2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide

C133H98F12N20O6S2 — CID 160530619

IUPAC2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide
SMILESCC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccnc4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccncc4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccncn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4nncs4)c3n2)c1.Cc1csc(NC(=O)c2cccc3ccc(-c4cccc(C(C)(F)F)c4)nc23)n1
InChIInChI=1S/3C23H17F2N3O.C22H16F2N4O.C22H17F2N3OS.C20H14F2N4OS/c1-23(24,25)17-7-2-6-16(13-17)20-11-10-15-5-3-9-19(21(15)28-20)22(29)27-18-8-4-12-26-14-18;1-23(24,25)17-6-2-5-16(14-17)20-9-8-15-4-3-7-19(21(15)28-20)22(29)27-18-10-12-26-13-11-18;1-23(24,25)17-8-4-7-16(14-17)19-12-11-15-6-5-9-18(21(15)27-19)22(29)28-20-10-2-3-13-26-20;1-22(23,24)16-6-2-5-15(12-16)18-9-8-14-4-3-7-17(20(14)27-18)21(29)28-19-10-11-25-13-26-19;1-13-12-29-21(25-13)27-20(28)17-8-4-5-14-9-10-18(26-19(14)17)15-6-3-7-16(11-15)22(2,23)24;1-20(21,22)14-6-2-5-13(10-14)16-9-8-12-4-3-7-15(17(12)24-16)18(27)25-19-26-23-11-28-19/h2-14H,1H3,(H,27,29);2-14H,1H3,(H,26,27,29);2-14H,1H3,(H,26,28,29);2-13H,1H3,(H,25,26,28,29);3-12H,1-2H3,(H,25,27,28);2-11H,1H3,(H,25,26,27)
InChIKeyQVMGRNHFKSBWGU-UHFFFAOYSA-N
MW2364.49 g/mol
LogP33.19
Rot. Bonds24

About 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide

2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide (PubChem CID 160530619) has the molecular formula C133H98F12N20O6S2 and a molecular weight of 2364.49 g/mol. Its IUPAC name is 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide.

Molecular Properties

Compound Name2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide
PubChem CID160530619
Molecular FormulaC133H98F12N20O6S2
Molecular Weight2364.49 g/mol
Exact Mass2362.72
IUPAC Name2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide
SMILESCC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccnc4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccncc4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccncn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4nncs4)c3n2)c1.Cc1csc(NC(=O)c2cccc3ccc(-c4cccc(C(C)(F)F)c4)nc23)n1
InChIInChI=1S/3C23H17F2N3O.C22H16F2N4O.C22H17F2N3OS.C20H14F2N4OS/c1-23(24,25)17-7-2-6-16(13-17)20-11-10-15-5-3-9-19(21(15)28-20)22(29)27-18-8-4-12-26-14-18;1-23(24,25)17-6-2-5-16(14-17)20-9-8-15-4-3-7-19(21(15)28-20)22(29)27-18-10-12-26-13-11-18;1-23(24,25)17-8-4-7-16(14-17)19-12-11-15-6-5-9-18(21(15)27-19)22(29)28-20-10-2-3-13-26-20;1-22(23,24)16-6-2-5-15(12-16)18-9-8-14-4-3-7-17(20(14)27-18)21(29)28-19-10-11-25-13-26-19;1-13-12-29-21(25-13)27-20(28)17-8-4-5-14-9-10-18(26-19(14)17)15-6-3-7-16(11-15)22(2,23)24;1-20(21,22)14-6-2-5-13(10-14)16-9-8-12-4-3-7-15(17(12)24-16)18(27)25-19-26-23-11-28-19/h2-14H,1H3,(H,27,29);2-14H,1H3,(H,26,27,29);2-14H,1H3,(H,26,28,29);2-13H,1H3,(H,25,26,28,29);3-12H,1-2H3,(H,25,27,28);2-11H,1H3,(H,25,26,27)
InChIKeyQVMGRNHFKSBWGU-UHFFFAOYSA-N
XLogP33.19
TPSA355.06 Ų
H-Bond Donors6
H-Bond Acceptors22
Rotatable Bonds24
Heavy Atoms173
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002364.49
LogP ≤ 533.19
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1022

