7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one

C105H69N19O7S3 — CID 160551284

IUPAC7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one
SMILESCc1ccc(-c2nc3[nH]c(=O)c(-c4cncnc4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-n4ccccc4=O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(-n4ccccc4=O)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4cncnc4)cc3cc2-c2ccc3ncccc3c2)s1
InChIInChI=1S/C27H18N4O3.C27H18N4O2S.C26H17N5OS.C25H16N6OS/c2*1-16-7-10-23(34-16)25-20(17-8-9-21-18(13-17)5-4-11-28-21)14-19-15-22(27(33)30-26(19)29-25)31-12-3-2-6-24(31)32;1-15-4-7-23(33-15)24-20(16-5-6-22-17(9-16)3-2-8-29-22)10-18-11-21(19-12-27-14-28-13-19)26(32)31-25(18)30-24;1-14-29-12-22(33-14)23-19(15-4-5-21-16(7-15)3-2-6-28-21)8-17-9-20(18-10-26-13-27-11-18)25(32)31-24(17)30-23/h2*2-15H,1H3,(H,29,30,33);2-14H,1H3,(H,30,31,32);2-13H,1H3,(H,30,31,32)
InChIKeyQYCJDXASAJPXKX-UHFFFAOYSA-N
MW1805.03 g/mol
LogP20.84
Rot. Bonds12

About 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one

7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one (PubChem CID 160551284) has the molecular formula C105H69N19O7S3 and a molecular weight of 1805.03 g/mol. Its IUPAC name is 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one.

Molecular Properties

Compound Name7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one
PubChem CID160551284
Molecular FormulaC105H69N19O7S3
Molecular Weight1805.03 g/mol
Exact Mass1803.48
IUPAC Name7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one
SMILESCc1ccc(-c2nc3[nH]c(=O)c(-c4cncnc4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-n4ccccc4=O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(-n4ccccc4=O)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4cncnc4)cc3cc2-c2ccc3ncccc3c2)s1
InChIInChI=1S/C27H18N4O3.C27H18N4O2S.C26H17N5OS.C25H16N6OS/c2*1-16-7-10-23(34-16)25-20(17-8-9-21-18(13-17)5-4-11-28-21)14-19-15-22(27(33)30-26(19)29-25)31-12-3-2-6-24(31)32;1-15-4-7-23(33-15)24-20(16-5-6-22-17(9-16)3-2-8-29-22)10-18-11-21(19-12-27-14-28-13-19)26(32)31-25(18)30-24;1-14-29-12-22(33-14)23-19(15-4-5-21-16(7-15)3-2-6-28-21)8-17-9-20(18-10-26-13-27-11-18)25(32)31-24(17)30-23/h2*2-15H,1H3,(H,29,30,33);2-14H,1H3,(H,30,31,32);2-13H,1H3,(H,30,31,32)
InChIKeyQYCJDXASAJPXKX-UHFFFAOYSA-N
XLogP20.84
TPSA356.15 Ų
H-Bond Donors4
H-Bond Acceptors25
Rotatable Bonds12
Heavy Atoms134
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001805.03
LogP ≤ 520.84
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1025

