(2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide

C132H122N30O10 — CID 161107289

IUPAC(2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide
SMILESCOCc1ccccc1-c1cc2cc(NC(=O)C3C[C@H]3C#N)ncc2c(N)n1.COCc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.[C-]#[N+][C@@H]1CC[C@H]2C(C(=O)Nc3cc4cc(-c5ccccc5C)nc(N)c4cn3)[C@@H]12.[C-]#[N+][C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3ccccc3CCOC)nc(N)c2cn1.[C-]#[N+][C@H]1CC[C@H]2C(C(=O)Nc3cc4cc(-c5ccccc5C)nc(N)c4cn3)[C@@H]12.[C-]#[N+][C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3ccccc3CCOC)nc(N)c2cn1
InChIInChI=1S/2C23H21N5O.2C22H21N5O2.2C21H19N5O2/c2*1-12-5-3-4-6-14(12)18-9-13-10-19(26-11-16(13)22(24)27-18)28-23(29)21-15-7-8-17(25-2)20(15)21;2*1-24-18-11-16(18)22(28)27-20-10-14-9-19(26-21(23)17(14)12-25-20)15-6-4-3-5-13(15)7-8-29-2;2*1-28-11-12-4-2-3-5-15(12)18-7-13-8-19(24-10-17(13)20(23)25-18)26-21(27)16-6-14(16)9-22/h2*3-6,9-11,15,17,20-21H,7-8H2,1H3,(H2,24,27)(H,26,28,29);2*3-6,9-10,12,16,18H,7-8,11H2,2H3,(H2,23,26)(H,25,27,28);2*2-5,7-8,10,14,16H,6,11H2,1H3,(H2,23,25)(H,24,26,27)/t15-,17+,20-,21?;15-,17-,20-,21?;2*16-,18-;14-,16?;14-,16+/m111001/s1
InChIKeyUJFMIGDVJWJUOH-CLIIAVFWSA-N
MW2288.63 g/mol
LogP21.02
Rot. Bonds28

About (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide

(2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide (PubChem CID 161107289) has the molecular formula C132H122N30O10 and a molecular weight of 2288.63 g/mol. Its IUPAC name is (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide.

Molecular Properties

Compound Name(2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide
PubChem CID161107289
Molecular FormulaC132H122N30O10
Molecular Weight2288.63 g/mol
Exact Mass2287.00
IUPAC Name(2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide
SMILESCOCc1ccccc1-c1cc2cc(NC(=O)C3C[C@H]3C#N)ncc2c(N)n1.COCc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.[C-]#[N+][C@@H]1CC[C@H]2C(C(=O)Nc3cc4cc(-c5ccccc5C)nc(N)c4cn3)[C@@H]12.[C-]#[N+][C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3ccccc3CCOC)nc(N)c2cn1.[C-]#[N+][C@H]1CC[C@H]2C(C(=O)Nc3cc4cc(-c5ccccc5C)nc(N)c4cn3)[C@@H]12.[C-]#[N+][C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3ccccc3CCOC)nc(N)c2cn1
InChIInChI=1S/2C23H21N5O.2C22H21N5O2.2C21H19N5O2/c2*1-12-5-3-4-6-14(12)18-9-13-10-19(26-11-16(13)22(24)27-18)28-23(29)21-15-7-8-17(25-2)20(15)21;2*1-24-18-11-16(18)22(28)27-20-10-14-9-19(26-21(23)17(14)12-25-20)15-6-4-3-5-13(15)7-8-29-2;2*1-28-11-12-4-2-3-5-15(12)18-7-13-8-19(24-10-17(13)20(23)25-18)26-21(27)16-6-14(16)9-22/h2*3-6,9-11,15,17,20-21H,7-8H2,1H3,(H2,24,27)(H,26,28,29);2*3-6,9-10,12,16,18H,7-8,11H2,2H3,(H2,23,26)(H,25,27,28);2*2-5,7-8,10,14,16H,6,11H2,1H3,(H2,23,25)(H,24,26,27)/t15-,17+,20-,21?;15-,17-,20-,21?;2*16-,18-;14-,16?;14-,16+/m111001/s1
InChIKeyUJFMIGDVJWJUOH-CLIIAVFWSA-N
XLogP21.02
TPSA587.34 Ų
H-Bond Donors12
H-Bond Acceptors30
Rotatable Bonds28
Heavy Atoms172
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002288.63
LogP ≤ 521.02
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1030

