N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide

C114H123F11N26O7 — CID 161129871

IUPACN-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCCc1cc(-c2cccc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COCc1cc(-c2cc(F)cc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cc(F)cc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cc(F)ccc2F)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(N2CCCC(F)(F)C2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12
InChIInChI=1S/C20H20F2N4O2.C20H21FN4O.2C19H18F2N4O.2C18H23F2N5O/c1-11(12-3-4-12)24-20(27)18-19-25-17(13-5-14(21)7-15(22)6-13)8-16(9-28-2)26(19)10-23-18;1-3-16-10-17(14-5-4-6-15(21)9-14)24-19-18(22-11-25(16)19)20(26)23-12(2)13-7-8-13;1-10-5-16(13-6-14(20)8-15(21)7-13)24-18-17(22-9-25(10)18)19(26)23-11(2)12-3-4-12;1-10-7-16(14-8-13(20)5-6-15(14)21)24-18-17(22-9-25(10)18)19(26)23-11(2)12-3-4-12;1-11-8-14(24-7-3-6-18(19,20)9-24)23-16-15(21-10-25(11)16)17(26)22-12(2)13-4-5-13;1-11-9-14(24-7-5-18(19,20)6-8-24)23-16-15(21-10-25(11)16)17(26)22-12(2)13-3-4-13/h5-8,10-12H,3-4,9H2,1-2H3,(H,24,27);4-6,9-13H,3,7-8H2,1-2H3,(H,23,26);2*5-9,11-12H,3-4H2,1-2H3,(H,23,26);8,10,12-13H,3-7,9H2,1-2H3,(H,22,26);9-10,12-13H,3-8H2,1-2H3,(H,22,26)/t11-;12-;2*11-;2*12-/m000000/s1
InChIKeyUMARQXAJKXNMSY-HGKTZRMVSA-N
MW2178.39 g/mol
LogP19.60
Rot. Bonds27

About N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide

N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 161129871) has the molecular formula C114H123F11N26O7 and a molecular weight of 2178.39 g/mol. Its IUPAC name is N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound NameN-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide
PubChem CID161129871
Molecular FormulaC114H123F11N26O7
Molecular Weight2178.39 g/mol
Exact Mass2176.99
IUPAC NameN-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCCc1cc(-c2cccc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COCc1cc(-c2cc(F)cc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cc(F)cc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cc(F)ccc2F)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(N2CCCC(F)(F)C2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12
InChIInChI=1S/C20H20F2N4O2.C20H21FN4O.2C19H18F2N4O.2C18H23F2N5O/c1-11(12-3-4-12)24-20(27)18-19-25-17(13-5-14(21)7-15(22)6-13)8-16(9-28-2)26(19)10-23-18;1-3-16-10-17(14-5-4-6-15(21)9-14)24-19-18(22-11-25(16)19)20(26)23-12(2)13-7-8-13;1-10-5-16(13-6-14(20)8-15(21)7-13)24-18-17(22-9-25(10)18)19(26)23-11(2)12-3-4-12;1-10-7-16(14-8-13(20)5-6-15(14)21)24-18-17(22-9-25(10)18)19(26)23-11(2)12-3-4-12;1-11-8-14(24-7-3-6-18(19,20)9-24)23-16-15(21-10-25(11)16)17(26)22-12(2)13-4-5-13;1-11-9-14(24-7-5-18(19,20)6-8-24)23-16-15(21-10-25(11)16)17(26)22-12(2)13-3-4-13/h5-8,10-12H,3-4,9H2,1-2H3,(H,24,27);4-6,9-13H,3,7-8H2,1-2H3,(H,23,26);2*5-9,11-12H,3-4H2,1-2H3,(H,23,26);8,10,12-13H,3-7,9H2,1-2H3,(H,22,26);9-10,12-13H,3-8H2,1-2H3,(H,22,26)/t11-;12-;2*11-;2*12-/m000000/s1
InChIKeyUMARQXAJKXNMSY-HGKTZRMVSA-N
XLogP19.60
TPSA371.45 Ų
H-Bond Donors6
H-Bond Acceptors27
Rotatable Bonds27
Heavy Atoms158
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002178.39
LogP ≤ 519.60
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1027

