N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine

C118H136F15N35O10S4 — CID 158975962

IUPACN-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
SMILESCC1(C)CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CCN1C(=O)C1CCC(=O)CC1.CS(=O)(=O)C1CC(N2CCN(c3ccnc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@@H]2c2cn[nH]c2)C1.C[C@@H]1[C@H](CNS(C)(=O)=O)N(C2CC2)[C@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.C[C@H]1[C@@H](CNS(C)(=O)=O)N(C2CC2)[C@@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.C[C@H]1[C@H](CNS(C)(=O)=O)N(C2CC2)[C@@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1
InChIInChI=1S/C25H27F3N6O2.C24H25F3N8O2S.3C23H28F3N7O2S/c1-24(2)15-32(11-12-34(24)23(36)16-3-6-18(35)7-4-16)21-9-10-29-22(31-21)19-13-30-20-8-5-17(14-33(19)20)25(26,27)28;1-38(36,37)18-8-17(9-18)34-7-6-33(14-20(34)15-10-30-31-11-15)22-4-5-28-23(32-22)19-12-29-21-3-2-16(13-35(19)21)24(25,26)27;3*1-14-12-31(15(2)18(11-29-36(3,34)35)33(14)17-5-6-17)21-8-9-27-22(30-21)19-10-28-20-7-4-16(13-32(19)20)23(24,25)26/h5,8-10,13-14,16H,3-4,6-7,11-12,15H2,1-2H3;2-5,10-13,17-18,20H,6-9,14H2,1H3,(H,30,31);3*4,7-10,13-15,17-18,29H,5-6,11-12H2,1-3H3/t;17?,18?,20-;2*14-,15-,18+;14-,15-,18-/m.1100/s1
InChIKeyJOJYOHVVYQPXDW-CFKIQJHGSA-N
MW2617.86 g/mol
LogP15.34
Rot. Bonds26

About N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine

N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine (PubChem CID 158975962) has the molecular formula C118H136F15N35O10S4 and a molecular weight of 2617.86 g/mol. Its IUPAC name is N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine.

Molecular Properties

Compound NameN-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
PubChem CID158975962
Molecular FormulaC118H136F15N35O10S4
Molecular Weight2617.86 g/mol
Exact Mass2615.99
IUPAC NameN-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
SMILESCC1(C)CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CCN1C(=O)C1CCC(=O)CC1.CS(=O)(=O)C1CC(N2CCN(c3ccnc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@@H]2c2cn[nH]c2)C1.C[C@@H]1[C@H](CNS(C)(=O)=O)N(C2CC2)[C@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.C[C@H]1[C@@H](CNS(C)(=O)=O)N(C2CC2)[C@@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.C[C@H]1[C@H](CNS(C)(=O)=O)N(C2CC2)[C@@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1
InChIInChI=1S/C25H27F3N6O2.C24H25F3N8O2S.3C23H28F3N7O2S/c1-24(2)15-32(11-12-34(24)23(36)16-3-6-18(35)7-4-16)21-9-10-29-22(31-21)19-13-30-20-8-5-17(14-33(19)20)25(26,27)28;1-38(36,37)18-8-17(9-18)34-7-6-33(14-20(34)15-10-30-31-11-15)22-4-5-28-23(32-22)19-12-29-21-3-2-16(13-35(19)21)24(25,26)27;3*1-14-12-31(15(2)18(11-29-36(3,34)35)33(14)17-5-6-17)21-8-9-27-22(30-21)19-10-28-20-7-4-16(13-32(19)20)23(24,25)26/h5,8-10,13-14,16H,3-4,6-7,11-12,15H2,1-2H3;2-5,10-13,17-18,20H,6-9,14H2,1H3,(H,30,31);3*4,7-10,13-15,17-18,29H,5-6,11-12H2,1-3H3/t;17?,18?,20-;2*14-,15-,18+;14-,15-,18-/m.1100/s1
InChIKeyJOJYOHVVYQPXDW-CFKIQJHGSA-N
XLogP15.34
TPSA483.27 Ų
H-Bond Donors4
H-Bond Acceptors40
Rotatable Bonds26
Heavy Atoms182
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002617.86
LogP ≤ 515.34
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1040

