5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine

C62H60Cl2F5N23O — CID 160667879

IUPAC5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine
SMILESCC(C)n1c(N)nc2ccc(C(F)(F)F)nc21.Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cc1.Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cn1.Nc1nc2ccc(N3CCOCC3)nc2n1C1CCC1
InChIInChI=1S/C15H15N5.C14H19N5O.C12H8ClFN4.C11H7ClFN5.C10H11F3N4/c16-15-19-13-7-6-12(10-3-2-8-17-9-10)18-14(13)20(15)11-4-1-5-11;15-14-16-11-4-5-12(18-6-8-20-9-7-18)17-13(11)19(14)10-2-1-3-10;13-10-6-5-9-11(17-10)18(12(15)16-9)8-3-1-7(14)2-4-8;12-8-3-2-7-10(17-8)18(11(14)16-7)9-4-1-6(13)5-15-9;1-5(2)17-8-6(15-9(17)14)3-4-7(16-8)10(11,12)13/h2-3,6-9,11H,1,4-5H2,(H2,16,19);4-5,10H,1-3,6-9H2,(H2,15,16);1-6H,(H2,15,16);1-5H,(H2,14,16);3-5H,1-2H3,(H2,14,15)
InChIKeyRMNVYOSISNQXSI-UHFFFAOYSA-N
MW1309.22 g/mol
LogP11.97
Rot. Bonds7

About 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine

5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine (PubChem CID 160667879) has the molecular formula C62H60Cl2F5N23O and a molecular weight of 1309.22 g/mol. Its IUPAC name is 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine.

Molecular Properties

Compound Name5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine
PubChem CID160667879
Molecular FormulaC62H60Cl2F5N23O
Molecular Weight1309.22 g/mol
Exact Mass1307.46
IUPAC Name5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine
SMILESCC(C)n1c(N)nc2ccc(C(F)(F)F)nc21.Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cc1.Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cn1.Nc1nc2ccc(N3CCOCC3)nc2n1C1CCC1
InChIInChI=1S/C15H15N5.C14H19N5O.C12H8ClFN4.C11H7ClFN5.C10H11F3N4/c16-15-19-13-7-6-12(10-3-2-8-17-9-10)18-14(13)20(15)11-4-1-5-11;15-14-16-11-4-5-12(18-6-8-20-9-7-18)17-13(11)19(14)10-2-1-3-10;13-10-6-5-9-11(17-10)18(12(15)16-9)8-3-1-7(14)2-4-8;12-8-3-2-7-10(17-8)18(11(14)16-7)9-4-1-6(13)5-15-9;1-5(2)17-8-6(15-9(17)14)3-4-7(16-8)10(11,12)13/h2-3,6-9,11H,1,4-5H2,(H2,16,19);4-5,10H,1-3,6-9H2,(H2,15,16);1-6H,(H2,15,16);1-5H,(H2,14,16);3-5H,1-2H3,(H2,14,15)
InChIKeyRMNVYOSISNQXSI-UHFFFAOYSA-N
XLogP11.97
TPSA321.90 Ų
H-Bond Donors5
H-Bond Acceptors24
Rotatable Bonds7
Heavy Atoms93
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001309.22
LogP ≤ 511.97
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1024

