N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide

C291H370Cl2F16N60O32 — CID 158471211

IUPACN-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide
SMILESCC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1C(C)(C)C.CC(C)(O)c1ccc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C(C)(C)C)c2n1.CC(CF)(CF)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.CC1(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2-c2ccc(OC(F)(F)F)cc2)CCC1.CCC(C)(O)CC(=O)Nc1nc2cc(C)c(C)nc2n1C(C)(C)C.CCC(C)(O)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.CCC(C)(O)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(C)(C)C)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OCC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(O)CF)n(-c3ccc(F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(-c3ccc(OC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C3(C)CCC3)c2n1
InChIInChI=1S/C23H25F3N4O3.C23H30N4O3.C23H30N4O2.C22H25F3N4O3.C21H21F3N4O2.C21H23F3N4O2.C19H26N4O2.C18H18F2N4O2.C18H28N4O3.C18H26N4O2.C18H28N4O2.C18H26N4O.C17H24N4O2.C16H19ClF2N4O.C16H21ClN4O2/c1-21(2,32)17-10-9-16-19(28-17)30(14-5-7-15(8-6-14)33-23(24,25)26)20(27-16)29-18(31)13-22(3)11-4-12-22;1-21(2,3)27-19-16(12-13-17(25-19)22(4,5)29)24-20(27)26-18(28)14-23(6,30)15-10-8-7-9-11-15;1-15-8-13-18-20(24-15)27(21(25-18)26-19(28)14-22(2,3)4)16-9-11-17(12-10-16)29-23(5,6)7;1-20(2,3)12-17(30)28-19-26-15-10-11-16(21(4,5)31)27-18(15)29(19)13-6-8-14(9-7-13)32-22(23,24)25;1-13-4-9-16-18(25-13)28(14-5-7-15(8-6-14)30-21(22,23)24)19(26-16)27-17(29)12-20(2)10-3-11-20;1-13-5-10-16-18(25-13)28(19(26-16)27-17(29)11-20(2,3)4)14-6-8-15(9-7-14)30-12-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-11-3-8-14-16(21-11)24(13-6-4-12(20)5-7-13)17(22-14)23-15(25)9-18(2,26)10-19;1-16(2,3)22-14-11(8-9-12(20-14)18(6,7)25)19-15(22)21-13(23)10-17(4,5)24;1-11-6-9-13-15(19-11)22(17(2,3)4)16(20-13)21-14(23)10-18(5,24)12-7-8-12;1-8-18(7,24)10-14(23)21-16-20-13-9-11(2)12(3)19-15(13)22(16)17(4,5)6;1-12-7-8-13-15(19-12)22(17(2,3)4)16(20-13)21-14(23)11-18(5)9-6-10-18;1-4-17(3,23)10-14(22)20-16-19-13-9-8-11(2)18-15(13)21(16)12-6-5-7-12;1-16(8-18,9-19)7-13(24)22-15-20-11-5-6-12(17)21-14(11)23(15)10-3-2-4-10;1-3-16(2,23)9-13(22)20-15-18-11-7-8-12(17)19-14(11)21(15)10-5-4-6-10/h5-10,32H,4,11-13H2,1-3H3,(H,27,29,31);7-13,29-30H,14H2,1-6H3,(H,24,26,28);8-13H,14H2,1-7H3,(H,25,26,28);6-11,31H,12H2,1-5H3,(H,26,28,30);4-9H,3,10-12H2,1-2H3,(H,26,27,29);5-10H,11-12H2,1-4H3,(H,26,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);3-8,26H,9-10H2,1-2H3,(H,22,23,25);8-9,24-25H,10H2,1-7H3,(H,19,21,23);6,9,12,24H,7-8,10H2,1-5H3,(H,20,21,23);9,24H,8,10H2,1-7H3,(H,20,21,23);7-8H,6,9-11H2,1-5H3,(H,20,21,23);8-9,12,23H,4-7,10H2,1-3H3,(H,19,20,22);5-6,10H,2-4,7-9H2,1H3,(H,20,22,24);7-8,10,23H,3-6,9H2,1-2H3,(H,18,20,22)/t;23-;;;;;19-;;;18-;;;;;/m.0....1..1...../s1
InChIKeyHGJICYAYPFUMKU-GWPLOSLGSA-N
MW5595.42 g/mol
LogP58.29
Rot. Bonds71

About N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide

N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide (PubChem CID 158471211) has the molecular formula C291H370Cl2F16N60O32 and a molecular weight of 5595.42 g/mol. Its IUPAC name is N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide.