Analyze N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[(1R)-1-[(2S,3S)-1-cyclopropyl-3-methyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]ethyl]methanesulfonamide;N-[(1S)-1-[(2R,3R)-1-cyclopropyl-3-methyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]ethyl]methanesulfonamide;3-[2-[(3R)-4-cyclopropyl-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;(3-hydroxy-3-methylcyclobutyl)-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;3-[4-[4-[(1-methylcyclopropyl)methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
CID 157355046
N-[(1R)-1-[(2S,3S)-1-cyclopropyl-3-methyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]ethyl]methanesulfonamide;N-[(1S)-1-[(3R)-1-cyclopropyl-3-methyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]ethyl]methanesulfonamide;3-[2-[(3R)-4-cyclopropyl-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;(3-hydroxy-3-methylcyclobutyl)-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;3-[4-[4-[(1-methylcyclopropyl)methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
CID 157355047
cyclopropyl-[(2R,6S)-2,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;(3,3-difluorocyclobutyl)-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;N-[(1S)-1-[(2R)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]morpholin-2-yl]ethyl]methanesulfonamide;N-[(1R)-1-[(2S)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]morpholin-2-yl]ethyl]methanesulfonamide;N-[(1R)-1-[(2R)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]morpholin-2-yl]ethyl]methanesulfonamide
CID 157421507
3-[6-(3a,7a-dihydro-1H-indol-6-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine;N-[[1-[6-[5-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]pyrimidin-4-yl]-4,4-difluoro-2,5-dimethylpiperidin-3-yl]methyl]methanesulfonamide;[1-[6-[5-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]pyrimidin-4-yl]-5-methylpiperidin-3-yl]imino-dimethyl-oxo-lambda6-sulfane;3-(2-phenyl-4-pyridinyl)pyrazolo[1,5-a]pyrimidine;2-(4-pyrazolo[1,5-a]pyrimidin-3-yl-2-pyridinyl)-3,4,7,8,9,9a-hexahydro-1H-pyrido[1,2-a]pyrazin-6-one
CID 157452934
N-[(1R)-1-[(2R,3R)-1-cyclopropyl-3-methyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]ethyl]methanesulfonamide;3-[4-[(3S)-4-cyclopropyl-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;1-[(2R,6S)-2,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]-2-(oxetan-3-yl)ethanone;3-[4-[(3R)-4-(2-oxaspiro[3.3]heptan-6-yl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-(2-oxaspiro[3.3]heptan-6-yl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
CID 157922696
imino-methyl-oxo-[[(3S)-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]methyl]-lambda6-sulfane;2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]morpholine;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-1,2,5,6,8,8a-hexahydroimidazo[1,5-a]pyrazin-3-one;N-[[(2S)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]morpholin-2-yl]methyl]methanesulfonamide
CID 158622568
N-[[1-cyclopropyl-4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methylpiperazin-2-yl]methyl]methanesulfonamide;3-[4-[4-[(2-methylcyclopropyl)methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[(2S,3S)-3-methyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;3-[4-[3-(1H-pyrazol-4-yl)-4-(spiro[2.2]pentan-2-ylmethyl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;(3R)-3-[(2S)-2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one
CID 158969208
[1-(difluoromethyl)cyclopropyl]-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;[(2S,6R)-2,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]-(1-methylcyclopropyl)methanone;[(1S,2S)-2-fluorocyclopropyl]-[2-(2H-pyrrol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone;3-[4-[(3R)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;oxan-4-yl-[2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]methanone
CID 159946676
1-[4-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]-4,4-difluoro-5-methyl-N-methylsulfonylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-N-methylpiperidine-3-carboxamide;1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;3-[1-[2-[6-(difluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propanamide;6-(difluoromethyl)-3-[4-[3-(3-methylsulfonylpropyl)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine
CID 160534184
CID 161135533
CID 161135533
3-[4-[(3R)-3-(1H-pyrazol-4-yl)-4-[[(2R)-spiro[2.2]pentan-2-yl]methyl]piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-3-(1H-pyrazol-4-yl)-4-[[(2R)-spiro[2.2]pentan-2-yl]methyl]piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-3-(1H-pyrazol-4-yl)-4-[[(2S)-spiro[2.2]pentan-2-yl]methyl]piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-3-(1H-pyrazol-4-yl)-4-[[(2S)-spiro[2.2]pentan-2-yl]methyl]piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;6-[(2S)-2-(1H-pyrazol-4-yl)-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-1-yl]-2lambda6-thiaspiro[3.3]heptane 2,2-dioxide
CID 161176481
2-tert-butyl-2-azabicyclo[3.1.0]hexane;1-[(1R,5S)-3-tert-butyl-3-azabicyclo[3.1.0]hexan-6-yl]ethanone;1-(3-tert-butyl-3-azabicyclo[3.1.0]hexan-6-yl)ethanone;1-tert-butyl-3-(1,1-difluoroethyl)pyrrolidine;1-tert-butyl-3,3-difluoro-4-methylpyrrolidine;1-tert-butyl-3,3-difluoropyrrolidine;(3S,4R)-1-tert-butyl-3,4-difluoropyrrolidine;6-tert-butyl-5,7-dihydropyrrolo[3,4-b]pyridine;(3R)-1-tert-butyl-3-ethyl-3-methylpyrrolidine;1-tert-butyl-3-fluoro-3-methylpyrrolidine;(3R)-1-tert-butyl-3-methylpyrrolidine;(3S)-1-tert-butyl-3-methylpyrrolidine;1-tert-butyl-3-methylsulfonylpyrrolidine;1-tert-butylpyrrolidine-3-carboxamide;2-(1-tert-butylpyrrolidin-3-yl)-1-methylimidazole;5-(1-tert-butylpyrrolidin-3-yl)-1-methylimidazole;4-(1-tert-butylpyrrolidin-3-yl)-2-methylpyrimidine;2-(1-tert-butylpyrrolidin-3-yl)-1H-pyrrole
CID 161475652