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-[6-[[1-[5-[[7-[4-(4-chloro-1-methylimidazol-2-yl)phenyl]-1-(2-propan-2-yl-3-pyridinyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl]methyl]-2-propan-2-yl-3-pyridinyl]-7-[4-[1-(2-methoxyethyl)pyrazol-4-yl]phenyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl]methyl]-2-propan-2-yl-3-pyridinyl]-3,5-dimethyl-7-[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine
CID 154970495
(8S)-3,8-dimethyl-1-[6-[[(8R)-8-methyl-1-[6-[[8-methyl-7-[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]-1-(2-propan-2-yl-3-pyridinyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl]methyl]-2-propan-2-yl-3-pyridinyl]-7-[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl]methyl]-2-propan-2-yl-3-pyridinyl]-7-[5-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]-2-pyridinyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine
CID 154970541
7-[5-chloro-6-[(2S,6R)-6-[3-methyl-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridin-2-yl]piperidin-2-yl]-3-pyridinyl]-2-[(2R,6S)-6-[5-[2-[(2R,6S)-6-(3-chloro-2-pyridinyl)piperidin-2-yl]-3-fluoro-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridin-7-yl]-3-methyl-2-pyridinyl]piperidin-2-yl]-3-fluoro-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine
CID 156281651
2-[(2R,6S)-6-[4-[3-chloro-2-[(2R,6S)-6-(3-chloro-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-propan-2-ylpiperazin-1-yl)imidazo[1,2-a]pyridin-7-yl]-3-(trifluoromethyl)-2-pyridinyl]-1-methylpiperidin-2-yl]-3-fluoro-7-[6-[(2S,6R)-6-[3-(methoxymethyl)-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridin-2-yl]-1-methylpiperidin-2-yl]-5-(trifluoromethyl)-3-pyridinyl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine
CID 156281653
2-[(2R,6S)-6-(3-chloro-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;2-[(2R,6S)-1-methyl-6-(3-methyl-2-pyridinyl)piperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;2-[(2R,6S)-1-methyl-6-(3-methyl-2-pyridinyl)piperidin-2-yl]-5-(4-methylpiperazin-1-yl)-3-(trifluoromethoxymethyl)imidazo[1,2-a]pyridine;2-[(2R,6S)-1-methyl-6-(3-methyl-2-pyridinyl)piperidin-2-yl]-3-[(1-methylpiperidin-4-ylidene)methyl]imidazo[1,2-a]pyridine
CID 157221422
N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide
CID 157239805
2-[[5-Chloro-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-(1,1-difluoroethyl)-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[6-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone
CID 157279779
5-[2-Cyclobutyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;5-[2-cyclopentyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;5-[2-ethyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;bis(3-methyl-5-[2-(2-methylpropyl)-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]pyridin-2-amine);4-[3-[2-(2-methylpropyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine
CID 157320784
2-(2-aminopyrimidin-5-yl)-N-cyclopropyl-N-ethyl-6,6-dimethyl-8,9-dihydropurino[8,9-c][1,4]oxazin-4-amine;5-[4-(2-azabicyclo[2.1.1]hexan-2-yl)-6,6-dimethyl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl]-3-chloropyridin-2-amine;5-[(6R)-4-(2-azabicyclo[2.1.1]hexan-2-yl)-6-methyl-8,9-dihydro-6H-purino[8,9-c][1,4]oxazin-2-yl]pyrimidin-2-amine;5-[6,6-dimethyl-4-[3-(trifluoromethyl)pyrrolidin-1-yl]-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl]pyrimidin-2-amine
CID 157420230
9-[[3,5-Difluoro-4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7-methyl-2-(2-propan-2-yl-3-pyridinyl)purin-8-one;9-[[3-fluoro-4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7-methyl-2-(2-propan-2-yl-3-pyridinyl)purin-8-one;methane;7-methyl-9-[[4-[1-(oxetan-3-yl)-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-propan-2-yl-3-pyridinyl)purin-8-one
CID 157615684
5-chloro-N-(4,4-dimethylpent-1-en-2-yl)-3-(2-methylpropyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-N-(4-methylpent-1-en-2-yl)-3-(2-methylpropyl)imidazo[4,5-b]pyridin-2-amine;N-[5-chloro-3-(2-methylpropyl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide
CID 157638239
4-[2-(5,10-Dimethyl-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-8-yl)ethyl]morpholine;4-[2-(5,10-dimethyl-4,8,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-8-yl)ethyl]morpholine;4-[2-(6,11-dimethyl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-8-yl)ethyl]morpholine;4-[2-(12-fluoro-6,11-dimethyl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,5,9,11-hexaen-8-yl)ethyl]morpholine;methane;4-[2-(6-methyl-5,8,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-8-yl)ethyl]morpholine;8-(2-morpholin-4-ylethyl)-10-(trifluoromethyl)-8,11-diaza-5-azoniatricyclo[7.4.0.02,7]trideca-1,3,6,9,12-pentaene 5-oxide;hydrochloride
CID 157641158

Frequently Asked Questions

What is the IUPAC name of 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine?
The IUPAC name of 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine (CID 160667879) is 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine.
What is the SMILES notation for 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine?
The canonical SMILES for 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine is CC(C)n1c(N)nc2ccc(C(F)(F)F)nc21.Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cc1.Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cn1.Nc1nc2ccc(N3CCOCC3)nc2n1C1CCC1.
What is the InChIKey of 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine?
The InChIKey is RMNVYOSISNQXSI-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H15N5.C14H19N5O.C12H8ClFN4.C11H7ClFN5.C10H11F3N4/c16-15-19-13-7-6-12(10-3-2-8-17-9-10)18-14(13)20(15)11-4-1-5-11;15-14-16-11-4-5-12(18-6-8-20-9-7-18)17-13(11)19(14)10-2-1-3-10;13-10-6-5-9-11(17-10)18(12(15)16-9)8-3-1-7(14)2-4-8;12-8-3-2-7-10(17-8)18(11(14)16-7)9-4-1-6(13)5-15-9;1-5(2)17-8-6(15-9(17)14)3-4-7(16-8)10(11,12)13/h2-3,6-9,11H,1,4-5H2,(H2,16,19);4-5,10H,1-3,6-9H2,(H2,15,16);1-6H,(H2,15,16);1-5H,(H2,14,16);3-5H,1-2H3,(H2,14,15).
What are the key properties of 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine?
5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine has a molecular weight of 1309.22 g/mol, XLogP of 11.97, 7 rotatable bonds, 5 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-amine;5-chloro-3-(5-fluoro-2-pyridinyl)imidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-morpholin-4-ylimidazo[4,5-b]pyridin-2-amine;3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-amine;3-propan-2-yl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-amine is sourced from PubChem (CID 160667879), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).