5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine

C100H88N46OS4 — CID 161019851

About 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine

5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine (PubChem CID 161019851) has the molecular formula C100H88N46OS4 and a molecular weight of 2078.39 g/mol. Its IUPAC name is 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

• Compound Name: 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
• PubChem CID: 161019851
• Molecular Formula: C100H88N46OS4
• Molecular Weight: 2078.39 g/mol
• Exact Mass: 2076.71
• IUPAC Name: 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
• SMILES: CCSc1nnc(Nc2nccn3c(-c4cnn(C)c4)cnc23)s1.COc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cn1cc(-c2cnc3c(Nc4ccc(-n5cncn5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnn4-c4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1
• InChI: InChI=1S/C19H16N8.C18H15N9.C17H13N7S.C17H16N6O.C15H14N8S.C14H14N8S2/c1-25-13-14(11-23-25)16-12-21-19-18(20-9-10-26(16)19)24-17-7-8-22-27(17)15-5-3-2-4-6-15;1-25-10-13(8-22-25)16-9-21-18-17(20-6-7-26(16)18)24-14-2-4-15(5-3-14)27-12-19-11-23-27;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9;1-3-23-14-20-19-13(24-14)18-11-12-16-7-10(22(12)5-4-15-11)9-6-17-21(2)8-9/h2-13H,1H3,(H,20,24);2-12H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21);4-8H,3H2,1-2H3,(H,15,18,19)
• InChIKey: TYFJGNNVCCUHJL-UHFFFAOYSA-N
• XLogP: 17.32
• TPSA: 482.45 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 51
• Rotatable Bonds: 24
• Heavy Atoms: 151
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2078.39
LogP ≤ 5	17.32
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	51

Frequently Asked Questions

What is the IUPAC name of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

The IUPAC name of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine (CID 161019851) is 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine.

What is the SMILES notation for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

The canonical SMILES for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine is CCSc1nnc(Nc2nccn3c(-c4cnn(C)c4)cnc23)s1.COc1ccccc1Nc1nccn2c(-c3cnn(C)c3)cnc12.Cn1cc(-c2cnc3c(Nc4ccc(-n5cncn5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccnn4-c4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc5ccccc5s4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nnc(C5CC5)s4)nccn23)cn1.

What is the InChIKey of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

The InChIKey is TYFJGNNVCCUHJL-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16N8.C18H15N9.C17H13N7S.C17H16N6O.C15H14N8S.C14H14N8S2/c1-25-13-14(11-23-25)16-12-21-19-18(20-9-10-26(16)19)24-17-7-8-22-27(17)15-5-3-2-4-6-15;1-25-10-13(8-22-25)16-9-21-18-17(20-6-7-26(16)18)24-14-2-4-15(5-3-14)27-12-19-11-23-27;1-23-10-11(8-20-23)13-9-19-16-15(18-6-7-24(13)16)22-17-21-12-4-2-3-5-14(12)25-17;1-22-11-12(9-20-22)14-10-19-17-16(18-7-8-23(14)17)21-13-5-3-4-6-15(13)24-2;1-22-8-10(6-18-22)11-7-17-13-12(16-4-5-23(11)13)19-15-21-20-14(24-15)9-2-3-9;1-3-23-14-20-19-13(24-14)18-11-12-16-7-10(22(12)5-4-15-11)9-6-17-21(2)8-9/h2-13H,1H3,(H,20,24);2-12H,1H3,(H,20,24);2-10H,1H3,(H,18,21,22);3-11H,1-2H3,(H,18,21);4-9H,2-3H2,1H3,(H,16,19,21);4-8H,3H2,1-2H3,(H,15,18,19).

What are the key properties of 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine?

5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 2078.39 g/mol, XLogP of 17.32, 24 rotatable bonds, 6 hydrogen bond donors, and 51 hydrogen bond acceptors.

Where does this data come from?

All data for 5-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;5-ethylsulfanyl-N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3,4-thiadiazol-2-amine;N-(2-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,3-benzothiazol-2-amine;3-(1-methylpyrazol-4-yl)-N-(2-phenylpyrazol-3-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(1,2,4-triazol-1-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 161019851), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).