N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide

C68H50Cl2F6N20O5 — CID 161099102

About N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide

N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide (PubChem CID 161099102) has the molecular formula C68H50Cl2F6N20O5 and a molecular weight of 1412.18 g/mol. Its IUPAC name is N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
• PubChem CID: 161099102
• Molecular Formula: C68H50Cl2F6N20O5
• Molecular Weight: 1412.18 g/mol
• Exact Mass: 1410.36
• IUPAC Name: N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
• SMILES: O=C(Nc1cc(-c2ccccc2)nc2c(C3CCCC3)cnn12)c1cccnc1.O=C(Nc1cc(-c2ccco2)nc2c(C(F)(F)F)cnn12)c1cccnc1.O=C(Nc1cc(Cl)nc2c(C(F)(F)F)cnn12)c1cccnc1.O=C(Nc1cc(Cl)nc2c(C3CC3)cnn12)c1cccnc1
• InChI: InChI=1S/C23H21N5O.C17H10F3N5O2.C15H12ClN5O.C13H7ClF3N5O/c29-23(18-11-6-12-24-14-18)27-21-13-20(17-9-2-1-3-10-17)26-22-19(15-25-28(21)22)16-7-4-5-8-16;18-17(19,20)11-9-22-25-14(24-16(26)10-3-1-5-21-8-10)7-12(23-15(11)25)13-4-2-6-27-13;16-12-6-13(20-15(22)10-2-1-5-17-7-10)21-14(19-12)11(8-18-21)9-3-4-9;14-9-4-10(21-12(23)7-2-1-3-18-5-7)22-11(20-9)8(6-19-22)13(15,16)17/h1-3,6,9-16H,4-5,7-8H2,(H,27,29);1-9H,(H,24,26);1-2,5-9H,3-4H2,(H,20,22);1-6H,(H,21,23)
• InChIKey: UIEPOVHNIZSIJY-UHFFFAOYSA-N
• XLogP: 14.31
• TPSA: 301.86 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 21
• Rotatable Bonds: 12
• Heavy Atoms: 101
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1412.18
LogP ≤ 5	14.31
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	21

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

The IUPAC name of N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide (CID 161099102) is N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide.

What is the SMILES notation for N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

The canonical SMILES for N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide is O=C(Nc1cc(-c2ccccc2)nc2c(C3CCCC3)cnn12)c1cccnc1.O=C(Nc1cc(-c2ccco2)nc2c(C(F)(F)F)cnn12)c1cccnc1.O=C(Nc1cc(Cl)nc2c(C(F)(F)F)cnn12)c1cccnc1.O=C(Nc1cc(Cl)nc2c(C3CC3)cnn12)c1cccnc1.

What is the InChIKey of N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

The InChIKey is UIEPOVHNIZSIJY-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H21N5O.C17H10F3N5O2.C15H12ClN5O.C13H7ClF3N5O/c29-23(18-11-6-12-24-14-18)27-21-13-20(17-9-2-1-3-10-17)26-22-19(15-25-28(21)22)16-7-4-5-8-16;18-17(19,20)11-9-22-25-14(24-16(26)10-3-1-5-21-8-10)7-12(23-15(11)25)13-4-2-6-27-13;16-12-6-13(20-15(22)10-2-1-5-17-7-10)21-14(19-12)11(8-18-21)9-3-4-9;14-9-4-10(21-12(23)7-2-1-3-18-5-7)22-11(20-9)8(6-19-22)13(15,16)17/h1-3,6,9-16H,4-5,7-8H2,(H,27,29);1-9H,(H,24,26);1-2,5-9H,3-4H2,(H,20,22);1-6H,(H,21,23).

What are the key properties of N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide has a molecular weight of 1412.18 g/mol, XLogP of 14.31, 12 rotatable bonds, 4 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide is sourced from PubChem (CID 161099102), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).