2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C77H64F18N30O10 — CID 160825759

IUPAC2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCC(C)Oc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.CCOc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OC1CCC1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCC(F)(F)F
InChIInChI=1S/C17H15F3N6O2.C16H15F3N6O2.C15H10F6N6O2.C15H13F3N6O2.C14H11F3N6O2/c18-17(19,20)12-5-7-26-15(24-12)13(14(21)25-26)16(27)23-10-8-22-6-4-11(10)28-9-2-1-3-9;1-8(2)27-10-3-5-21-7-9(10)22-15(26)12-13(20)24-25-6-4-11(16(17,18)19)23-14(12)25;16-14(17,18)6-29-8-1-3-23-5-7(8)24-13(28)10-11(22)26-27-4-2-9(15(19,20)21)25-12(10)27;1-2-26-9-3-5-20-7-8(9)21-14(25)11-12(19)23-24-6-4-10(15(16,17)18)22-13(11)24;1-25-8-2-4-19-6-7(8)20-13(24)10-11(18)22-23-5-3-9(14(15,16)17)21-12(10)23/h4-9H,1-3H2,(H2,21,25)(H,23,27);3-8H,1-2H3,(H2,20,24)(H,22,26);1-5H,6H2,(H2,22,26)(H,24,28);3-7H,2H2,1H3,(H2,19,23)(H,21,25);2-6H,1H3,(H2,18,22)(H,20,24)
InChIKeySGDHATDYVHMECS-UHFFFAOYSA-N
MW1911.52 g/mol
LogP12.95
Rot. Bonds19

About 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 160825759) has the molecular formula C77H64F18N30O10 and a molecular weight of 1911.52 g/mol. Its IUPAC name is 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID160825759
Molecular FormulaC77H64F18N30O10
Molecular Weight1911.52 g/mol
Exact Mass1910.51
IUPAC Name2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCC(C)Oc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.CCOc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OC1CCC1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCC(F)(F)F
InChIInChI=1S/C17H15F3N6O2.C16H15F3N6O2.C15H10F6N6O2.C15H13F3N6O2.C14H11F3N6O2/c18-17(19,20)12-5-7-26-15(24-12)13(14(21)25-26)16(27)23-10-8-22-6-4-11(10)28-9-2-1-3-9;1-8(2)27-10-3-5-21-7-9(10)22-15(26)12-13(20)24-25-6-4-11(16(17,18)19)23-14(12)25;16-14(17,18)6-29-8-1-3-23-5-7(8)24-13(28)10-11(22)26-27-4-2-9(15(19,20)21)25-12(10)27;1-2-26-9-3-5-20-7-8(9)21-14(25)11-12(19)23-24-6-4-10(15(16,17)18)22-13(11)24;1-25-8-2-4-19-6-7(8)20-13(24)10-11(18)22-23-5-3-9(14(15,16)17)21-12(10)23/h4-9H,1-3H2,(H2,21,25)(H,23,27);3-8H,1-2H3,(H2,20,24)(H,22,26);1-5H,6H2,(H2,22,26)(H,24,28);3-7H,2H2,1H3,(H2,19,23)(H,21,25);2-6H,1H3,(H2,18,22)(H,20,24)
InChIKeySGDHATDYVHMECS-UHFFFAOYSA-N
XLogP12.95
TPSA537.15 Ų
H-Bond Donors10
H-Bond Acceptors35
Rotatable Bonds19
Heavy Atoms135
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001911.52
LogP ≤ 512.95
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1035

Analyze 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

2-amino-N-[4-[[(6S)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76285599
2-amino-6-fluoro-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287697
2-amino-N-[4-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287701
2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287702
2-amino-N-[4-[[(3S)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287848
2-amino-6-fluoro-N-[4-(1-methylpiperidin-4-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287850
5-amino-11-methyl-N-[4-(2,2,2-trifluoroethoxy)pyridin-3-yl]-2,6,7,11-tetrazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraene-4-carboxamide
CID 90409024
2-amino-N-[4-[3-(dimethylamino)propoxy]pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302752
2-amino-N-[4-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302753
2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302754
2-amino-N-[4-(1-methylpiperidin-4-yl)oxypyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302756
2-amino-N-[4-[(3S)-1-(2-methoxyethyl)piperidin-3-yl]oxypyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86304150

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 160825759) is 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is CC(C)Oc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.CCOc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OC1CCC1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCC(F)(F)F.
What is the InChIKey of 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is SGDHATDYVHMECS-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H15F3N6O2.C16H15F3N6O2.C15H10F6N6O2.C15H13F3N6O2.C14H11F3N6O2/c18-17(19,20)12-5-7-26-15(24-12)13(14(21)25-26)16(27)23-10-8-22-6-4-11(10)28-9-2-1-3-9;1-8(2)27-10-3-5-21-7-9(10)22-15(26)12-13(20)24-25-6-4-11(16(17,18)19)23-14(12)25;16-14(17,18)6-29-8-1-3-23-5-7(8)24-13(28)10-11(22)26-27-4-2-9(15(19,20)21)25-12(10)27;1-2-26-9-3-5-20-7-8(9)21-14(25)11-12(19)23-24-6-4-10(15(16,17)18)22-13(11)24;1-25-8-2-4-19-6-7(8)20-13(24)10-11(18)22-23-5-3-9(14(15,16)17)21-12(10)23/h4-9H,1-3H2,(H2,21,25)(H,23,27);3-8H,1-2H3,(H2,20,24)(H,22,26);1-5H,6H2,(H2,22,26)(H,24,28);3-7H,2H2,1H3,(H2,19,23)(H,21,25);2-6H,1H3,(H2,18,22)(H,20,24).
What are the key properties of 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 1911.52 g/mol, XLogP of 12.95, 19 rotatable bonds, 10 hydrogen bond donors, and 35 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-(4-cyclobutyloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-ethoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-propan-2-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(2,2,2-trifluoroethoxy)-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 160825759), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).