N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

C124H114F11N25O11S5 — CID 160993499

About N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (PubChem CID 160993499) has the molecular formula C124H114F11N25O11S5 and a molecular weight of 2499.75 g/mol. Its IUPAC name is N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• PubChem CID: 160993499
• Molecular Formula: C124H114F11N25O11S5
• Molecular Weight: 2499.75 g/mol
• Exact Mass: 2497.76
• IUPAC Name: N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• SMILES: CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ccccc1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ccccn1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(C)n1)n2-c1ncccn1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ccccn1.Cc1ccc(-n2c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)c(C#N)c3cc(F)c(C)cc32)nc1
• InChI: InChI=1S/C26H25FN4O2S.C25H26FN5O3S.C25H24FN5O2S.C24H20F4N6O2S.C24H19F4N5O2S/c1-5-17-13-24-20(14-22(17)27)21(15-28)25(31(24)18-9-7-6-8-10-18)23-12-11-19(16-29-23)34(32,33)30-26(2,3)4;1-5-15-12-20-17(13-18(15)26)22(24(27)32)23(31(20)21-8-6-7-11-28-21)19-10-9-16(14-29-19)35(33,34)30-25(2,3)4;1-5-16-12-22-18(13-20(16)26)19(14-27)24(31(22)23-8-6-7-11-28-23)21-10-9-17(15-29-21)34(32,33)30-25(2,3)4;1-4-15-10-20-16(11-18(15)25)17(12-29)22(34(20)23-30-8-5-9-31-23)19-6-7-21(13(2)32-19)37(35,36)33-14(3)24(26,27)28;1-13-4-7-22(31-11-13)33-21-8-14(2)19(25)9-17(21)18(10-29)23(33)20-6-5-16(12-30-20)36(34,35)32-15(3)24(26,27)28/h6-14,16,30H,5H2,1-4H3;6-14,30H,5H2,1-4H3,(H2,27,32);6-13,15,30H,5H2,1-4H3;5-11,14,33H,4H2,1-3H3;4-9,11-12,15,32H,1-3H3/t;;;14-;15-/m...00/s1
• InChIKey: TUXZXYKYLLZPBP-AWCQGIQVSA-N
• XLogP: 23.58
• TPSA: 522.65 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 30
• Rotatable Bonds: 27
• Heavy Atoms: 176
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2499.75
LogP ≤ 5	23.58
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The IUPAC name of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (CID 160993499) is N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

What is the SMILES notation for N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The canonical SMILES for N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ccccc1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ccccn1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(C)n1)n2-c1ncccn1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ccccn1.Cc1ccc(-n2c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)c(C#N)c3cc(F)c(C)cc32)nc1.

What is the InChIKey of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The InChIKey is TUXZXYKYLLZPBP-AWCQGIQVSA-N. The full InChI is InChI=1S/C26H25FN4O2S.C25H26FN5O3S.C25H24FN5O2S.C24H20F4N6O2S.C24H19F4N5O2S/c1-5-17-13-24-20(14-22(17)27)21(15-28)25(31(24)18-9-7-6-8-10-18)23-12-11-19(16-29-23)34(32,33)30-26(2,3)4;1-5-15-12-20-17(13-18(15)26)22(24(27)32)23(31(20)21-8-6-7-11-28-21)19-10-9-16(14-29-19)35(33,34)30-25(2,3)4;1-5-16-12-22-18(13-20(16)26)19(14-27)24(31(22)23-8-6-7-11-28-23)21-10-9-17(15-29-21)34(32,33)30-25(2,3)4;1-4-15-10-20-16(11-18(15)25)17(12-29)22(34(20)23-30-8-5-9-31-23)19-6-7-21(13(2)32-19)37(35,36)33-14(3)24(26,27)28;1-13-4-7-22(31-11-13)33-21-8-14(2)19(25)9-17(21)18(10-29)23(33)20-6-5-16(12-30-20)36(34,35)32-15(3)24(26,27)28/h6-14,16,30H,5H2,1-4H3;6-14,30H,5H2,1-4H3,(H2,27,32);6-13,15,30H,5H2,1-4H3;5-11,14,33H,4H2,1-3H3;4-9,11-12,15,32H,1-3H3/t;;;14-;15-/m...00/s1.

What are the key properties of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide has a molecular weight of 2499.75 g/mol, XLogP of 23.58, 27 rotatable bonds, 6 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-phenylindol-2-yl)pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-6-ethyl-5-fluoro-1-pyridin-2-ylindole-3-carboxamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-2-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(5-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is sourced from PubChem (CID 160993499), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).