Molecular Properties

Compound NameN-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide
PubChem CID158471211
Molecular FormulaC291H370Cl2F16N60O32
Molecular Weight5595.42 g/mol
Exact Mass5590.83
IUPAC NameN-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide
SMILESCC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1C(C)(C)C.CC(C)(O)c1ccc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C(C)(C)C)c2n1.CC(CF)(CF)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.CC1(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2-c2ccc(OC(F)(F)F)cc2)CCC1.CCC(C)(O)CC(=O)Nc1nc2cc(C)c(C)nc2n1C(C)(C)C.CCC(C)(O)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.CCC(C)(O)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(C)(C)C)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OCC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(O)CF)n(-c3ccc(F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(-c3ccc(OC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C3(C)CCC3)c2n1
InChIInChI=1S/C23H25F3N4O3.C23H30N4O3.C23H30N4O2.C22H25F3N4O3.C21H21F3N4O2.C21H23F3N4O2.C19H26N4O2.C18H18F2N4O2.C18H28N4O3.C18H26N4O2.C18H28N4O2.C18H26N4O.C17H24N4O2.C16H19ClF2N4O.C16H21ClN4O2/c1-21(2,32)17-10-9-16-19(28-17)30(14-5-7-15(8-6-14)33-23(24,25)26)20(27-16)29-18(31)13-22(3)11-4-12-22;1-21(2,3)27-19-16(12-13-17(25-19)22(4,5)29)24-20(27)26-18(28)14-23(6,30)15-10-8-7-9-11-15;1-15-8-13-18-20(24-15)27(21(25-18)26-19(28)14-22(2,3)4)16-9-11-17(12-10-16)29-23(5,6)7;1-20(2,3)12-17(30)28-19-26-15-10-11-16(21(4,5)31)27-18(15)29(19)13-6-8-14(9-7-13)32-22(23,24)25;1-13-4-9-16-18(25-13)28(14-5-7-15(8-6-14)30-21(22,23)24)19(26-16)27-17(29)12-20(2)10-3-11-20;1-13-5-10-16-18(25-13)28(19(26-16)27-17(29)11-20(2,3)4)14-6-8-15(9-7-14)30-12-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-11-3-8-14-16(21-11)24(13-6-4-12(20)5-7-13)17(22-14)23-15(25)9-18(2,26)10-19;1-16(2,3)22-14-11(8-9-12(20-14)18(6,7)25)19-15(22)21-13(23)10-17(4,5)24;1-11-6-9-13-15(19-11)22(17(2,3)4)16(20-13)21-14(23)10-18(5,24)12-7-8-12;1-8-18(7,24)10-14(23)21-16-20-13-9-11(2)12(3)19-15(13)22(16)17(4,5)6;1-12-7-8-13-15(19-12)22(17(2,3)4)16(20-13)21-14(23)11-18(5)9-6-10-18;1-4-17(3,23)10-14(22)20-16-19-13-9-8-11(2)18-15(13)21(16)12-6-5-7-12;1-16(8-18,9-19)7-13(24)22-15-20-11-5-6-12(17)21-14(11)23(15)10-3-2-4-10;1-3-16(2,23)9-13(22)20-15-18-11-7-8-12(17)19-14(11)21(15)10-5-4-6-10/h5-10,32H,4,11-13H2,1-3H3,(H,27,29,31);7-13,29-30H,14H2,1-6H3,(H,24,26,28);8-13H,14H2,1-7H3,(H,25,26,28);6-11,31H,12H2,1-5H3,(H,26,28,30);4-9H,3,10-12H2,1-2H3,(H,26,27,29);5-10H,11-12H2,1-4H3,(H,26,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);3-8,26H,9-10H2,1-2H3,(H,22,23,25);8-9,24-25H,10H2,1-7H3,(H,19,21,23);6,9,12,24H,7-8,10H2,1-5H3,(H,20,21,23);9,24H,8,10H2,1-7H3,(H,20,21,23);7-8H,6,9-11H2,1-5H3,(H,20,21,23);8-9,12,23H,4-7,10H2,1-3H3,(H,19,20,22);5-6,10H,2-4,7-9H2,1H3,(H,20,22,24);7-8,10,23H,3-6,9H2,1-2H3,(H,18,20,22)/t;23-;;;;;19-;;;18-;;;;;/m.0....1..1...../s1
InChIKeyHGJICYAYPFUMKU-GWPLOSLGSA-N
XLogP58.29
TPSA1186.06 Ų
H-Bond Donors27
H-Bond Acceptors77
Rotatable Bonds71
Heavy Atoms401
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005595.42
LogP ≤ 558.29
H-Bond Donors ≤ 527
H-Bond Acceptors ≤ 1077

