N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride

C117H153Cl4F9N28O11 — CID 160553310

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride (PubChem CID 160553310) has the molecular formula C117H153Cl4F9N28O11 and a molecular weight of 2440.49 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride
• PubChem CID: 160553310
• Molecular Formula: C117H153Cl4F9N28O11
• Molecular Weight: 2440.49 g/mol
• Exact Mass: 2437.09
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride
• SMILES: CC(C)(C)OCCC(=O)Nc1nc2cccnc2n1CC(F)(F)F.COCCn1c(NC(=O)CCC2CCCC2)nc2ccc(Cl)nc21.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2n1.Cc1ccc2nc(NC(=O)CCOC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCOC(C)(C)C)n(CC(F)(F)F)c2n1.Cc1cccc(CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)c1.Cl.Cl
• InChI: InChI=1S/C19H19ClN4O.C18H26N4O2.C17H23ClN4O2.C17H24N4O.C16H21F3N4O2.C15H19F3N4O2.C15H19F3N4O.2ClH/c1-12-4-2-5-13(10-12)11-17(25)23-19-21-15-8-9-16(20)22-18(15)24(19)14-6-3-7-14;1-12-8-9-14-16(19-12)22(13-6-5-7-13)17(20-14)21-15(23)10-11-24-18(2,3)4;1-24-11-10-22-16-13(7-8-14(18)20-16)19-17(22)21-15(23)9-6-12-4-2-3-5-12;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-10-5-6-11-13(20-10)23(9-16(17,18)19)14(21-11)22-12(24)7-8-25-15(2,3)4;1-14(2,3)24-8-6-11(23)21-13-20-10-5-4-7-19-12(10)22(13)9-15(16,17)18;1-9-5-6-10-12(19-9)22(8-15(16,17)18)13(20-10)21-11(23)7-14(2,3)4;;/h2,4-5,8-10,14H,3,6-7,11H2,1H3,(H,21,23,25);8-9,13H,5-7,10-11H2,1-4H3,(H,20,21,23);7-8,12H,2-6,9-11H2,1H3,(H,19,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);5-6H,7-9H2,1-4H3,(H,21,22,24);4-5,7H,6,8-9H2,1-3H3,(H,20,21,23);5-6H,7-8H2,1-4H3,(H,20,21,23);2*1H
• InChIKey: JKLOLSXKZGFTIR-UHFFFAOYSA-N
• XLogP: 26.49
• TPSA: 455.59 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 32
• Rotatable Bonds: 32
• Heavy Atoms: 169
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2440.49
LogP ≤ 5	26.49
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	32

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride (CID 160553310) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride is CC(C)(C)OCCC(=O)Nc1nc2cccnc2n1CC(F)(F)F.COCCn1c(NC(=O)CCC2CCCC2)nc2ccc(Cl)nc21.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2n1.Cc1ccc2nc(NC(=O)CCOC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCOC(C)(C)C)n(CC(F)(F)F)c2n1.Cc1cccc(CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)c1.Cl.Cl.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride?

The InChIKey is JKLOLSXKZGFTIR-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H19ClN4O.C18H26N4O2.C17H23ClN4O2.C17H24N4O.C16H21F3N4O2.C15H19F3N4O2.C15H19F3N4O.2ClH/c1-12-4-2-5-13(10-12)11-17(25)23-19-21-15-8-9-16(20)22-18(15)24(19)14-6-3-7-14;1-12-8-9-14-16(19-12)22(13-6-5-7-13)17(20-14)21-15(23)10-11-24-18(2,3)4;1-24-11-10-22-16-13(7-8-14(18)20-16)19-17(22)21-15(23)9-6-12-4-2-3-5-12;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-10-5-6-11-13(20-10)23(9-16(17,18)19)14(21-11)22-12(24)7-8-25-15(2,3)4;1-14(2,3)24-8-6-11(23)21-13-20-10-5-4-7-19-12(10)22(13)9-15(16,17)18;1-9-5-6-10-12(19-9)22(8-15(16,17)18)13(20-10)21-11(23)7-14(2,3)4;;/h2,4-5,8-10,14H,3,6-7,11H2,1H3,(H,21,23,25);8-9,13H,5-7,10-11H2,1-4H3,(H,20,21,23);7-8,12H,2-6,9-11H2,1H3,(H,19,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);5-6H,7-9H2,1-4H3,(H,21,22,24);4-5,7H,6,8-9H2,1-3H3,(H,20,21,23);5-6H,7-8H2,1-4H3,(H,20,21,23);2*1H.

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride has a molecular weight of 2440.49 g/mol, XLogP of 26.49, 32 rotatable bonds, 7 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(3-methylphenyl)acetamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3-cyclopentylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-[(2-methylpropan-2-yl)oxy]-N-[5-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;3-[(2-methylpropan-2-yl)oxy]-N-[3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;dihydrochloride is sourced from PubChem (CID 160553310), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).