H225F21N26O26 and a molecular weight of 4156.43 g/mol. Its IUPAC name is 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide.

Molecular Properties

Compound Name2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
PubChem CID160503633
Molecular FormulaC229H225F21N26O26
Molecular Weight4156.43 g/mol
Exact Mass4153.67
IUPAC Name2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
SMILESCCCCOc1ccc(-c2oc3nc(CCC(F)(F)F)c(-c4cccc(C(=O)NC(C)(C)C)c4)cc3c2C(=O)NC)cc1.CCNc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC(C)(C)C)c1.CCNc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC2(C(F)(F)F)CC2)c1.CNC(=O)c1c(-c2ccc(NCC(F)F)cc2)oc2nc(NCC(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(OCC(C)(F)F)cc2)oc2nc(CCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(Oc3cccc(C)c3)cc2)oc2nc(CCC(F)(F)F)c(-c3ccc(OC)c(C(=O)CC4(c5ncccn5)CC4)c3)cc12.CNC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)oc2nc(CCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12
InChIInChI=1S/C41H35F3N4O5.C35H32F3N3O4.C33H36F3N3O4.C32H32F5N3O4.C30H31F4N5O3.C29H27F3N4O3.C29H32N4O3/c1-24-6-4-7-28(20-24)52-27-11-8-25(9-12-27)36-35(37(50)45-2)31-22-29(32(48-38(31)53-36)14-15-41(42,43)44)26-10-13-34(51-3)30(21-26)33(49)23-40(16-17-40)39-46-18-5-19-47-39;1-34(2,3)41-31(42)23-10-8-9-22(19-23)26-20-27-29(32(43)39-4)30(45-33(27)40-28(26)17-18-35(36,37)38)21-13-15-25(16-14-21)44-24-11-6-5-7-12-24;1-6-7-17-42-23-13-11-20(12-14-23)28-27(30(41)37-5)25-19-24(26(38-31(25)43-28)15-16-33(34,35)36)21-9-8-10-22(18-21)29(40)39-32(2,3)4;1-30(2,3)40-27(41)20-8-6-7-19(15-20)22-16-23-25(28(42)38-5)26(44-29(23)39-24(22)13-14-32(35,36)37)18-9-11-21(12-10-18)43-17-31(4,33)34;1-30(2,3)39-27(40)18-7-5-6-17(12-18)20-13-21-24(28(41)35-4)25(42-29(21)38-26(20)37-15-23(33)34)16-8-10-19(11-9-16)36-14-22(31)32;1-4-34-24-20(18-6-5-7-19(14-18)25(37)36-28(12-13-28)29(30,31)32)15-21-22(26(38)33-3)23(39-27(21)35-24)17-10-8-16(2)9-11-17;1-7-31-25-21(19-9-8-10-20(15-19)26(34)33-29(3,4)5)16-22-23(27(35)30-6)24(36-28(22)32-25)18-13-11-17(2)12-14-18/h4-13,18-22H,14-17,23H2,1-3H3,(H,45,50);5-16,19-20H,17-18H2,1-4H3,(H,39,43)(H,41,42);8-14,18-19H,6-7,15-17H2,1-5H3,(H,37,41)(H,39,40);6-12,15-16H,13-14,17H2,1-5H3,(H,38,42)(H,40,41);5-13,22-23,36H,14-15H2,1-4H3,(H,35,41)(H,37,38)(H,39,40);5-11,14-15H,4,12-13H2,1-3H3,(H,33,38)(H,34,35)(H,36,37);8-16H,7H2,1-6H3,(H,30,35)(H,31,32)(H,33,34)
InChIKeyQSCPXWAJBMJJRF-UHFFFAOYSA-N
XLogP51.14
TPSA697.63 Ų
H-Bond Donors17
H-Bond Acceptors39
Rotatable Bonds62
Heavy Atoms302
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004156.43
LogP ≤ 551.14
H-Bond Donors ≤ 517
H-Bond Acceptors ≤ 1039

Analyze 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide with MolForge

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Related Compounds

5-[3-(tert-butylcarbamoyl)phenyl]-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;3-methylphenol
CID 157390613
5-[3-(tert-butylcarbamoyl)phenyl]-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;2,2,2-trifluoroethanol
CID 161200005
5-[3-(tert-butylcarbamoyl)phenyl]-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;pyrrolidine
CID 162107160
5-[3-[(1-cyanocyclopropyl)carbamoyl]-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 118390579
5-[3-[2-(1-cyanocyclobutyl)acetyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 160618614
5-[3-(2,2-difluoropropylcarbamoyl)phenyl]-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 118896122
5-[5-[(1-cyanocyclopropyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 118390572
5-[3-(1-bicyclo[1.1.1]pentanylcarbamoyl)phenyl]-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 85470079
5-[3-[2-(1-cyanocyclobutyl)acetyl]-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[2-(1-cyanocyclopentyl)acetyl]-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3,4-dimethylpentanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[3-cyano-4-fluoro-3-(fluoromethyl)butanoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-4-fluoro-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 158742400
5-[3-[2-(1-bicyclo[1.1.1]pentanyl)acetyl]phenyl]-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 158825457
5-[3-[(1-aminocyclopentyl)carbamoyl]phenyl]-2-(4-fluorophenyl)-N-methyl-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 162570590
5-[3-[2-(1-cyanocyclopentyl)acetyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3,4-dimethylpentanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3,4-dimethylpentanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide
CID 158451212