Analyze N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide?
The IUPAC name of N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide (CID 158471211) is N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide.
What is the SMILES notation for N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide?
The canonical SMILES for N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide is CC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1C(C)(C)C.CC(C)(O)c1ccc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C(C)(C)C)c2n1.CC(CF)(CF)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.CC1(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2-c2ccc(OC(F)(F)F)cc2)CCC1.CCC(C)(O)CC(=O)Nc1nc2cc(C)c(C)nc2n1C(C)(C)C.CCC(C)(O)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.CCC(C)(O)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(C)(C)C)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OCC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(O)CF)n(-c3ccc(F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(-c3ccc(OC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C3(C)CCC3)c2n1.
What is the InChIKey of N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide?
The InChIKey is HGJICYAYPFUMKU-GWPLOSLGSA-N. The full InChI is InChI=1S/C23H25F3N4O3.C23H30N4O3.C23H30N4O2.C22H25F3N4O3.C21H21F3N4O2.C21H23F3N4O2.C19H26N4O2.C18H18F2N4O2.C18H28N4O3.C18H26N4O2.C18H28N4O2.C18H26N4O.C17H24N4O2.C16H19ClF2N4O.C16H21ClN4O2/c1-21(2,32)17-10-9-16-19(28-17)30(14-5-7-15(8-6-14)33-23(24,25)26)20(27-16)29-18(31)13-22(3)11-4-12-22;1-21(2,3)27-19-16(12-13-17(25-19)22(4,5)29)24-20(27)26-18(28)14-23(6,30)15-10-8-7-9-11-15;1-15-8-13-18-20(24-15)27(21(25-18)26-19(28)14-22(2,3)4)16-9-11-17(12-10-16)29-23(5,6)7;1-20(2,3)12-17(30)28-19-26-15-10-11-16(21(4,5)31)27-18(15)29(19)13-6-8-14(9-7-13)32-22(23,24)25;1-13-4-9-16-18(25-13)28(14-5-7-15(8-6-14)30-21(22,23)24)19(26-16)27-17(29)12-20(2)10-3-11-20;1-13-5-10-16-18(25-13)28(19(26-16)27-17(29)11-20(2,3)4)14-6-8-15(9-7-14)30-12-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-11-3-8-14-16(21-11)24(13-6-4-12(20)5-7-13)17(22-14)23-15(25)9-18(2,26)10-19;1-16(2,3)22-14-11(8-9-12(20-14)18(6,7)25)19-15(22)21-13(23)10-17(4,5)24;1-11-6-9-13-15(19-11)22(17(2,3)4)16(20-13)21-14(23)10-18(5,24)12-7-8-12;1-8-18(7,24)10-14(23)21-16-20-13-9-11(2)12(3)19-15(13)22(16)17(4,5)6;1-12-7-8-13-15(19-12)22(17(2,3)4)16(20-13)21-14(23)11-18(5)9-6-10-18;1-4-17(3,23)10-14(22)20-16-19-13-9-8-11(2)18-15(13)21(16)12-6-5-7-12;1-16(8-18,9-19)7-13(24)22-15-20-11-5-6-12(17)21-14(11)23(15)10-3-2-4-10;1-3-16(2,23)9-13(22)20-15-18-11-7-8-12(17)19-14(11)21(15)10-5-4-6-10/h5-10,32H,4,11-13H2,1-3H3,(H,27,29,31);7-13,29-30H,14H2,1-6H3,(H,24,26,28);8-13H,14H2,1-7H3,(H,25,26,28);6-11,31H,12H2,1-5H3,(H,26,28,30);4-9H,3,10-12H2,1-2H3,(H,26,27,29);5-10H,11-12H2,1-4H3,(H,26,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);3-8,26H,9-10H2,1-2H3,(H,22,23,25);8-9,24-25H,10H2,1-7H3,(H,19,21,23);6,9,12,24H,7-8,10H2,1-5H3,(H,20,21,23);9,24H,8,10H2,1-7H3,(H,20,21,23);7-8H,6,9-11H2,1-5H3,(H,20,21,23);8-9,12,23H,4-7,10H2,1-3H3,(H,19,20,22);5-6,10H,2-4,7-9H2,1H3,(H,20,22,24);7-8,10,23H,3-6,9H2,1-2H3,(H,18,20,22)/t;23-;;;;;19-;;;18-;;;;;/m.0....1..1...../s1.
What are the key properties of N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide?
N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide has a molecular weight of 5595.42 g/mol, XLogP of 58.29, 71 rotatable bonds, 27 hydrogen bond donors, and 77 hydrogen bond acceptors.
Where does this data come from?
All data for N-(3-tert-butyl-5,6-dimethylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;(3S)-N-[3-tert-butyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-4-fluoro-3-(fluoromethyl)-3-methylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylpentanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;4-fluoro-N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]acetamide is sourced from PubChem (CID 158471211), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).