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}

Analyze (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[8-amino-6-(2-ethylphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 158576696
cis-(1R,2R)-N-[8-amino-6-[2-(2-hydroxy-2-methylpropyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 157087111
cis-(1S,2S)-N-[8-amino-6-(2-cyanophenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 139469002
(1R,2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)-3-methylcyclopropane-1-carboxamide
CID 158074691
cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(oxan-4-yl)cyclopropane-1-carboxamide
CID 158215119
cis-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]isoquinolin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 158323167
(1R,5S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-morpholin-4-ylbicyclo[3.1.0]hexane-6-carboxamide
CID 158533102
N-[8-amino-6-(4-propan-2-yl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 135344416
(1S)-N-[8-amino-6-(3-hydroxy-6-methyl-2-oxo-1,3-dihydroindol-5-yl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 139468593
(2S)-N-[8-amino-6-(5-propan-2-yl-1H-pyrazol-4-yl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 139468746
trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 158709120
trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(2-oxo-1,3-oxazolidin-5-yl)cyclopropane-1-carboxamide
CID 160702404

Frequently Asked Questions

What is the IUPAC name of (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide?
The IUPAC name of (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide (CID 161107289) is (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide.
What is the SMILES notation for (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide?
The canonical SMILES for (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide is COCc1ccccc1-c1cc2cc(NC(=O)C3C[C@H]3C#N)ncc2c(N)n1.COCc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.[C-]#[N+][C@@H]1CC[C@H]2C(C(=O)Nc3cc4cc(-c5ccccc5C)nc(N)c4cn3)[C@@H]12.[C-]#[N+][C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3ccccc3CCOC)nc(N)c2cn1.[C-]#[N+][C@H]1CC[C@H]2C(C(=O)Nc3cc4cc(-c5ccccc5C)nc(N)c4cn3)[C@@H]12.[C-]#[N+][C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3ccccc3CCOC)nc(N)c2cn1.
What is the InChIKey of (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide?
The InChIKey is UJFMIGDVJWJUOH-CLIIAVFWSA-N. The full InChI is InChI=1S/2C23H21N5O.2C22H21N5O2.2C21H19N5O2/c2*1-12-5-3-4-6-14(12)18-9-13-10-19(26-11-16(13)22(24)27-18)28-23(29)21-15-7-8-17(25-2)20(15)21;2*1-24-18-11-16(18)22(28)27-20-10-14-9-19(26-21(23)17(14)12-25-20)15-6-4-3-5-13(15)7-8-29-2;2*1-28-11-12-4-2-3-5-15(12)18-7-13-8-19(24-10-17(13)20(23)25-18)26-21(27)16-6-14(16)9-22/h2*3-6,9-11,15,17,20-21H,7-8H2,1H3,(H2,24,27)(H,26,28,29);2*3-6,9-10,12,16,18H,7-8,11H2,2H3,(H2,23,26)(H,25,27,28);2*2-5,7-8,10,14,16H,6,11H2,1H3,(H2,23,25)(H,24,26,27)/t15-,17+,20-,21?;15-,17-,20-,21?;2*16-,18-;14-,16?;14-,16+/m111001/s1.
What are the key properties of (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide?
(2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide has a molecular weight of 2288.63 g/mol, XLogP of 21.02, 28 rotatable bonds, 12 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;(1S,2S,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;(1S,2R,5R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-isocyanobicyclo[3.1.0]hexane-6-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(methoxymethyl)phenyl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-methoxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-isocyanocyclopropane-1-carboxamide is sourced from PubChem (CID 161107289), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).