N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide

C144H145F6N29O10 — CID 161119261

About N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide

N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 161119261) has the molecular formula C144H145F6N29O10 and a molecular weight of 2555.92 g/mol. Its IUPAC name is N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

• Compound Name: N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide
• PubChem CID: 161119261
• Molecular Formula: C144H145F6N29O10
• Molecular Weight: 2555.92 g/mol
• Exact Mass: 2554.16
• IUPAC Name: N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide
• SMILES: CCC(NC(=O)c1ncn2c(C)cc(-c3ccccn3)nc12)c1ccc(C)cc1.CCc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COCc1cc(-c2ccc(F)cc2)n2cnc(C(=O)N[C@@H](C)C3CC3)c2n1.COCc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1ccccc1[C@H](C)NC(=O)c1ncn2c(C)cc(-c3ccc(F)cc3)nc12.Cc1cn2cnc(C(=O)N[C@@H](C)C3CC3)c2nc1-c1ccc(F)cc1
• InChI: InChI=1S/C23H21FN4O.C23H23N5O.2C20H21FN4O2.C20H21FN4O.C19H19FN4O2.C19H19FN4O/c1-14-6-4-5-7-19(14)16(3)26-23(29)21-22-27-20(12-15(2)28(22)13-25-21)17-8-10-18(24)11-9-17;1-4-18(17-10-8-15(2)9-11-17)27-23(29)21-22-26-20(19-7-5-6-12-24-19)13-16(3)28(22)14-25-21;1-12(13-3-4-13)23-20(26)18-19-24-17(14-5-7-15(21)8-6-14)9-16(10-27-2)25(19)11-22-18;1-12(13-3-4-13)23-20(26)18-19-24-16(10-27-2)9-17(25(19)11-22-18)14-5-7-15(21)8-6-14;1-3-16-10-17(14-6-8-15(21)9-7-14)24-19-18(22-11-25(16)19)20(26)23-12(2)13-4-5-13;1-11(12-3-4-12)22-19(25)17-18-23-15(13-5-7-14(20)8-6-13)9-16(26-2)24(18)10-21-17;1-11-9-24-10-21-17(19(25)22-12(2)13-3-4-13)18(24)23-16(11)14-5-7-15(20)8-6-14/h4-13,16H,1-3H3,(H,26,29);5-14,18H,4H2,1-3H3,(H,27,29);2*5-9,11-13H,3-4,10H2,1-2H3,(H,23,26);6-13H,3-5H2,1-2H3,(H,23,26);5-12H,3-4H2,1-2H3,(H,22,25);5-10,12-13H,3-4H2,1-2H3,(H,22,25)/t16-;;3*12-;11-;12-/m0.00000/s1
• InChIKey: UKSRFHFVBBYXOR-QSPLOLCKSA-N
• XLogP: 25.42
• TPSA: 455.61 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 32
• Rotatable Bonds: 35
• Heavy Atoms: 189
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2555.92
LogP ≤ 5	25.42
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

The IUPAC name of N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide (CID 161119261) is N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide.

What is the SMILES notation for N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

The canonical SMILES for N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide is CCC(NC(=O)c1ncn2c(C)cc(-c3ccccn3)nc12)c1ccc(C)cc1.CCc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COCc1cc(-c2ccc(F)cc2)n2cnc(C(=O)N[C@@H](C)C3CC3)c2n1.COCc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1ccccc1[C@H](C)NC(=O)c1ncn2c(C)cc(-c3ccc(F)cc3)nc12.Cc1cn2cnc(C(=O)N[C@@H](C)C3CC3)c2nc1-c1ccc(F)cc1.

What is the InChIKey of N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

The InChIKey is UKSRFHFVBBYXOR-QSPLOLCKSA-N. The full InChI is InChI=1S/C23H21FN4O.C23H23N5O.2C20H21FN4O2.C20H21FN4O.C19H19FN4O2.C19H19FN4O/c1-14-6-4-5-7-19(14)16(3)26-23(29)21-22-27-20(12-15(2)28(22)13-25-21)17-8-10-18(24)11-9-17;1-4-18(17-10-8-15(2)9-11-17)27-23(29)21-22-26-20(19-7-5-6-12-24-19)13-16(3)28(22)14-25-21;1-12(13-3-4-13)23-20(26)18-19-24-17(14-5-7-15(21)8-6-14)9-16(10-27-2)25(19)11-22-18;1-12(13-3-4-13)23-20(26)18-19-24-16(10-27-2)9-17(25(19)11-22-18)14-5-7-15(21)8-6-14;1-3-16-10-17(14-6-8-15(21)9-7-14)24-19-18(22-11-25(16)19)20(26)23-12(2)13-4-5-13;1-11(12-3-4-12)22-19(25)17-18-23-15(13-5-7-14(20)8-6-13)9-16(26-2)24(18)10-21-17;1-11-9-24-10-21-17(19(25)22-12(2)13-3-4-13)18(24)23-16(11)14-5-7-15(20)8-6-14/h4-13,16H,1-3H3,(H,26,29);5-14,18H,4H2,1-3H3,(H,27,29);2*5-9,11-13H,3-4,10H2,1-2H3,(H,23,26);6-13H,3-5H2,1-2H3,(H,23,26);5-12H,3-4H2,1-2H3,(H,22,25);5-10,12-13H,3-4H2,1-2H3,(H,22,25)/t16-;;3*12-;11-;12-/m0.00000/s1.

What are the key properties of N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2555.92 g/mol, XLogP of 25.42, 35 rotatable bonds, 7 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(4-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-methoxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-(4-fluorophenyl)-2-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(1S)-1-(2-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-methylphenyl)propyl]-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 161119261), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).