Analyze 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-5-[2-[1-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-7-[(3,4-difluorophenyl)methyl]-8-oxo-5,6-dihydro-2,7-naphthyridin-3-yl]ethoxy]-N-[(3,4-difluorophenyl)methyl]pyridine-3-carboxamide
CID 135243166
2-Amino-5-[2-fluoro-5-(furan-3-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-thiophen-3-ylphenyl)-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 158760585
N-[6-[3-(1,1-difluoroethoxy)phenyl]pyrido[3,2-d]pyrimidin-4-yl]-1,3-thiazole-4-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]quinoline-8-carboxamide;2-[3-(1-fluoroethyl)phenyl]-N-[4-(morpholin-4-ylmethyl)phenyl]quinoline-8-carboxamide;7-[3-(1-fluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-2-pyridinyl]naphthalene-1-carboxamide;2-[2-(1-fluoroethyl)-4-pyridinyl]-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
CID 159499663
2-Amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 160685595
2-Amino-5-[3-(furan-3-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(2-methylpyrimidin-5-yl)phenyl]-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(1,3-oxazol-4-yl)phenyl]-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(1,3-oxazol-5-yl)phenyl]-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(1,3-thiazol-5-yl)phenyl]-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-thiophen-3-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 161609887
2-[3-[4-(pyridin-4-ylmethoxy)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-1,3-oxazole;N-(pyridin-4-ylmethyl)-2-[8-(1,3-thiazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]pyrido[3,4-d]pyrimidin-4-amine
CID 67992269
ethyl 4-[2-[[4,4-dimethyl-8-(2-methylpropyl)-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12,14,16-hexaen-13-yl]amino]ethyl]piperazine-1-carboxylate;8-(furan-2-yl)-4,4-dimethyl-N-(2-morpholin-4-ylethyl)-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12,14,16-hexaen-13-amine
CID 87799805
N-[[4-[2-(2-amino-3-pyridinyl)-5-(furan-2-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide;2-[4-[2-(2-amino-3-pyridinyl)-6-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]-N-(2-methylquinolin-6-yl)acetamide;N-[[4-[2-(2-amino-3-pyridinyl)-5-thiophen-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
CID 89120208
7-(5-methylfuran-2-yl)-6-quinolin-6-yl-3-(1,3-thiazol-2-yl)-1H-1,8-naphthyridin-2-one
CID 137438088
2-[5-(1,3-benzothiazol-2-yl)-7-(1H-indol-2-yl)-2-isoquinolin-1-yl-3-quinazolin-2-yl-8-quinolin-2-ylquinoxalin-6-yl]-1,3-benzoxazole
CID 140983497
ethane;8-(4-methyl-2,3-dihydro-1,4-benzoxazin-7-yl)-N-(1,3-thiazol-2-yl)quinoline-2-carboxamide;8-(3-pyrrolidin-1-ylphenyl)-N-(1,3-thiazol-2-yl)quinoline-2-carboxamide
CID 144049446
3-(5-methylfuran-2-yl)-2-quinolin-6-yl-7-(1,3-thiazol-2-yl)-5H-pyrido[2,3-b]pyrazin-6-one
CID 154657635

Frequently Asked Questions

What is the IUPAC name of 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?
The IUPAC name of 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one (CID 160551284) is 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one.
What is the SMILES notation for 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?
The canonical SMILES for 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one is Cc1ccc(-c2nc3[nH]c(=O)c(-c4cncnc4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-n4ccccc4=O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(-n4ccccc4=O)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4cncnc4)cc3cc2-c2ccc3ncccc3c2)s1.
What is the InChIKey of 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?
The InChIKey is QYCJDXASAJPXKX-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H18N4O3.C27H18N4O2S.C26H17N5OS.C25H16N6OS/c2*1-16-7-10-23(34-16)25-20(17-8-9-21-18(13-17)5-4-11-28-21)14-19-15-22(27(33)30-26(19)29-25)31-12-3-2-6-24(31)32;1-15-4-7-23(33-15)24-20(16-5-6-22-17(9-16)3-2-8-29-22)10-18-11-21(19-12-27-14-28-13-19)26(32)31-25(18)30-24;1-14-29-12-22(33-14)23-19(15-4-5-21-16(7-15)3-2-6-28-21)8-17-9-20(18-10-26-13-27-11-18)25(32)31-24(17)30-23/h2*2-15H,1H3,(H,29,30,33);2-14H,1H3,(H,30,31,32);2-13H,1H3,(H,30,31,32).
What are the key properties of 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?
7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one has a molecular weight of 1805.03 g/mol, XLogP of 20.84, 12 rotatable bonds, 4 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 7-(5-methylfuran-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-(2-oxo-1-pyridinyl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyrimidin-5-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one is sourced from PubChem (CID 160551284), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).