Frequently Asked Questions

What is the IUPAC name of N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?
The IUPAC name of N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CID 158975962) is N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine.
What is the SMILES notation for N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?
The canonical SMILES for N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine is CC1(C)CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CCN1C(=O)C1CCC(=O)CC1.CS(=O)(=O)C1CC(N2CCN(c3ccnc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@@H]2c2cn[nH]c2)C1.C[C@@H]1[C@H](CNS(C)(=O)=O)N(C2CC2)[C@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.C[C@H]1[C@@H](CNS(C)(=O)=O)N(C2CC2)[C@@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.C[C@H]1[C@H](CNS(C)(=O)=O)N(C2CC2)[C@@H](C)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.
What is the InChIKey of N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?
The InChIKey is JOJYOHVVYQPXDW-CFKIQJHGSA-N. The full InChI is InChI=1S/C25H27F3N6O2.C24H25F3N8O2S.3C23H28F3N7O2S/c1-24(2)15-32(11-12-34(24)23(36)16-3-6-18(35)7-4-16)21-9-10-29-22(31-21)19-13-30-20-8-5-17(14-33(19)20)25(26,27)28;1-38(36,37)18-8-17(9-18)34-7-6-33(14-20(34)15-10-30-31-11-15)22-4-5-28-23(32-22)19-12-29-21-3-2-16(13-35(19)21)24(25,26)27;3*1-14-12-31(15(2)18(11-29-36(3,34)35)33(14)17-5-6-17)21-8-9-27-22(30-21)19-10-28-20-7-4-16(13-32(19)20)23(24,25)26/h5,8-10,13-14,16H,3-4,6-7,11-12,15H2,1-2H3;2-5,10-13,17-18,20H,6-9,14H2,1H3,(H,30,31);3*4,7-10,13-15,17-18,29H,5-6,11-12H2,1-3H3/t;17?,18?,20-;2*14-,15-,18+;14-,15-,18-/m.1100/s1.
What are the key properties of N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?
N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine has a molecular weight of 2617.86 g/mol, XLogP of 15.34, 26 rotatable bonds, 4 hydrogen bond donors, and 40 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[(2R,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3S,6S)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;N-[[(2S,3R,6R)-1-cyclopropyl-3,6-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazin-2-yl]methyl]methanesulfonamide;4-[2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperazine-1-carbonyl]cyclohexan-1-one;3-[4-[(3S)-4-(3-methylsulfonylcyclobutyl)-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine is sourced from PubChem (CID 158975962), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).