Analyze 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide with MolForge

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Related Compounds

8-[5-[[3-[8-(2,6-difluorophenyl)-2-(pyridin-3-ylcarbamoyl)quinolin-4-yl]pyrrolidin-1-yl]methyl]-2-pyridinyl]-N-pyridin-3-yl-4-[1-[[6-[2-(1,3-thiazol-2-ylcarbamoyl)quinolin-8-yl]-3-pyridinyl]methyl]pyrrolidin-3-yl]quinoline-2-carboxamide
CID 90853181
[5-Fluoro-2-[4-[[1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-2-[[[5-(trifluoromethyl)pyrimidin-2-yl]amino]methyl]piperidin-3-yl]methyl]triazol-2-yl]phenyl]-[3-methyl-2-[[[5-(trifluoromethyl)-2-pyridinyl]amino]methyl]piperidin-1-yl]methanone
CID 123317930
N-[2-[4-[(2-ethyl-3,5-dimethylphenyl)carbamoyl]-2-oxo-6-[3-(trifluoromethyl)phenyl]-3H-pyrido[2,3-b]pyrazin-1-yl]ethyl]-N,4-dimethyl-2-[[1-[2-[2-[[1-methyl-2-oxo-6-[3-(trifluoromethyl)phenyl]-3H-pyrido[2,3-b]pyrazine-4-carbonyl]amino]-1,3-thiazol-5-yl]ethyl]-2-oxo-6-[3-(trifluoromethyl)phenyl]-3H-pyrido[2,3-b]pyrazine-4-carbonyl]amino]-1,3-thiazole-5-carboxamide
CID 123769635
4-(1,1-difluoroethyl)-N-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]pyridine-2-carboxamide;N-[3,4-difluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-6-methylpyridine-2-carboxamide;N-[3,4-difluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-1,3-thiazole-4-carboxamide;3-fluoro-N-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]-6-methylpyridine-2-carboxamide;N-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]-5-methylpyridine-2-carboxamide
CID 123938381
[5-fluoro-2-[4-[[(3R)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-2-[[[5-(trifluoromethyl)pyrimidin-2-yl]amino]methyl]piperidin-3-yl]methyl]triazol-2-yl]phenyl]-[3-methyl-2-[[[5-(trifluoromethyl)-2-pyridinyl]amino]methyl]piperidin-1-yl]methanone
CID 144902931
2-[4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-3-fluoroanilino]-8-(1-methyl-4-oxo-2,3-dihydroquinolin-3-yl)-6-(2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one;8-(2-methyl-1-oxo-3,4-dihydroisoquinolin-3-yl)-2-[4-piperazin-1-yl-3-(trifluoromethyl)anilino]-6-(pyridin-3-ylamino)pyrido[2,3-d]pyrimidin-7-one;8-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-6-(5-methyl-1,3-thiazol-4-yl)-2-(4-pyrrolidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(1-methylpiperidin-2-yl)-8-(4-oxo-2,3-dihydrothiochromen-3-yl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]pyrido[2,3-d]pyrimidin-7-one
CID 157741507
N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-2-[3-(1,1-difluoroethyl)phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(4,6-dimethyl-2-pyridinyl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(4,5-dimethyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methylpyrimidin-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-2-ylquinoline-8-carboxamide
CID 158377843
1-[6-[Difluoro(pyrimidin-5-yl)methyl]quinolin-8-yl]-2-(5-methyl-2-pyridinyl)ethanone;1-[6-[difluoro(pyrimidin-5-yl)methyl]quinolin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-[fluoro(pyrimidin-5-yl)methyl]quinolin-8-yl]-2-(5-methyl-2-pyridinyl)ethanone;2-(5-methyl-2-pyridinyl)-1-[6-(pyrimidine-5-carbonyl)quinolin-8-yl]ethanone;2-(4-methyl-1,3-thiazol-2-yl)-1-[6-(pyrimidine-5-carbonyl)quinolin-8-yl]ethanone
CID 158804714
2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide
CID 159480476
3-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoxaline-5-carboxamide;3-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoxaline-5-carboxamide;3-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoxaline-5-carboxamide;N-[2-[3-[(dimethylamino)methyl]phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;bis(N-[2-[3-(piperidin-1-ylmethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide)
CID 161355856
2-[3-(1,1-difluoroethyl)phenyl]-N-pyridazin-3-ylquinoline-8-carboxamide;2-(3-piperidin-1-ylphenyl)-N-pyridin-2-ylquinoline-8-carboxamide;2-(3-piperidin-1-ylphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-piperidin-1-ylphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-piperidin-1-ylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-[2-[3-(pyrrolidin-1-ylmethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide
CID 161416839
2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(morpholin-4-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-(3-piperidin-1-ylphenyl)quinoline-8-carboxamide;N-(4-methyl-1,3-thiazol-2-yl)-2-(3-piperidin-1-ylphenyl)quinoline-8-carboxamide;N-(5-methyl-1,3-thiazol-2-yl)-2-(3-piperidin-1-ylphenyl)quinoline-8-carboxamide;N-(5-methyl-1,3-thiazol-2-yl)-2-pyridin-3-ylquinoline-8-carboxamide;2-phenyl-N-[6-(piperidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide
CID 161732947

