2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C94H98F15N35O12 — CID 161012540

About 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 161012540) has the molecular formula C94H98F15N35O12 and a molecular weight of 2195.02 g/mol. Its IUPAC name is 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

• Compound Name: 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
• PubChem CID: 161012540
• Molecular Formula: C94H98F15N35O12
• Molecular Weight: 2195.02 g/mol
• Exact Mass: 2193.79
• IUPAC Name: 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
• SMILES: CN(C)CCOCCOc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.CN1CC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.CN1CC[C@H](Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCC1CCC(N)CC1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCCN1CC2(COC2)C1
• InChI: InChI=1S/C20H20F3N7O3.C20H22F3N7O2.C19H22F3N7O3.C18H18F3N7O2.C17H16F3N7O2/c21-20(22,23)14-2-4-30-17(27-14)15(16(24)28-30)18(31)26-12-7-25-3-1-13(12)33-6-5-29-8-19(9-29)10-32-11-19;21-20(22,23)15-6-8-30-18(28-15)16(17(25)29-30)19(31)27-13-9-26-7-5-14(13)32-10-11-1-3-12(24)4-2-11;1-28(2)7-8-31-9-10-32-13-3-5-24-11-12(13)25-18(30)15-16(23)27-29-6-4-14(19(20,21)22)26-17(15)29;1-27-6-3-10(9-27)30-12-2-5-23-8-11(12)24-17(29)14-15(22)26-28-7-4-13(18(19,20)21)25-16(14)28;1-26-7-9(8-26)29-11-2-4-22-6-10(11)23-16(28)13-14(21)25-27-5-3-12(17(18,19)20)24-15(13)27/h1-4,7H,5-6,8-11H2,(H2,24,28)(H,26,31);5-9,11-12H,1-4,10,24H2,(H2,25,29)(H,27,31);3-6,11H,7-10H2,1-2H3,(H2,23,27)(H,25,30);2,4-5,7-8,10H,3,6,9H2,1H3,(H2,22,26)(H,24,29);2-6,9H,7-8H2,1H3,(H2,21,25)(H,23,28)/t;;;10-;/m...0./s1
• InChIKey: TXHWHWAMUJAYNA-CPKWHSIVSA-N
• XLogP: 10.23
• TPSA: 594.59 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 42
• Rotatable Bonds: 28
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2195.02
LogP ≤ 5	10.23
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The IUPAC name of 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 161012540) is 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

What is the SMILES notation for 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The canonical SMILES for 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is CN(C)CCOCCOc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.CN1CC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.CN1CC[C@H](Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCC1CCC(N)CC1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OCCN1CC2(COC2)C1.

What is the InChIKey of 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The InChIKey is TXHWHWAMUJAYNA-CPKWHSIVSA-N. The full InChI is InChI=1S/C20H20F3N7O3.C20H22F3N7O2.C19H22F3N7O3.C18H18F3N7O2.C17H16F3N7O2/c21-20(22,23)14-2-4-30-17(27-14)15(16(24)28-30)18(31)26-12-7-25-3-1-13(12)33-6-5-29-8-19(9-29)10-32-11-19;21-20(22,23)15-6-8-30-18(28-15)16(17(25)29-30)19(31)27-13-9-26-7-5-14(13)32-10-11-1-3-12(24)4-2-11;1-28(2)7-8-31-9-10-32-13-3-5-24-11-12(13)25-18(30)15-16(23)27-29-6-4-14(19(20,21)22)26-17(15)29;1-27-6-3-10(9-27)30-12-2-5-23-8-11(12)24-17(29)14-15(22)26-28-7-4-13(18(19,20)21)25-16(14)28;1-26-7-9(8-26)29-11-2-4-22-6-10(11)23-16(28)13-14(21)25-27-5-3-12(17(18,19)20)24-15(13)27/h1-4,7H,5-6,8-11H2,(H2,24,28)(H,26,31);5-9,11-12H,1-4,10,24H2,(H2,25,29)(H,27,31);3-6,11H,7-10H2,1-2H3,(H2,23,27)(H,25,30);2,4-5,7-8,10H,3,6,9H2,1H3,(H2,22,26)(H,24,29);2-6,9H,7-8H2,1H3,(H2,21,25)(H,23,28)/t;;;10-;/m...0./s1.

What are the key properties of 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?

2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2195.02 g/mol, XLogP of 10.23, 28 rotatable bonds, 11 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-N-[4-[(4-aminocyclohexyl)methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-[2-(dimethylamino)ethoxy]ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(1-methylazetidin-3-yl)oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 161012540), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).