Analyze N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide with MolForge

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Related Compounds

N-tert-butyl-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3-fluorophenoxy)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-2-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-3-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-pyridin-4-yloxyimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 157103535
7-[2-(3-cyclopropylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;7-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;1-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]imidazo[1,2-a]pyridin-3-yl]ethanol;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(oxan-4-yl)imidazo[1,2-a]pyridine-3-carboxamide;7-[2-(3-methylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;7-[2-[3-(trifluoromethyl)phenyl]-3-pyridinyl]imidazo[1,5-a]pyridine
CID 157129590
bis(N-[(1S,5R)-3-butoxy-8-bicyclo[3.2.1]octanyl]-2-(methoxymethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide);N-[(1S,5R)-3-butoxy-8-bicyclo[3.2.1]octanyl]-4-(methoxymethyl)-2-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1R)-1-cyclopropylethyl]-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-(trifluoromethoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;bis(2,4-dimethyl-N-[(1S,5R)-3-[(2-methylpropan-2-yl)oxy]-8-bicyclo[3.2.1]octanyl]imidazo[1,5-a]pyrimidine-8-carboxamide);2-isocyano-4-methyl-N-[2,2,2-trifluoro-1-(4-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 157486193
(7R)-7-[(2S)-butan-2-yl]-1-[(3,4-difluorophenyl)methyl]-5-ethyl-2-[6-(trifluoromethyl)-3-pyridinyl]-7,8-dihydroimidazo[2,1-b]purin-4-one;(7R)-7-cyclopropyl-2-[6-(1,1-difluoroethyl)-3-pyridinyl]-1-[(3,4-difluorophenyl)methyl]-5-ethyl-7,8-dihydroimidazo[2,1-b]purin-4-one;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-1-[(3,4-difluorophenyl)methyl]-5-ethylspiro[8H-imidazo[2,1-b]purine-7,1'-cyclohexane]-4-one;(7R)-1-[(2,4-difluorophenyl)methyl]-5-ethyl-2-(4-methylphenyl)-7-propan-2-yl-7,8-dihydroimidazo[2,1-b]purin-4-one;(7R)-1-[(3,4-difluorophenyl)methyl]-5-(2-methoxyethyl)-2-(4-phenylphenyl)-7-propan-2-yl-7,8-dihydroimidazo[2,1-b]purin-4-one;methane
CID 157697202
4-[6-(aminomethyl)-2-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-3-yl]-N-[(1S)-1-phenylethyl]pyrimidin-2-amine;4-[6-(azidomethyl)-2-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-3-yl]-N-[(1S)-1-phenylethyl]pyrimidin-2-amine;benzyl N-[3-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]-2-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]carbamate;N-[2-(dimethylamino)ethyl]-3-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]-2-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridine-6-carboxamide
CID 158033548
4-[(5-Fluoro-2-pyridinyl)methoxy]-1-(6,7,8,9-tetrahydropyrido[1,2-a]benzimidazol-3-yl)pyridin-2-one;methane;4-phenylmethoxy-1-(4-propan-2-yl-1,4,8-triazatricyclo[7.4.0.02,7]trideca-2(7),8,10,12-tetraen-11-yl)pyridin-2-one;4-phenylmethoxy-1-(6,7,8,9-tetrahydropyrido[1,2-a]benzimidazol-3-yl)pyridin-2-one;1-(6,7,8,9-tetrahydropyrido[1,2-a]benzimidazol-3-yl)-4-[4-(trifluoromethyl)phenyl]pyridin-2-one;1-(6,7,8,9-tetrahydropyrido[1,2-a]benzimidazol-3-yl)-4-[[6-(trifluoromethyl)-3-pyridinyl]methoxy]pyridin-2-one;1-(6,7,8,9-tetrahydropyrido[1,2-a]benzimidazol-3-yl)-4-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-one
CID 158209445
4-[(5-Fluoro-2-pyridinyl)methoxy]-1-(1,4,8-triazatricyclo[7.4.0.02,7]trideca-2(7),8,10,12-tetraen-11-yl)pyridin-2-one;4-phenylmethoxy-1-(1,4,8-triazatricyclo[7.4.0.02,7]trideca-2(7),8,10,12-tetraen-11-yl)pyridin-2-one;1-(1,4,8-triazatricyclo[7.4.0.02,7]trideca-2(7),8,10,12-tetraen-11-yl)-4-[4-(trifluoromethyl)phenyl]pyridin-2-one;1-(1,4,8-triazatricyclo[7.4.0.02,7]trideca-2(7),8,10,12-tetraen-11-yl)-4-[[6-(trifluoromethyl)-3-pyridinyl]methoxy]pyridin-2-one;1-(1,4,8-triazatricyclo[7.4.0.02,7]trideca-2(7),8,10,12-tetraen-11-yl)-4-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-one
CID 158248927
2-(methoxymethyl)-4-methyl-N-[2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-(methoxymethyl)-2-methyl-N-[2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158380934
2-(2-cyano-3-methoxyphenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyano-2-methoxyphenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-cyano-3-methoxyphenyl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyano-2-methoxyphenyl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyano-2-methoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluoro-2-methoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158461084
N-(1-cyclopropylethyl)-2-(2-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-2-(2-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-pyridin-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-(2-fluorophenyl)ethyl]-4-methyl-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-2-yl-N-[2,2,2-trifluoro-1-(4-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[2,2,2-trifluoro-1-(4-methylphenyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158604275
N-(1-cyclohexylethyl)-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[1-(3-ethynylphenyl)cyclopropyl]-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-(3-ethynylphenyl)-2,2,2-trifluoroethyl]-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1R)-1-(3-ethynylphenyl)-2,2,2-trifluoroethyl]-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[1-(3-ethynylphenyl)-2,2,2-trifluoroethyl]-2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 158671965
7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-N-(4-fluorophenyl)-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-N-pyridin-2-yl-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;benzyl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxylate;tert-butyl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxylate;1-ethoxycarbonyloxyethyl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxylate;propan-2-yl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxylate
CID 159066386

