1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

C209H284F4N24O21 — CID 161010042

IUPAC1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccc(C#N)cc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccc(C(F)(F)F)nc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2CC1CCC1.COCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)N(Cc2ccc(OC)cc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COc1ccc(CN2CC3(CCC(c4cccc(F)c4)(N(C)C)CC3)NC2=O)cc1.COc1ccc(CN2CC3(CCC(c4cccc(O)c4)(N(C)C)CC3)N(CC3CCC3)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC3CCOCC3)C2=O)cc1
InChIInChI=1S/C41H65N3O10.C31H43N3O3.C29H36N4O.C29H39N3O3.C28H35F3N4O.C27H36N4O.C24H30FN3O2/c1-42(2)41(37-8-6-5-7-9-37)16-14-40(15-17-41)35-43(34-36-10-12-38(47-4)13-11-36)39(45)44(40)18-19-48-22-23-50-26-27-52-30-31-54-33-32-53-29-28-51-25-24-49-21-20-46-3;1-32(2)31(27-7-5-4-6-8-27)18-16-30(17-19-31)24-33(23-26-9-11-28(36-3)12-10-26)29(35)34(30)20-13-25-14-21-37-22-15-25;1-31(2)29(26-9-4-3-5-10-26)17-15-28(16-18-29)22-32(20-25-13-11-23(19-30)12-14-25)27(34)33(28)21-24-7-6-8-24;1-30(2)29(24-8-5-9-25(33)18-24)16-14-28(15-17-29)21-31(19-23-10-12-26(35-3)13-11-23)27(34)32(28)20-22-6-4-7-22;1-33(2)27(23-9-4-3-5-10-23)15-13-26(14-16-27)20-34(25(36)35(26)19-21-7-6-8-21)18-22-11-12-24(32-17-22)28(29,30)31;1-29(2)27(24-11-4-3-5-12-24)15-13-26(14-16-27)21-30(19-23-10-7-17-28-18-23)25(32)31(26)20-22-8-6-9-22;1-27(2)24(19-5-4-6-20(25)15-19)13-11-23(12-14-24)17-28(22(29)26-23)16-18-7-9-21(30-3)10-8-18/h5-13H,14-35H2,1-4H3;4-12,25H,13-24H2,1-3H3;3-5,9-14,24H,6-8,15-18,20-22H2,1-2H3;5,8-13,18,22,33H,4,6-7,14-17,19-21H2,1-3H3;3-5,9-12,17,21H,6-8,13-16,18-20H2,1-2H3;3-5,7,10-12,17-18,22H,6,8-9,13-16,19-21H2,1-2H3;4-10,15H,11-14,16-17H2,1-3H3,(H,26,29)
InChIKeyTXAADOHHNBHHNQ-UHFFFAOYSA-N
MW3544.71 g/mol
LogP35.49
Rot. Bonds67

About 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 161010042) has the molecular formula C209H284F4N24O21 and a molecular weight of 3544.71 g/mol. Its IUPAC name is 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
PubChem CID161010042
Molecular FormulaC209H284F4N24O21
Molecular Weight3544.71 g/mol
Exact Mass3542.18
IUPAC Name1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccc(C#N)cc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccc(C(F)(F)F)nc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2CC1CCC1.COCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)N(Cc2ccc(OC)cc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COc1ccc(CN2CC3(CCC(c4cccc(F)c4)(N(C)C)CC3)NC2=O)cc1.COc1ccc(CN2CC3(CCC(c4cccc(O)c4)(N(C)C)CC3)N(CC3CCC3)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC3CCOCC3)C2=O)cc1
InChIInChI=1S/C41H65N3O10.C31H43N3O3.C29H36N4O.C29H39N3O3.C28H35F3N4O.C27H36N4O.C24H30FN3O2/c1-42(2)41(37-8-6-5-7-9-37)16-14-40(15-17-41)35-43(34-36-10-12-38(47-4)13-11-36)39(45)44(40)18-19-48-22-23-50-26-27-52-30-31-54-33-32-53-29-28-51-25-24-49-21-20-46-3;1-32(2)31(27-7-5-4-6-8-27)18-16-30(17-19-31)24-33(23-26-9-11-28(36-3)12-10-26)29(35)34(30)20-13-25-14-21-37-22-15-25;1-31(2)29(26-9-4-3-5-10-26)17-15-28(16-18-29)22-32(20-25-13-11-23(19-30)12-14-25)27(34)33(28)21-24-7-6-8-24;1-30(2)29(24-8-5-9-25(33)18-24)16-14-28(15-17-29)21-31(19-23-10-12-26(35-3)13-11-23)27(34)32(28)20-22-6-4-7-22;1-33(2)27(23-9-4-3-5-10-23)15-13-26(14-16-27)20-34(25(36)35(26)19-21-7-6-8-21)18-22-11-12-24(32-17-22)28(29,30)31;1-29(2)27(24-11-4-3-5-12-24)15-13-26(14-16-27)21-30(19-23-10-7-17-28-18-23)25(32)31(26)20-22-8-6-9-22;1-27(2)24(19-5-4-6-20(25)15-19)13-11-23(12-14-24)17-28(22(29)26-23)16-18-7-9-21(30-3)10-8-18/h5-13H,14-35H2,1-4H3;4-12,25H,13-24H2,1-3H3;3-5,9-14,24H,6-8,15-18,20-22H2,1-2H3;5,8-13,18,22,33H,4,6-7,14-17,19-21H2,1-3H3;3-5,9-12,17,21H,6-8,13-16,18-20H2,1-2H3;3-5,7,10-12,17-18,22H,6,8-9,13-16,19-21H2,1-2H3;4-10,15H,11-14,16-17H2,1-3H3,(H,26,29)
InChIKeyTXAADOHHNBHHNQ-UHFFFAOYSA-N
XLogP35.49
TPSA386.11 Ų
H-Bond Donors2
H-Bond Acceptors31
Rotatable Bonds67
Heavy Atoms258
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003544.71
LogP ≤ 535.49
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 1031

