1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one

C147H151N39O12 — CID 160730099

About 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one

1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one (PubChem CID 160730099) has the molecular formula C147H151N39O12 and a molecular weight of 2656.09 g/mol. Its IUPAC name is 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one.

Molecular Properties

• Compound Name: 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one
• PubChem CID: 160730099
• Molecular Formula: C147H151N39O12
• Molecular Weight: 2656.09 g/mol
• Exact Mass: 2654.24
• IUPAC Name: 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one
• SMILES: CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5c[nH]c6ncccc56)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5ccc6c(c5)C=NC6)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cn[nH]c5)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cnc6c(c5)C=CC6)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cnc6ccccc6c5)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cnn(C)c5)nc4c32)CC1
• InChI: InChI=1S/C27H26N6O2.2C26H26N6O2.C25H25N7O2.C22H25N7O2.C21H23N7O2/c1-17(34)32-11-9-21(10-12-32)33-26-20(16-31(2)27(33)35)15-29-24-8-7-23(30-25(24)26)19-13-18-5-3-4-6-22(18)28-14-19;1-16(33)31-9-7-21(8-10-31)32-25-20(15-30(2)26(32)34)14-28-23-6-5-22(29-24(23)25)17-3-4-18-12-27-13-19(18)11-17;1-16(33)31-10-8-20(9-11-31)32-25-19(15-30(2)26(32)34)14-28-23-7-6-22(29-24(23)25)18-12-17-4-3-5-21(17)27-13-18;1-15(33)31-10-7-17(8-11-31)32-23-16(14-30(2)25(32)34)12-27-21-6-5-20(29-22(21)23)19-13-28-24-18(19)4-3-9-26-24;1-14(30)28-8-6-17(7-9-28)29-21-16(12-26(2)22(29)31)10-23-19-5-4-18(25-20(19)21)15-11-24-27(3)13-15;1-13(29)27-7-5-16(6-8-27)28-20-15(12-26(2)21(28)30)9-22-18-4-3-17(25-19(18)20)14-10-23-24-11-14/h3-8,13-15,21H,9-12,16H2,1-2H3;3-6,11,13-14,21H,7-10,12,15H2,1-2H3;3-4,6-7,12-14,20H,5,8-11,15H2,1-2H3;3-6,9,12-13,17H,7-8,10-11,14H2,1-2H3,(H,26,28);4-5,10-11,13,17H,6-9,12H2,1-3H3;3-4,9-11,16H,5-8,12H2,1-2H3,(H,23,24)
• InChIKey: RUFKGOWUANHZOU-UHFFFAOYSA-N
• XLogP: 19.85
• TPSA: 531.16 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 31
• Rotatable Bonds: 12
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2656.09
LogP ≤ 5	19.85
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?

The IUPAC name of 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one (CID 160730099) is 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one.

What is the SMILES notation for 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?

The canonical SMILES for 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one is CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5c[nH]c6ncccc56)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5ccc6c(c5)C=NC6)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cn[nH]c5)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cnc6c(c5)C=CC6)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cnc6ccccc6c5)nc4c32)CC1.CC(=O)N1CCC(N2C(=O)N(C)Cc3cnc4ccc(-c5cnn(C)c5)nc4c32)CC1.

What is the InChIKey of 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?

The InChIKey is RUFKGOWUANHZOU-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H26N6O2.2C26H26N6O2.C25H25N7O2.C22H25N7O2.C21H23N7O2/c1-17(34)32-11-9-21(10-12-32)33-26-20(16-31(2)27(33)35)15-29-24-8-7-23(30-25(24)26)19-13-18-5-3-4-6-22(18)28-14-19;1-16(33)31-9-7-21(8-10-31)32-25-20(15-30(2)26(32)34)14-28-23-6-5-22(29-24(23)25)17-3-4-18-12-27-13-19(18)11-17;1-16(33)31-10-8-20(9-11-31)32-25-19(15-30(2)26(32)34)14-28-23-7-6-22(29-24(23)25)18-12-17-4-3-5-21(17)27-13-18;1-15(33)31-10-7-17(8-11-31)32-23-16(14-30(2)25(32)34)12-27-21-6-5-20(29-22(21)23)19-13-28-24-18(19)4-3-9-26-24;1-14(30)28-8-6-17(7-9-28)29-21-16(12-26(2)22(29)31)10-23-19-5-4-18(25-20(19)21)15-11-24-27(3)13-15;1-13(29)27-7-5-16(6-8-27)28-20-15(12-26(2)21(28)30)9-22-18-4-3-17(25-19(18)20)14-10-23-24-11-14/h3-8,13-15,21H,9-12,16H2,1-2H3;3-6,11,13-14,21H,7-10,12,15H2,1-2H3;3-4,6-7,12-14,20H,5,8-11,15H2,1-2H3;3-6,9,12-13,17H,7-8,10-11,14H2,1-2H3,(H,26,28);4-5,10-11,13,17H,6-9,12H2,1-3H3;3-4,9-11,16H,5-8,12H2,1-2H3,(H,23,24).

What are the key properties of 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one?

1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one has a molecular weight of 2656.09 g/mol, XLogP of 19.85, 12 rotatable bonds, 2 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 1-(1-acetylpiperidin-4-yl)-9-(7H-cyclopenta[b]pyridin-3-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-9-(1H-isoindol-5-yl)-3-methyl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1-methylpyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrazol-4-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one;1-(1-acetylpiperidin-4-yl)-3-methyl-9-quinolin-3-yl-4H-pyrimido[5,4-c][1,5]naphthyridin-2-one is sourced from PubChem (CID 160730099), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).