Frequently Asked Questions

What is the IUPAC name of 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
The IUPAC name of 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide (CID 160503633) is 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide.
What is the SMILES notation for 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
The canonical SMILES for 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide is CCCCOc1ccc(-c2oc3nc(CCC(F)(F)F)c(-c4cccc(C(=O)NC(C)(C)C)c4)cc3c2C(=O)NC)cc1.CCNc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC(C)(C)C)c1.CCNc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC2(C(F)(F)F)CC2)c1.CNC(=O)c1c(-c2ccc(NCC(F)F)cc2)oc2nc(NCC(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(OCC(C)(F)F)cc2)oc2nc(CCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(Oc3cccc(C)c3)cc2)oc2nc(CCC(F)(F)F)c(-c3ccc(OC)c(C(=O)CC4(c5ncccn5)CC4)c3)cc12.CNC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)oc2nc(CCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C)c3)cc12.
What is the InChIKey of 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
The InChIKey is QSCPXWAJBMJJRF-UHFFFAOYSA-N. The full InChI is InChI=1S/C41H35F3N4O5.C35H32F3N3O4.C33H36F3N3O4.C32H32F5N3O4.C30H31F4N5O3.C29H27F3N4O3.C29H32N4O3/c1-24-6-4-7-28(20-24)52-27-11-8-25(9-12-27)36-35(37(50)45-2)31-22-29(32(48-38(31)53-36)14-15-41(42,43)44)26-10-13-34(51-3)30(21-26)33(49)23-40(16-17-40)39-46-18-5-19-47-39;1-34(2,3)41-31(42)23-10-8-9-22(19-23)26-20-27-29(32(43)39-4)30(45-33(27)40-28(26)17-18-35(36,37)38)21-13-15-25(16-14-21)44-24-11-6-5-7-12-24;1-6-7-17-42-23-13-11-20(12-14-23)28-27(30(41)37-5)25-19-24(26(38-31(25)43-28)15-16-33(34,35)36)21-9-8-10-22(18-21)29(40)39-32(2,3)4;1-30(2,3)40-27(41)20-8-6-7-19(15-20)22-16-23-25(28(42)38-5)26(44-29(23)39-24(22)13-14-32(35,36)37)18-9-11-21(12-10-18)43-17-31(4,33)34;1-30(2,3)39-27(40)18-7-5-6-17(12-18)20-13-21-24(28(41)35-4)25(42-29(21)38-26(20)37-15-23(33)34)16-8-10-19(11-9-16)36-14-22(31)32;1-4-34-24-20(18-6-5-7-19(14-18)25(37)36-28(12-13-28)29(30,31)32)15-21-22(26(38)33-3)23(39-27(21)35-24)17-10-8-16(2)9-11-17;1-7-31-25-21(19-9-8-10-20(15-19)26(34)33-29(3,4)5)16-22-23(27(35)30-6)24(36-28(22)32-25)18-13-11-17(2)12-14-18/h4-13,18-22H,14-17,23H2,1-3H3,(H,45,50);5-16,19-20H,17-18H2,1-4H3,(H,39,43)(H,41,42);8-14,18-19H,6-7,15-17H2,1-5H3,(H,37,41)(H,39,40);6-12,15-16H,13-14,17H2,1-5H3,(H,38,42)(H,40,41);5-13,22-23,36H,14-15H2,1-4H3,(H,35,41)(H,37,38)(H,39,40);5-11,14-15H,4,12-13H2,1-3H3,(H,33,38)(H,34,35)(H,36,37);8-16H,7H2,1-6H3,(H,30,35)(H,31,32)(H,33,34).
What are the key properties of 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide has a molecular weight of 4156.43 g/mol, XLogP of 51.14, 62 rotatable bonds, 17 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(4-butoxyphenyl)-5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(2,2-difluoroethylamino)-2-[4-(2,2-difluoroethylamino)phenyl]-N-methylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-2-[4-(2,2-difluoropropoxy)phenyl]-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(tert-butylcarbamoyl)phenyl]-N-methyl-2-(4-phenoxyphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;6-(ethylamino)-N-methyl-2-(4-methylphenyl)-5-[3-[[1-(trifluoromethyl)cyclopropyl]carbamoyl]phenyl]furo[2,3-b]pyridine-3-carboxamide;5-[4-methoxy-3-[2-(1-pyrimidin-2-ylcyclopropyl)acetyl]phenyl]-N-methyl-2-[4-(3-methylphenoxy)phenyl]-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide is sourced from PubChem (CID 160503633), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).