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Analyze 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one with MolForge

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Related Compounds

1-(2-Cyclobutylethyl)-8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-[ethyl(methyl)amino]-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;2-[[1-(cyclobutylmethyl)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-8-yl]-methylamino]acetonitrile;1-[(3,3-difluorocyclobutyl)methyl]-8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2,2-dimethylpropyl)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-hydroxyethyl)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(3-methylbutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1-[3-(trifluoromethoxy)propyl]-1,3-diazaspiro[4.5]decan-2-one
CID 157362485
CID 159924297
CID 159924297
CID 160002061
CID 160002061
CID 160080101
CID 160080101
CID 158637937
CID 158637937
1-Butyl-8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[[3-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]phenyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-(4-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(4-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
CID 159695111
CID 159737216
CID 159737216
1-(Cyclobutylmethyl)-8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-[ethyl(methyl)amino]-3-[(3-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[[1-(cyclobutylmethyl)-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-3-[(3-methoxyphenyl)methyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-[(3-methoxyphenyl)methyl]-8-[methyl(propyl)amino]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(methylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxy-2-methylpropyl)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanenitrile
CID 159892125
CID 160639779
CID 160639779
CID 160648880
CID 160648880
N-(cyanomethyl)-2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclohexylmethyl)-8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-ethyl-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;3-[[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]-4-methoxybenzonitrile;8-(dimethylamino)-1-[2-(1-methoxycyclobutyl)ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(oxan-4-ylmethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-phenyl-1-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one
CID 161186205
CID 161340268
CID 161340268

Frequently Asked Questions

What is the IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (CID 161010042) is 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccc(C#N)cc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccc(C(F)(F)F)nc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2CC1CCC1.COCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)N(Cc2ccc(OC)cc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COc1ccc(CN2CC3(CCC(c4cccc(F)c4)(N(C)C)CC3)NC2=O)cc1.COc1ccc(CN2CC3(CCC(c4cccc(O)c4)(N(C)C)CC3)N(CC3CCC3)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC3CCOCC3)C2=O)cc1.
What is the InChIKey of 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is TXAADOHHNBHHNQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C41H65N3O10.C31H43N3O3.C29H36N4O.C29H39N3O3.C28H35F3N4O.C27H36N4O.C24H30FN3O2/c1-42(2)41(37-8-6-5-7-9-37)16-14-40(15-17-41)35-43(34-36-10-12-38(47-4)13-11-36)39(45)44(40)18-19-48-22-23-50-26-27-52-30-31-54-33-32-53-29-28-51-25-24-49-21-20-46-3;1-32(2)31(27-7-5-4-6-8-27)18-16-30(17-19-31)24-33(23-26-9-11-28(36-3)12-10-26)29(35)34(30)20-13-25-14-21-37-22-15-25;1-31(2)29(26-9-4-3-5-10-26)17-15-28(16-18-29)22-32(20-25-13-11-23(19-30)12-14-25)27(34)33(28)21-24-7-6-8-24;1-30(2)29(24-8-5-9-25(33)18-24)16-14-28(15-17-29)21-31(19-23-10-12-26(35-3)13-11-23)27(34)32(28)20-22-6-4-7-22;1-33(2)27(23-9-4-3-5-10-23)15-13-26(14-16-27)20-34(25(36)35(26)19-21-7-6-8-21)18-22-11-12-24(32-17-22)28(29,30)31;1-29(2)27(24-11-4-3-5-12-24)15-13-26(14-16-27)21-30(19-23-10-7-17-28-18-23)25(32)31(26)20-22-8-6-9-22;1-27(2)24(19-5-4-6-20(25)15-19)13-11-23(12-14-24)17-28(22(29)26-23)16-18-7-9-21(30-3)10-8-18/h5-13H,14-35H2,1-4H3;4-12,25H,13-24H2,1-3H3;3-5,9-14,24H,6-8,15-18,20-22H2,1-2H3;5,8-13,18,22,33H,4,6-7,14-17,19-21H2,1-3H3;3-5,9-12,17,21H,6-8,13-16,18-20H2,1-2H3;3-5,7,10-12,17-18,22H,6,8-9,13-16,19-21H2,1-2H3;4-10,15H,11-14,16-17H2,1-3H3,(H,26,29).
What are the key properties of 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 3544.71 g/mol, XLogP of 35.49, 67 rotatable bonds, 2 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(cyclobutylmethyl)-8-(dimethylamino)-8-(3-hydroxyphenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;4-[[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]methyl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[(4-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-[2-(oxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 161010042), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).