N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride

C118H156Cl7F3N28O15 — CID 160693546

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride (PubChem CID 160693546) has the molecular formula C118H156Cl7F3N28O15 and a molecular weight of 2511.89 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride
• PubChem CID: 160693546
• Molecular Formula: C118H156Cl7F3N28O15
• Molecular Weight: 2511.89 g/mol
• Exact Mass: 2507.01
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride
• SMILES: CC(C)Oc1ccc2nc(NC(=O)CCOC(C)(C)C)n(CC(F)(F)F)c2n1.CC1(C)CC[C@@H](CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)O1.CCCn1c(NC(=O)CCC2CCCC2)nc2ccc(Cl)nc21.COC(=O)CCn1c(NC(=O)CC(C)(C)C)nc2ccc(Cl)nc21.COCCn1c(NC(=O)CC(C)(C)C)nc2ccc(Cl)nc21.Cl.O=C(CCC1CCCO1)Nc1nc2ccc(Cl)nc2n1C1CCC1.O=C(CCC1CCOC1)Nc1nc2ccc(Cl)nc2n1C1CCC1
• InChI: InChI=1S/C18H23ClN4O2.C18H25F3N4O3.2C17H21ClN4O2.C17H23ClN4O.C16H21ClN4O3.C15H21ClN4O2.ClH/c1-18(2)9-8-12(25-18)10-15(24)22-17-20-13-6-7-14(19)21-16(13)23(17)11-4-3-5-11;1-11(2)28-14-7-6-12-15(24-14)25(10-18(19,20)21)16(22-12)23-13(26)8-9-27-17(3,4)5;18-14-8-7-13-16(20-14)22(11-3-1-4-11)17(19-13)21-15(23)9-6-12-5-2-10-24-12;18-14-6-5-13-16(20-14)22(12-2-1-3-12)17(19-13)21-15(23)7-4-11-8-9-24-10-11;1-2-11-22-16-13(8-9-14(18)20-16)19-17(22)21-15(23)10-7-12-5-3-4-6-12;1-16(2,3)9-12(22)20-15-18-10-5-6-11(17)19-14(10)21(15)8-7-13(23)24-4;1-15(2,3)9-12(21)19-14-17-10-5-6-11(16)18-13(10)20(14)7-8-22-4;/h6-7,11-12H,3-5,8-10H2,1-2H3,(H,20,22,24);6-7,11H,8-10H2,1-5H3,(H,22,23,26);7-8,11-12H,1-6,9-10H2,(H,19,21,23);5-6,11-12H,1-4,7-10H2,(H,19,21,23);8-9,12H,2-7,10-11H2,1H3,(H,19,21,23);5-6H,7-9H2,1-4H3,(H,18,20,22);5-6H,7-9H2,1-4H3,(H,17,19,21);1H/t12-;;;;;;;/m0......./s1
• InChIKey: DFSNHHXKAWSGLJ-WCCSWWSPSA-N
• XLogP: 26.25
• TPSA: 500.35 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 36
• Rotatable Bonds: 37
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2511.89
LogP ≤ 5	26.25
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	36

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride (CID 160693546) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride is CC(C)Oc1ccc2nc(NC(=O)CCOC(C)(C)C)n(CC(F)(F)F)c2n1.CC1(C)CC[C@@H](CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)O1.CCCn1c(NC(=O)CCC2CCCC2)nc2ccc(Cl)nc21.COC(=O)CCn1c(NC(=O)CC(C)(C)C)nc2ccc(Cl)nc21.COCCn1c(NC(=O)CC(C)(C)C)nc2ccc(Cl)nc21.Cl.O=C(CCC1CCCO1)Nc1nc2ccc(Cl)nc2n1C1CCC1.O=C(CCC1CCOC1)Nc1nc2ccc(Cl)nc2n1C1CCC1.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride?

The InChIKey is DFSNHHXKAWSGLJ-WCCSWWSPSA-N. The full InChI is InChI=1S/C18H23ClN4O2.C18H25F3N4O3.2C17H21ClN4O2.C17H23ClN4O.C16H21ClN4O3.C15H21ClN4O2.ClH/c1-18(2)9-8-12(25-18)10-15(24)22-17-20-13-6-7-14(19)21-16(13)23(17)11-4-3-5-11;1-11(2)28-14-7-6-12-15(24-14)25(10-18(19,20)21)16(22-12)23-13(26)8-9-27-17(3,4)5;18-14-8-7-13-16(20-14)22(11-3-1-4-11)17(19-13)21-15(23)9-6-12-5-2-10-24-12;18-14-6-5-13-16(20-14)22(12-2-1-3-12)17(19-13)21-15(23)7-4-11-8-9-24-10-11;1-2-11-22-16-13(8-9-14(18)20-16)19-17(22)21-15(23)10-7-12-5-3-4-6-12;1-16(2,3)9-12(22)20-15-18-10-5-6-11(17)19-14(10)21(15)8-7-13(23)24-4;1-15(2,3)9-12(21)19-14-17-10-5-6-11(16)18-13(10)20(14)7-8-22-4;/h6-7,11-12H,3-5,8-10H2,1-2H3,(H,20,22,24);6-7,11H,8-10H2,1-5H3,(H,22,23,26);7-8,11-12H,1-6,9-10H2,(H,19,21,23);5-6,11-12H,1-4,7-10H2,(H,19,21,23);8-9,12H,2-7,10-11H2,1H3,(H,19,21,23);5-6H,7-9H2,1-4H3,(H,18,20,22);5-6H,7-9H2,1-4H3,(H,17,19,21);1H/t12-;;;;;;;/m0......./s1.

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride has a molecular weight of 2511.89 g/mol, XLogP of 26.25, 37 rotatable bonds, 7 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-[(2S)-5,5-dimethyloxolan-2-yl]acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-2-yl)propanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-(oxolan-3-yl)propanamide;N-[5-chloro-3-(2-methoxyethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-cyclopentylpropanamide;methyl 3-[5-chloro-2-(3,3-dimethylbutanoylamino)imidazo[4,5-b]pyridin-3-yl]propanoate;3-[(2-methylpropan-2-yl)oxy]-N-[5-propan-2-yloxy-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]propanamide;hydrochloride is sourced from PubChem (CID 160693546), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).