6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

C137H107F22N31O14S6 — CID 160506398

About 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (PubChem CID 160506398) has the molecular formula C137H107F22N31O14S6 and a molecular weight of 3021.92 g/mol. Its IUPAC name is 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 160506398
• Molecular Formula: C137H107F22N31O14S6
• Molecular Weight: 3021.92 g/mol
• Exact Mass: 3019.66
• IUPAC Name: 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• SMILES: Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(-c3ccccn3)c2cc1F.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(-c3cnccn3)c2cc1F.Cc1cc2c(C(N)=O)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(-c3ncccn3)c2cc1F.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccc(F)cc1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccc1.Cc1ccc2c(c1)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1cnccn1
• InChI: InChI=1S/C24H18F4N4O2S.C24H19F3N4O2S.C23H17F4N5O2S.C22H18F4N6O3S.C22H16F4N6O2S.C22H19F3N6O3S/c1-14-3-10-22-19(11-14)20(12-29)23(32(22)17-6-4-16(25)5-7-17)21-9-8-18(13-30-21)35(33,34)31-15(2)24(26,27)28;1-15-8-11-22-19(12-15)20(13-28)23(31(22)17-6-4-3-5-7-17)21-10-9-18(14-29-21)34(32,33)30-16(2)24(25,26)27;1-13-9-16-17(11-28)22(32(20(16)10-18(13)24)21-5-3-4-8-29-21)19-7-6-15(12-30-19)35(33,34)31-14(2)23(25,26)27;1-11-8-14-17(9-15(11)23)32(21-28-6-3-7-29-21)19(18(14)20(27)33)16-5-4-13(10-30-16)36(34,35)31-12(2)22(24,25)26;1-12-7-15-16(9-27)21(32(19(15)8-17(12)23)20-11-28-5-6-29-20)18-4-3-14(10-30-18)35(33,34)31-13(2)22(24,25)26;1-12-3-6-17-15(9-12)19(21(26)32)20(31(17)18-11-27-7-8-28-18)16-5-4-14(10-29-16)35(33,34)30-13(2)22(23,24)25/h3-11,13,15,31H,1-2H3;3-12,14,16,30H,1-2H3;3-10,12,14,31H,1-2H3;3-10,12,31H,1-2H3,(H2,27,33);3-8,10-11,13,31H,1-2H3;3-11,13,30H,1-2H3,(H2,26,32)/t15-;16-;14-;12-;2*13-/m000000/s1
• InChIKey: QSLSHZNYUUQMRA-WWMKUEBESA-N
• XLogP: 25.39
• TPSA: 655.51 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 37
• Rotatable Bonds: 32
• Heavy Atoms: 210
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3021.92
LogP ≤ 5	25.39
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (CID 160506398) is 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(-c3ccccn3)c2cc1F.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(-c3cnccn3)c2cc1F.Cc1cc2c(C(N)=O)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(-c3ncccn3)c2cc1F.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccc(F)cc1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccc1.Cc1ccc2c(c1)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1cnccn1.

What is the InChIKey of 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The InChIKey is QSLSHZNYUUQMRA-WWMKUEBESA-N. The full InChI is InChI=1S/C24H18F4N4O2S.C24H19F3N4O2S.C23H17F4N5O2S.C22H18F4N6O3S.C22H16F4N6O2S.C22H19F3N6O3S/c1-14-3-10-22-19(11-14)20(12-29)23(32(22)17-6-4-16(25)5-7-17)21-9-8-18(13-30-21)35(33,34)31-15(2)24(26,27)28;1-15-8-11-22-19(12-15)20(13-28)23(31(22)17-6-4-3-5-7-17)21-10-9-18(14-29-21)34(32,33)30-16(2)24(25,26)27;1-13-9-16-17(11-28)22(32(20(16)10-18(13)24)21-5-3-4-8-29-21)19-7-6-15(12-30-19)35(33,34)31-14(2)23(25,26)27;1-11-8-14-17(9-15(11)23)32(21-28-6-3-7-29-21)19(18(14)20(27)33)16-5-4-13(10-30-16)36(34,35)31-12(2)22(24,25)26;1-12-7-15-16(9-27)21(32(19(15)8-17(12)23)20-11-28-5-6-29-20)18-4-3-14(10-30-18)35(33,34)31-13(2)22(24,25)26;1-12-3-6-17-15(9-12)19(21(26)32)20(31(17)18-11-27-7-8-28-18)16-5-4-14(10-29-16)35(33,34)30-13(2)22(23,24)25/h3-11,13,15,31H,1-2H3;3-12,14,16,30H,1-2H3;3-10,12,14,31H,1-2H3;3-10,12,31H,1-2H3,(H2,27,33);3-8,10-11,13,31H,1-2H3;3-11,13,30H,1-2H3,(H2,26,32)/t15-;16-;14-;12-;2*13-/m000000/s1.

What are the key properties of 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide has a molecular weight of 3021.92 g/mol, XLogP of 25.39, 32 rotatable bonds, 8 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-6-fluoro-5-methyl-1-pyrazin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(4-fluorophenyl)-5-methylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-phenylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-fluoro-5-methyl-1-pyrimidin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 160506398), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).