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide?
The IUPAC name of N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide (CID 161129871) is N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide.
What is the SMILES notation for N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide?
The canonical SMILES for N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide is CCc1cc(-c2cccc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.COCc1cc(-c2cc(F)cc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cc(F)cc(F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cc(F)ccc2F)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(N2CCCC(F)(F)C2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.
What is the InChIKey of N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide?
The InChIKey is UMARQXAJKXNMSY-HGKTZRMVSA-N. The full InChI is InChI=1S/C20H20F2N4O2.C20H21FN4O.2C19H18F2N4O.2C18H23F2N5O/c1-11(12-3-4-12)24-20(27)18-19-25-17(13-5-14(21)7-15(22)6-13)8-16(9-28-2)26(19)10-23-18;1-3-16-10-17(14-5-4-6-15(21)9-14)24-19-18(22-11-25(16)19)20(26)23-12(2)13-7-8-13;1-10-5-16(13-6-14(20)8-15(21)7-13)24-18-17(22-9-25(10)18)19(26)23-11(2)12-3-4-12;1-10-7-16(14-8-13(20)5-6-15(14)21)24-18-17(22-9-25(10)18)19(26)23-11(2)12-3-4-12;1-11-8-14(24-7-3-6-18(19,20)9-24)23-16-15(21-10-25(11)16)17(26)22-12(2)13-4-5-13;1-11-9-14(24-7-5-18(19,20)6-8-24)23-16-15(21-10-25(11)16)17(26)22-12(2)13-3-4-13/h5-8,10-12H,3-4,9H2,1-2H3,(H,24,27);4-6,9-13H,3,7-8H2,1-2H3,(H,23,26);2*5-9,11-12H,3-4H2,1-2H3,(H,23,26);8,10,12-13H,3-7,9H2,1-2H3,(H,22,26);9-10,12-13H,3-8H2,1-2H3,(H,22,26)/t11-;12-;2*11-;2*12-/m000000/s1.
What are the key properties of N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide?
N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2178.39 g/mol, XLogP of 19.60, 27 rotatable bonds, 6 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-(methoxymethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(2,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,5-difluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(3,3-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4,4-difluoropiperidin-1-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-ethyl-2-(3-fluorophenyl)imidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 161129871), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).