3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide

C117H144N26O10 — CID 161095823

About 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide

3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide (PubChem CID 161095823) has the molecular formula C117H144N26O10 and a molecular weight of 2074.61 g/mol. Its IUPAC name is 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide.

Molecular Properties

• Compound Name: 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide
• PubChem CID: 161095823
• Molecular Formula: C117H144N26O10
• Molecular Weight: 2074.61 g/mol
• Exact Mass: 2073.16
• IUPAC Name: 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide
• SMILES: CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2CC1COC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C3CC3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCNC(=O)C3)nc1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2
• InChI: InChI=1S/C27H34N4O3.C24H31N7O2.C23H29N5O.C22H26N4O2.C21H24N6O2/c1-29(2)27(21-8-4-3-5-9-21)14-12-26(13-15-27)19-30(23-11-7-6-10-22(23)24(28)32)25(33)31(26)16-20-17-34-18-20;1-29(2)24(18-6-4-3-5-7-18)10-8-23(9-11-24)17-31(22(33)28-23)19-14-26-21(27-15-19)30-13-12-25-20(32)16-30;1-27(2)23(18-6-4-3-5-7-18)12-10-22(11-13-23)16-28(21(29)26-22)19-14-24-20(25-15-19)17-8-9-17;1-24-22(16-7-3-2-4-8-16)13-11-21(12-14-22)15-26(20(28)25-21)18-10-6-5-9-17(18)19(23)27;1-23-21(15-6-4-3-5-7-15)10-8-20(9-11-21)14-27(19(28)26-20)16-13-24-17(12-22)25-18(16)29-2/h3-11,20H,12-19H2,1-2H3,(H2,28,32);3-7,14-15H,8-13,16-17H2,1-2H3,(H,25,32)(H,28,33);3-7,14-15,17H,8-13,16H2,1-2H3,(H,26,29);2-10,24H,11-15H2,1H3,(H2,23,27)(H,25,28);3-7,13,23H,8-11,14H2,1-2H3,(H,26,28)
• InChIKey: UHTWTJHGNKYUHI-UHFFFAOYSA-N
• XLogP: 13.87
• TPSA: 424.80 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 23
• Rotatable Bonds: 22
• Heavy Atoms: 153
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2074.61
LogP ≤ 5	13.87
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	23

Frequently Asked Questions

What is the IUPAC name of 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?

The IUPAC name of 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide (CID 161095823) is 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide.

What is the SMILES notation for 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?

The canonical SMILES for 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide is CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2CC1COC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C3CC3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCNC(=O)C3)nc1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2.

What is the InChIKey of 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?

The InChIKey is UHTWTJHGNKYUHI-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H34N4O3.C24H31N7O2.C23H29N5O.C22H26N4O2.C21H24N6O2/c1-29(2)27(21-8-4-3-5-9-21)14-12-26(13-15-27)19-30(23-11-7-6-10-22(23)24(28)32)25(33)31(26)16-20-17-34-18-20;1-29(2)24(18-6-4-3-5-7-18)10-8-23(9-11-24)17-31(22(33)28-23)19-14-26-21(27-15-19)30-13-12-25-20(32)16-30;1-27(2)23(18-6-4-3-5-7-18)12-10-22(11-13-23)16-28(21(29)26-22)19-14-24-20(25-15-19)17-8-9-17;1-24-22(16-7-3-2-4-8-16)13-11-21(12-14-22)15-26(20(28)25-21)18-10-6-5-9-17(18)19(23)27;1-23-21(15-6-4-3-5-7-15)10-8-20(9-11-21)14-27(19(28)26-20)16-13-24-17(12-22)25-18(16)29-2/h3-11,20H,12-19H2,1-2H3,(H2,28,32);3-7,14-15H,8-13,16-17H2,1-2H3,(H,25,32)(H,28,33);3-7,14-15,17H,8-13,16H2,1-2H3,(H,26,29);2-10,24H,11-15H2,1H3,(H2,23,27)(H,25,28);3-7,13,23H,8-11,14H2,1-2H3,(H,26,28).

What are the key properties of 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?

3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide has a molecular weight of 2074.61 g/mol, XLogP of 13.87, 22 rotatable bonds, 9 hydrogen bond donors, and 23 hydrogen bond acceptors.

Where does this data come from?

All data for 3-(2-cyclopropylpyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide is sourced from PubChem (CID 161095823), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).