2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide

C205H261N43O13S — CID 160665633

IUPAC2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
SMILESCN(C)C(=O)CN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)CN1C(=O)N(c2ccnc(C#N)n2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C#N)ncn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc(C#N)n1)C(=O)N2CC1CCC1.COCCN1C(=O)N(c2cnc(C#N)nc2OC)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(c2ncc(C#N)cn2)CC12CCC(c1ccccc1)(N(C)C)CC2.CSc1cc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ncn1
InChIInChI=1S/C27H35N3O.2C26H32N6O.C26H35N5OS.C26H34N4O2.C25H31N7O2.C25H32N6O3.C24H30N6O2/c1-28(2)27(23-12-5-3-6-13-23)18-16-26(17-19-27)21-29(24-14-7-4-8-15-24)25(31)30(26)20-22-10-9-11-22;1-30(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-31(23-11-16-28-22(17-27)29-23)24(33)32(25)18-20-7-6-8-20;1-30(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)18-31(23-15-22(16-27)28-19-29-23)24(33)32(25)17-20-7-6-8-20;1-29(2)26(21-10-5-4-6-11-21)14-12-25(13-15-26)18-30(22-16-23(33-3)28-19-27-22)24(32)31(25)17-20-8-7-9-20;1-27(2)23(31)19-30-24(32)29(22-13-9-6-10-14-22)20-25(30)15-17-26(18-16-25,28(3)4)21-11-7-5-8-12-21;1-29(2)22(33)17-32-23(34)31(21-10-15-27-20(16-26)28-21)18-24(32)11-13-25(14-12-24,30(3)4)19-8-6-5-7-9-19;1-29(2)25(19-8-6-5-7-9-19)12-10-24(11-13-25)18-30(23(32)31(24)14-15-33-3)20-17-27-21(16-26)28-22(20)34-4;1-28(2)24(20-7-5-4-6-8-20)11-9-23(10-12-24)18-29(22(31)30(23)13-14-32-3)21-26-16-19(15-25)17-27-21/h3-8,12-15,22H,9-11,16-21H2,1-2H3;3-5,9-11,16,20H,6-8,12-15,18-19H2,1-2H3;3-5,9-10,15,19-20H,6-8,11-14,17-18H2,1-2H3;4-6,10-11,16,19-20H,7-9,12-15,17-18H2,1-3H3;5-14H,15-20H2,1-4H3;5-10,15H,11-14,17-18H2,1-4H3;5-9,17H,10-15,18H2,1-4H3;4-8,16-17H,9-14,18H2,1-3H3
InChIKeyRMGJUKISONOJLE-UHFFFAOYSA-N
MW3567.70 g/mol
LogP31.09
Rot. Bonds44

About 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide

2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide (PubChem CID 160665633) has the molecular formula C205H261N43O13S and a molecular weight of 3567.70 g/mol. Its IUPAC name is 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide.

Molecular Properties

Compound Name2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
PubChem CID160665633
Molecular FormulaC205H261N43O13S
Molecular Weight3567.70 g/mol
Exact Mass3565.08
IUPAC Name2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
SMILESCN(C)C(=O)CN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)CN1C(=O)N(c2ccnc(C#N)n2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C#N)ncn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc(C#N)n1)C(=O)N2CC1CCC1.COCCN1C(=O)N(c2cnc(C#N)nc2OC)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(c2ncc(C#N)cn2)CC12CCC(c1ccccc1)(N(C)C)CC2.CSc1cc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ncn1
InChIInChI=1S/C27H35N3O.2C26H32N6O.C26H35N5OS.C26H34N4O2.C25H31N7O2.C25H32N6O3.C24H30N6O2/c1-28(2)27(23-12-5-3-6-13-23)18-16-26(17-19-27)21-29(24-14-7-4-8-15-24)25(31)30(26)20-22-10-9-11-22;1-30(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-31(23-11-16-28-22(17-27)29-23)24(33)32(25)18-20-7-6-8-20;1-30(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)18-31(23-15-22(16-27)28-19-29-23)24(33)32(25)17-20-7-6-8-20;1-29(2)26(21-10-5-4-6-11-21)14-12-25(13-15-26)18-30(22-16-23(33-3)28-19-27-22)24(32)31(25)17-20-8-7-9-20;1-27(2)23(31)19-30-24(32)29(22-13-9-6-10-14-22)20-25(30)15-17-26(18-16-25,28(3)4)21-11-7-5-8-12-21;1-29(2)22(33)17-32-23(34)31(21-10-15-27-20(16-26)28-21)18-24(32)11-13-25(14-12-24,30(3)4)19-8-6-5-7-9-19;1-29(2)25(19-8-6-5-7-9-19)12-10-24(11-13-25)18-30(23(32)31(24)14-15-33-3)20-17-27-21(16-26)28-22(20)34-4;1-28(2)24(20-7-5-4-6-8-20)11-9-23(10-12-24)18-29(22(31)30(23)13-14-32-3)21-26-16-19(15-25)17-27-21/h3-8,12-15,22H,9-11,16-21H2,1-2H3;3-5,9-11,16,20H,6-8,12-15,18-19H2,1-2H3;3-5,9-10,15,19-20H,6-8,11-14,17-18H2,1-2H3;4-6,10-11,16,19-20H,7-9,12-15,17-18H2,1-3H3;5-14H,15-20H2,1-4H3;5-10,15H,11-14,17-18H2,1-4H3;5-9,17H,10-15,18H2,1-4H3;4-8,16-17H,9-14,18H2,1-3H3
InChIKeyRMGJUKISONOJLE-UHFFFAOYSA-N
XLogP31.09
TPSA556.26 Ų
H-Bond Donors
H-Bond Acceptors39
Rotatable Bonds44
Heavy Atoms262
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003567.70
LogP ≤ 531.09
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1039

