6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine

C98H63F21N26O5 — CID 160638659

About 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine

6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine (PubChem CID 160638659) has the molecular formula C98H63F21N26O5 and a molecular weight of 2083.72 g/mol. Its IUPAC name is 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine.

Molecular Properties

• Compound Name: 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
• PubChem CID: 160638659
• Molecular Formula: C98H63F21N26O5
• Molecular Weight: 2083.72 g/mol
• Exact Mass: 2082.51
• IUPAC Name: 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
• SMILES: FC(F)(F)c1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4cnccn34)n2)cc1.FC(F)(F)c1ccc(Nc2cncc(-c3cccc4nc(C5CC5)cn34)n2)cc1.FC(F)Oc1ccc(Nc2cncc(-c3cccc4nc(C5CC5)cn34)n2)cc1.FC1(F)Oc2ccc(Nc3cncc(-c4c(C(F)(F)F)nc5ccccn45)n3)cc2O1.FC1(F)Oc2ccc(Nc3cncc(-c4c(C(F)(F)F)nn5ccccc45)n3)cc2O1
• InChI: InChI=1S/C21H16F3N5.C21H17F2N5O.2C19H10F5N5O2.C18H10F6N6/c22-21(23,24)14-6-8-15(9-7-14)26-19-11-25-10-16(27-19)18-2-1-3-20-28-17(12-29(18)20)13-4-5-13;22-21(23)29-15-8-6-14(7-9-15)25-19-11-24-10-16(26-19)18-2-1-3-20-27-17(12-28(18)20)13-4-5-13;20-18(21,22)17-16(29-6-2-1-3-15(29)28-17)11-8-25-9-14(27-11)26-10-4-5-12-13(7-10)31-19(23,24)30-12;20-18(21,22)17-16(12-3-1-2-6-29(12)28-17)11-8-25-9-15(27-11)26-10-4-5-13-14(7-10)31-19(23,24)30-13;19-17(20,21)10-1-3-11(4-2-10)27-13-8-26-7-12(28-13)15-16(18(22,23)24)29-14-9-25-5-6-30(14)15/h1-3,6-13H,4-5H2,(H,26,27);1-3,6-13,21H,4-5H2,(H,25,26);2*1-9H,(H,26,27);1-9H,(H,27,28)
• InChIKey: RIWKYWPCRXOBLO-UHFFFAOYSA-N
• XLogP: 25.16
• TPSA: 334.59 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 31
• Rotatable Bonds: 19
• Heavy Atoms: 150
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2083.72
LogP ≤ 5	25.16
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

The IUPAC name of 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine (CID 160638659) is 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine.

What is the SMILES notation for 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

The canonical SMILES for 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine is FC(F)(F)c1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4cnccn34)n2)cc1.FC(F)(F)c1ccc(Nc2cncc(-c3cccc4nc(C5CC5)cn34)n2)cc1.FC(F)Oc1ccc(Nc2cncc(-c3cccc4nc(C5CC5)cn34)n2)cc1.FC1(F)Oc2ccc(Nc3cncc(-c4c(C(F)(F)F)nc5ccccn45)n3)cc2O1.FC1(F)Oc2ccc(Nc3cncc(-c4c(C(F)(F)F)nn5ccccc45)n3)cc2O1.

What is the InChIKey of 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

The InChIKey is RIWKYWPCRXOBLO-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H16F3N5.C21H17F2N5O.2C19H10F5N5O2.C18H10F6N6/c22-21(23,24)14-6-8-15(9-7-14)26-19-11-25-10-16(27-19)18-2-1-3-20-28-17(12-29(18)20)13-4-5-13;22-21(23)29-15-8-6-14(7-9-15)25-19-11-24-10-16(26-19)18-2-1-3-20-27-17(12-28(18)20)13-4-5-13;20-18(21,22)17-16(29-6-2-1-3-15(29)28-17)11-8-25-9-14(27-11)26-10-4-5-12-13(7-10)31-19(23,24)30-12;20-18(21,22)17-16(12-3-1-2-6-29(12)28-17)11-8-25-9-15(27-11)26-10-4-5-13-14(7-10)31-19(23,24)30-13;19-17(20,21)10-1-3-11(4-2-10)27-13-8-26-7-12(28-13)15-16(18(22,23)24)29-14-9-25-5-6-30(14)15/h1-3,6-13H,4-5H2,(H,26,27);1-3,6-13,21H,4-5H2,(H,25,26);2*1-9H,(H,26,27);1-9H,(H,27,28).

What are the key properties of 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine has a molecular weight of 2083.72 g/mol, XLogP of 25.16, 19 rotatable bonds, 5 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(2-cyclopropylimidazo[1,2-a]pyridin-5-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;N-(2,2-difluoro-1,3-benzodioxol-5-yl)-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine is sourced from PubChem (CID 160638659), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).