Frequently Asked Questions

What is the IUPAC name of 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide?
The IUPAC name of 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide (CID 160530619) is 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide.
What is the SMILES notation for 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide?
The canonical SMILES for 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide is CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccnc4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccncc4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ccncn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4nncs4)c3n2)c1.Cc1csc(NC(=O)c2cccc3ccc(-c4cccc(C(C)(F)F)c4)nc23)n1.
What is the InChIKey of 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide?
The InChIKey is QVMGRNHFKSBWGU-UHFFFAOYSA-N. The full InChI is InChI=1S/3C23H17F2N3O.C22H16F2N4O.C22H17F2N3OS.C20H14F2N4OS/c1-23(24,25)17-7-2-6-16(13-17)20-11-10-15-5-3-9-19(21(15)28-20)22(29)27-18-8-4-12-26-14-18;1-23(24,25)17-6-2-5-16(14-17)20-9-8-15-4-3-7-19(21(15)28-20)22(29)27-18-10-12-26-13-11-18;1-23(24,25)17-8-4-7-16(14-17)19-12-11-15-6-5-9-18(21(15)27-19)22(29)28-20-10-2-3-13-26-20;1-22(23,24)16-6-2-5-15(12-16)18-9-8-14-4-3-7-17(20(14)27-18)21(29)28-19-10-11-25-13-26-19;1-13-12-29-21(25-13)27-20(28)17-8-4-5-14-9-10-18(26-19(14)17)15-6-3-7-16(11-15)22(2,23)24;1-20(21,22)14-6-2-5-13(10-14)16-9-8-12-4-3-7-15(17(12)24-16)18(27)25-19-26-23-11-28-19/h2-14H,1H3,(H,27,29);2-14H,1H3,(H,26,27,29);2-14H,1H3,(H,26,28,29);2-13H,1H3,(H,25,26,28,29);3-12H,1-2H3,(H,25,27,28);2-11H,1H3,(H,25,26,27).
What are the key properties of 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide?
2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide has a molecular weight of 2364.49 g/mol, XLogP of 33.19, 24 rotatable bonds, 6 hydrogen bond donors, and 22 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(1,1-difluoroethyl)phenyl]-N-(4-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-2-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-3-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyridin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-(1,3,4-thiadiazol-2-yl)quinoline-8-carboxamide is sourced from PubChem (CID 160530619), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).