Analyze 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide with MolForge

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Related Compounds

8-(Dimethylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(methylsulfonylmethyl)phenyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(morpholine-4-carbonyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-morpholin-4-yl-4-(trifluoromethyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;bis(5-[8-(ethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile);methyl 2-[4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]piperazin-1-yl]acetate
CID 160879602
CID 157157125
CID 157157125
5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;N-(cyclobutylmethyl)-5-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-2-oxo-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;5-[8-(dimethylamino)-8-(3-fluorophenyl)-1-methyl-2-oxo-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;5-[1-(3-methoxypropyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
CID 157672073
5-[1-(Cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrazine-2-carbonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrazine-2-carbonitrile
CID 158436340
5-[1-(Cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrazine-2-carbonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
CID 158478385
8-(Dimethylamino)-3-[2-(morpholine-4-carbonyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;bis(5-[8-(ethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile);methyl 2-[4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]piperazin-1-yl]acetate
CID 159265905
1-(Cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile
CID 159805073
CID 159927108
CID 159927108
CID 160295477
CID 160295477
CID 160460456
CID 160460456
CID 160725743
CID 160725743
2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
CID 160745968

Frequently Asked Questions

What is the IUPAC name of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The IUPAC name of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide (CID 160665633) is 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide.
What is the SMILES notation for 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The canonical SMILES for 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide is CN(C)C(=O)CN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)CN1C(=O)N(c2ccnc(C#N)n2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C#N)ncn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc(C#N)n1)C(=O)N2CC1CCC1.COCCN1C(=O)N(c2cnc(C#N)nc2OC)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(c2ncc(C#N)cn2)CC12CCC(c1ccccc1)(N(C)C)CC2.CSc1cc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ncn1.
What is the InChIKey of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The InChIKey is RMGJUKISONOJLE-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H35N3O.2C26H32N6O.C26H35N5OS.C26H34N4O2.C25H31N7O2.C25H32N6O3.C24H30N6O2/c1-28(2)27(23-12-5-3-6-13-23)18-16-26(17-19-27)21-29(24-14-7-4-8-15-24)25(31)30(26)20-22-10-9-11-22;1-30(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-31(23-11-16-28-22(17-27)29-23)24(33)32(25)18-20-7-6-8-20;1-30(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)18-31(23-15-22(16-27)28-19-29-23)24(33)32(25)17-20-7-6-8-20;1-29(2)26(21-10-5-4-6-11-21)14-12-25(13-15-26)18-30(22-16-23(33-3)28-19-27-22)24(32)31(25)17-20-8-7-9-20;1-27(2)23(31)19-30-24(32)29(22-13-9-6-10-14-22)20-25(30)15-17-26(18-16-25,28(3)4)21-11-7-5-8-12-21;1-29(2)22(33)17-32-23(34)31(21-10-15-27-20(16-26)28-21)18-24(32)11-13-25(14-12-24,30(3)4)19-8-6-5-7-9-19;1-29(2)25(19-8-6-5-7-9-19)12-10-24(11-13-25)18-30(23(32)31(24)14-15-33-3)20-17-27-21(16-26)28-22(20)34-4;1-28(2)24(20-7-5-4-6-8-20)11-9-23(10-12-24)18-29(22(31)30(23)13-14-32-3)21-26-16-19(15-25)17-27-21/h3-8,12-15,22H,9-11,16-21H2,1-2H3;3-5,9-11,16,20H,6-8,12-15,18-19H2,1-2H3;3-5,9-10,15,19-20H,6-8,11-14,17-18H2,1-2H3;4-6,10-11,16,19-20H,7-9,12-15,17-18H2,1-3H3;5-14H,15-20H2,1-4H3;5-10,15H,11-14,17-18H2,1-4H3;5-9,17H,10-15,18H2,1-4H3;4-8,16-17H,9-14,18H2,1-3H3.
What are the key properties of 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide has a molecular weight of 3567.70 g/mol, XLogP of 31.09, 44 rotatable bonds, 0 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(2-cyanopyrimidin-4-yl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(6-methylsulfanylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;6-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-4-carbonitrile;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;2-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;2-[8-(dimethylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide is sourced from PubChem (CID 160665633), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).