1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine

C93H100F12N34O8S2 — CID 160534184

About 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine

1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine (PubChem CID 160534184) has the molecular formula C93H100F12N34O8S2 and a molecular weight of 2114.16 g/mol. Its IUPAC name is 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine.

Molecular Properties

• Compound Name: 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine
• PubChem CID: 160534184
• Molecular Formula: C93H100F12N34O8S2
• Molecular Weight: 2114.16 g/mol
• Exact Mass: 2112.77
• IUPAC Name: 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine
• SMILES: CC1CN(c2nccc(-c3cnc4cnc(C(F)F)cn34)n2)CC(C(=O)NS(C)(=O)=O)C1(F)F.CNC(=O)C1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.CS(=O)(=O)CCCC1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.NC(=O)C1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.NC(=O)CCC1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1
• InChI: InChI=1S/C20H24F2N6O2S.C19H19F4N7O3S.C19H21F2N7O.C18H19F2N7O.C17H17F2N7O/c1-31(29,30)9-3-5-14-4-2-8-27(12-14)17-6-7-23-20(26-17)16-10-25-18-11-24-15(19(21)22)13-28(16)18;1-10-7-29(8-11(19(10,22)23)17(31)28-34(2,32)33)18-24-4-3-12(27-18)14-5-26-15-6-25-13(16(20)21)9-30(14)15;20-18(21)13-11-28-14(8-25-17(28)9-24-13)19-23-6-5-16(26-19)27-7-1-2-12(10-27)3-4-15(22)29;1-21-18(28)11-3-2-6-26(9-11)14-4-5-22-17(25-14)13-7-24-15-8-23-12(16(19)20)10-27(13)15;18-15(19)11-9-26-12(6-23-14(26)7-22-11)17-21-4-3-13(24-17)25-5-1-2-10(8-25)16(20)27/h6-7,10-11,13-14,19H,2-5,8-9,12H2,1H3;3-6,9-11,16H,7-8H2,1-2H3,(H,28,31);5-6,8-9,11-12,18H,1-4,7,10H2,(H2,22,29);4-5,7-8,10-11,16H,2-3,6,9H2,1H3,(H,21,28);3-4,6-7,9-10,15H,1-2,5,8H2,(H2,20,27)
• InChIKey: QVXZEXBHAUJUEV-UHFFFAOYSA-N
• XLogP: 11.59
• TPSA: 508.71 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 38
• Rotatable Bonds: 26
• Heavy Atoms: 149
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2114.16
LogP ≤ 5	11.59
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	38

Frequently Asked Questions

What is the IUPAC name of 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine?

The IUPAC name of 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine (CID 160534184) is 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine.

What is the SMILES notation for 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine?

The canonical SMILES for 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine is CC1CN(c2nccc(-c3cnc4cnc(C(F)F)cn34)n2)CC(C(=O)NS(C)(=O)=O)C1(F)F.CNC(=O)C1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.CS(=O)(=O)CCCC1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.NC(=O)C1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.NC(=O)CCC1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.

What is the InChIKey of 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine?

The InChIKey is QVXZEXBHAUJUEV-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H24F2N6O2S.C19H19F4N7O3S.C19H21F2N7O.C18H19F2N7O.C17H17F2N7O/c1-31(29,30)9-3-5-14-4-2-8-27(12-14)17-6-7-23-20(26-17)16-10-25-18-11-24-15(19(21)22)13-28(16)18;1-10-7-29(8-11(19(10,22)23)17(31)28-34(2,32)33)18-24-4-3-12(27-18)14-5-26-15-6-25-13(16(20)21)9-30(14)15;20-18(21)13-11-28-14(8-25-17(28)9-24-13)19-23-6-5-16(26-19)27-7-1-2-12(10-27)3-4-15(22)29;1-21-18(28)11-3-2-6-26(9-11)14-4-5-22-17(25-14)13-7-24-15-8-23-12(16(19)20)10-27(13)15;18-15(19)11-9-26-12(6-23-14(26)7-22-11)17-21-4-3-13(24-17)25-5-1-2-10(8-25)16(20)27/h6-7,10-11,13-14,19H,2-5,8-9,12H2,1H3;3-6,9-11,16H,7-8H2,1-2H3,(H,28,31);5-6,8-9,11-12,18H,1-4,7,10H2,(H2,22,29);4-5,7-8,10-11,16H,2-3,6,9H2,1H3,(H,21,28);3-4,6-7,9-10,15H,1-2,5,8H2,(H2,20,27).

What are the key properties of 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine?

1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine has a molecular weight of 2114.16 g/mol, XLogP of 11.59, 26 rotatable bonds, 4 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine is sourced from PubChem (CID 160534184), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).