2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide

C103H132N22O6S — CID 160745968

IUPAC2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
SMILESCN(C)C(=O)CN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)CN1C(=O)N(c2ccnc(C#N)n2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C#N)ncn1)C(=O)N2CC1CCC1.CSc1cc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ncn1
InChIInChI=1S/C26H32N6O.C26H35N5OS.C26H34N4O2.C25H31N7O2/c1-30(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)18-31(23-15-22(16-27)28-19-29-23)24(33)32(25)17-20-7-6-8-20;1-29(2)26(21-10-5-4-6-11-21)14-12-25(13-15-26)18-30(22-16-23(33-3)28-19-27-22)24(32)31(25)17-20-8-7-9-20;1-27(2)23(31)19-30-24(32)29(22-13-9-6-10-14-22)20-25(30)15-17-26(18-16-25,28(3)4)21-11-7-5-8-12-21;1-29(2)22(33)17-32-23(34)31(21-10-15-27-20(16-26)28-21)18-24(32)11-13-25(14-12-24,30(3)4)19-8-6-5-7-9-19/h3-5,9-10,15,19-20H,6-8,11-14,17-18H2,1-2H3;4-6,10-11,16,19-20H,7-9,12-15,17-18H2,1-3H3;5-14H,15-20H2,1-4H3;5-10,15H,11-14,17-18H2,1-4H3
InChIKeyRWEQLYIEXADQBT-UHFFFAOYSA-N
MW1806.40 g/mol
LogP15.41
Rot. Bonds21

About 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide

2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide (PubChem CID 160745968) has the molecular formula C103H132N22O6S and a molecular weight of 1806.40 g/mol. Its IUPAC name is 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide.

Molecular Properties

Compound Name2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
PubChem CID160745968
Molecular FormulaC103H132N22O6S
Molecular Weight1806.40 g/mol
Exact Mass1805.04
IUPAC Name2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
SMILESCN(C)C(=O)CN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)CN1C(=O)N(c2ccnc(C#N)n2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C#N)ncn1)C(=O)N2CC1CCC1.CSc1cc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ncn1
InChIInChI=1S/C26H32N6O.C26H35N5OS.C26H34N4O2.C25H31N7O2/c1-30(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)18-31(23-15-22(16-27)28-19-29-23)24(33)32(25)17-20-7-6-8-20;1-29(2)26(21-10-5-4-6-11-21)14-12-25(13-15-26)18-30(22-16-23(33-3)28-19-27-22)24(32)31(25)17-20-8-7-9-20;1-27(2)23(31)19-30-24(32)29(22-13-9-6-10-14-22)20-25(30)15-17-26(18-16-25,28(3)4)21-11-7-5-8-12-21;1-29(2)22(33)17-32-23(34)31(21-10-15-27-20(16-26)28-21)18-24(32)11-13-25(14-12-24,30(3)4)19-8-6-5-7-9-19/h3-5,9-10,15,19-20H,6-8,11-14,17-18H2,1-2H3;4-6,10-11,16,19-20H,7-9,12-15,17-18H2,1-3H3;5-14H,15-20H2,1-4H3;5-10,15H,11-14,17-18H2,1-4H3
InChIKeyRWEQLYIEXADQBT-UHFFFAOYSA-N
XLogP15.41
TPSA272.70 Ų
H-Bond Donors
H-Bond Acceptors19
Rotatable Bonds21
Heavy Atoms132
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001806.40
LogP ≤ 515.41
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1019

Analyze 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

5-[1-(Cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[1-(cyclobutylmethyl)-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;5-[1-(cyclobutylmethyl)-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;1-(cyclobutylmethyl)-8-[ethyl(methyl)amino]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 157399005
2-[1-(Cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-5-methylsulfonylbenzonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-methylsulfonylpyrimidine-4-carbonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;5-[1-(2-methoxyethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
CID 159126198
CID 159927108
CID 159927108
2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
CID 160665633
2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
CID 161955824

Frequently Asked Questions

What is the IUPAC name of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The IUPAC name of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide (CID 160745968) is 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide.
What is the SMILES notation for 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The canonical SMILES for 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide is CN(C)C(=O)CN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)CN1C(=O)N(c2ccnc(C#N)n2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C#N)ncn1)C(=O)N2CC1CCC1.CSc1cc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ncn1.
What is the InChIKey of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The InChIKey is RWEQLYIEXADQBT-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H32N6O.C26H35N5OS.C26H34N4O2.C25H31N7O2/c1-30(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)18-31(23-15-22(16-27)28-19-29-23)24(33)32(25)17-20-7-6-8-20;1-29(2)26(21-10-5-4-6-11-21)14-12-25(13-15-26)18-30(22-16-23(33-3)28-19-27-22)24(32)31(25)17-20-8-7-9-20;1-27(2)23(31)19-30-24(32)29(22-13-9-6-10-14-22)20-25(30)15-17-26(18-16-25,28(3)4)21-11-7-5-8-12-21;1-29(2)22(33)17-32-23(34)31(21-10-15-27-20(16-26)28-21)18-24(32)11-13-25(14-12-24,30(3)4)19-8-6-5-7-9-19/h3-5,9-10,15,19-20H,6-8,11-14,17-18H2,1-2H3;4-6,10-11,16,19-20H,7-9,12-15,17-18H2,1-3H3;5-14H,15-20H2,1-4H3;5-10,15H,11-14,17-18H2,1-4H3.
What are the key properties of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide has a molecular weight of 1806.40 g/mol, XLogP of 15.41, 21 rotatable bonds, 0 hydrogen bond donors, and 19 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide is sourced from PubChem (CID 160745968), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).