N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride

C108H143Cl3F3N25O7 — CID 160710304

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride (PubChem CID 160710304) has the molecular formula C108H143Cl3F3N25O7 and a molecular weight of 2066.85 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride
• PubChem CID: 160710304
• Molecular Formula: C108H143Cl3F3N25O7
• Molecular Weight: 2066.85 g/mol
• Exact Mass: 2064.06
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride
• SMILES: C#Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.CC(C)(C)CC(=O)Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.CC(C)(C)OCC(C)(C)C(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.CCC(CC)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1cc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2nc1Cl.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cl
• InChI: InChI=1S/C21H25N5O.C19H27ClN4O2.C18H22N4O.C18H26N4O.C17H24N4O.C15H18ClF3N4O.ClH/c1-21(2,3)12-18(27)25-20-24-17-10-9-16(14-6-5-11-22-13-14)23-19(17)26(20)15-7-4-8-15;1-18(2,3)26-11-19(4,5)16(25)23-17-21-13-9-10-14(20)22-15(13)24(17)12-7-6-8-12;1-5-12-9-10-14-16(19-12)22(13-7-6-8-13)17(20-14)21-15(23)11-18(2,3)4;1-4-13(5-2)11-16(23)21-18-20-15-10-9-12(3)19-17(15)22(18)14-7-6-8-14;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-8-5-9-12(22-11(8)16)23(7-15(17,18)19)13(20-9)21-10(24)6-14(2,3)4;/h5-6,9-11,13,15H,4,7-8,12H2,1-3H3,(H,24,25,27);9-10,12H,6-8,11H2,1-5H3,(H,21,23,25);1,9-10,13H,6-8,11H2,2-4H3,(H,20,21,23);9-10,13-14H,4-8,11H2,1-3H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);5H,6-7H2,1-4H3,(H,20,21,24);1H
• InChIKey: RHBGOOMNGJYWNQ-UHFFFAOYSA-N
• XLogP: 25.52
• TPSA: 380.98 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 26
• Rotatable Bonds: 24
• Heavy Atoms: 146
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2066.85
LogP ≤ 5	25.52
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride (CID 160710304) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride is C#Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.CC(C)(C)CC(=O)Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.CC(C)(C)OCC(C)(C)C(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.CCC(CC)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1cc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2nc1Cl.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cl.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride?

The InChIKey is RHBGOOMNGJYWNQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H25N5O.C19H27ClN4O2.C18H22N4O.C18H26N4O.C17H24N4O.C15H18ClF3N4O.ClH/c1-21(2,3)12-18(27)25-20-24-17-10-9-16(14-6-5-11-22-13-14)23-19(17)26(20)15-7-4-8-15;1-18(2,3)26-11-19(4,5)16(25)23-17-21-13-9-10-14(20)22-15(13)24(17)12-7-6-8-12;1-5-12-9-10-14-16(19-12)22(13-7-6-8-13)17(20-14)21-15(23)11-18(2,3)4;1-4-13(5-2)11-16(23)21-18-20-15-10-9-12(3)19-17(15)22(18)14-7-6-8-14;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-8-5-9-12(22-11(8)16)23(7-15(17,18)19)13(20-9)21-10(24)6-14(2,3)4;/h5-6,9-11,13,15H,4,7-8,12H2,1-3H3,(H,24,25,27);9-10,12H,6-8,11H2,1-5H3,(H,21,23,25);1,9-10,13H,6-8,11H2,2-4H3,(H,20,21,23);9-10,13-14H,4-8,11H2,1-3H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);5H,6-7H2,1-4H3,(H,20,21,24);1H.

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride has a molecular weight of 2066.85 g/mol, XLogP of 25.52, 24 rotatable bonds, 6 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-chloro-6-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-ethynylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethylpentanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;hydrochloride is sourced from PubChem (CID 160710304), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).