4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile

C91H74Cl3F6N33O4 — CID 161162858

IUPAC4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
SMILESCc1nc(N)c(C#N)c(N[C@@H](C)c2nc3cccc(C(F)(F)F)c3c(=O)n2-c2cccnc2)n1.Cc1nc(N)c(C#N)c(N[C@@H](C)c2nc3cccc(Cl)c3c(=O)n2-c2cnc(N)cc2C)n1.Cc1nc(N)c(C#N)c(N[C@H](c2nc3c(F)ccc(Cl)c3c(=O)n2-c2cncc(F)c2C)C2CC2)n1.Cc1nc(N)c(C#N)c(N[C@H](c2nc3ccc(F)c(Cl)c3c(=O)n2-c2cccnc2)C2CC2)n1
InChIInChI=1S/C24H19ClF2N8O.C23H18ClFN8O.C22H20ClN9O.C22H17F3N8O/c1-10-16(27)8-30-9-17(10)35-23(34-20-15(26)6-5-14(25)18(20)24(35)36)19(12-3-4-12)33-22-13(7-28)21(29)31-11(2)32-22;1-11-29-20(27)14(9-26)21(30-11)32-19(12-4-5-12)22-31-16-7-6-15(25)18(24)17(16)23(34)33(22)13-3-2-8-28-10-13;1-10-7-17(25)27-9-16(10)32-21(31-15-6-4-5-14(23)18(15)22(32)33)11(2)28-20-13(8-24)19(26)29-12(3)30-20;1-11(29-19-14(9-26)18(27)30-12(2)31-19)20-32-16-7-3-6-15(22(23,24)25)17(16)21(34)33(20)13-5-4-8-28-10-13/h5-6,8-9,12,19H,3-4H2,1-2H3,(H3,29,31,32,33);2-3,6-8,10,12,19H,4-5H2,1H3,(H3,27,29,30,32);4-7,9,11H,1-3H3,(H2,25,27)(H3,26,28,29,30);3-8,10-11H,1-2H3,(H3,27,29,30,31)/t2*19-;2*11-/m0000/s1
InChIKeyUQDNJRSVILITRD-ZQPUTARXSA-N
MW1914.17 g/mol
LogP14.40
Rot. Bonds18

About 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile

4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile (PubChem CID 161162858) has the molecular formula C91H74Cl3F6N33O4 and a molecular weight of 1914.17 g/mol. Its IUPAC name is 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile.

Molecular Properties

Compound Name4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
PubChem CID161162858
Molecular FormulaC91H74Cl3F6N33O4
Molecular Weight1914.17 g/mol
Exact Mass1911.56
IUPAC Name4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
SMILESCc1nc(N)c(C#N)c(N[C@@H](C)c2nc3cccc(C(F)(F)F)c3c(=O)n2-c2cccnc2)n1.Cc1nc(N)c(C#N)c(N[C@@H](C)c2nc3cccc(Cl)c3c(=O)n2-c2cnc(N)cc2C)n1.Cc1nc(N)c(C#N)c(N[C@H](c2nc3c(F)ccc(Cl)c3c(=O)n2-c2cncc(F)c2C)C2CC2)n1.Cc1nc(N)c(C#N)c(N[C@H](c2nc3ccc(F)c(Cl)c3c(=O)n2-c2cccnc2)C2CC2)n1
InChIInChI=1S/C24H19ClF2N8O.C23H18ClFN8O.C22H20ClN9O.C22H17F3N8O/c1-10-16(27)8-30-9-17(10)35-23(34-20-15(26)6-5-14(25)18(20)24(35)36)19(12-3-4-12)33-22-13(7-28)21(29)31-11(2)32-22;1-11-29-20(27)14(9-26)21(30-11)32-19(12-4-5-12)22-31-16-7-6-15(25)18(24)17(16)23(34)33(22)13-3-2-8-28-10-13;1-10-7-17(25)27-9-16(10)32-21(31-15-6-4-5-14(23)18(15)22(32)33)11(2)28-20-13(8-24)19(26)29-12(3)30-20;1-11(29-19-14(9-26)18(27)30-12(2)31-19)20-32-16-7-3-6-15(22(23,24)25)17(16)21(34)33(20)13-5-4-8-28-10-13/h5-6,8-9,12,19H,3-4H2,1-2H3,(H3,29,31,32,33);2-3,6-8,10,12,19H,4-5H2,1H3,(H3,27,29,30,32);4-7,9,11H,1-3H3,(H2,25,27)(H3,26,28,29,30);3-8,10-11H,1-2H3,(H3,27,29,30,31)/t2*19-;2*11-/m0000/s1
InChIKeyUQDNJRSVILITRD-ZQPUTARXSA-N
XLogP14.40
TPSA567.62 Ų
H-Bond Donors9
H-Bond Acceptors37
Rotatable Bonds18
Heavy Atoms137
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001914.17
LogP ≤ 514.40
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1037

Analyze 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile with MolForge

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Launch Full Analysis

Related Compounds

Gs-9901
CID 86763204
2,4-Bis(Azanyl)-6-[[(1~{s})-1-[5-Chloranyl-3-(5-Fluoranyl-4-Methyl-Pyridin-3-Yl)-4-Oxidanylidene-Quinazolin-2-Yl]ethyl]amino]pyrimidine-5-Carbonitrile
CID 86762886
2,4-diamino-6-[[(1S)-1-(5-chloro-8-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)propyl]amino]pyrimidine-5-carbonitrile
CID 86762831
2,4-diamino-6-[[(1S)-1-[5-chloro-8-fluoro-3-(5-fluoro-3-pyridinyl)-4-oxoquinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
CID 86762834
2,4-diamino-6-[[(S)-(5-chloro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]pyrimidine-5-carbonitrile
CID 86763196
2,4-diamino-6-[[(1S)-1-(5-chloro-8-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
CID 86763268
2,4-diamino-6-[[(1S)-1-[5-chloro-4-oxo-3-[5-(trifluoromethyl)pyridin-3-yl]quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
CID 86763202
2,4-diamino-6-[[(1S)-1-[5-chloro-3-(5-fluoro-3-pyridinyl)-4-oxoquinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
CID 86763231
2,4-diamino-6-[[(1S)-1-[5-chloro-3-(5-cyclopropyl-3-pyridinyl)-4-oxoquinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
CID 86763264
2,4-diamino-6-[[(1S)-1-[5-chloro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]propyl]amino]pyrimidine-5-carbonitrile
CID 86763020
2,4-diamino-6-[[(1S)-1-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
CID 86763021
2,4-diamino-6-[[(S)-[3-(6-amino-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]pyrimidine-5-carbonitrile
CID 86763076

Frequently Asked Questions

What is the IUPAC name of 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile?
The IUPAC name of 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile (CID 161162858) is 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile.
What is the SMILES notation for 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile?
The canonical SMILES for 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile is Cc1nc(N)c(C#N)c(N[C@@H](C)c2nc3cccc(C(F)(F)F)c3c(=O)n2-c2cccnc2)n1.Cc1nc(N)c(C#N)c(N[C@@H](C)c2nc3cccc(Cl)c3c(=O)n2-c2cnc(N)cc2C)n1.Cc1nc(N)c(C#N)c(N[C@H](c2nc3c(F)ccc(Cl)c3c(=O)n2-c2cncc(F)c2C)C2CC2)n1.Cc1nc(N)c(C#N)c(N[C@H](c2nc3ccc(F)c(Cl)c3c(=O)n2-c2cccnc2)C2CC2)n1.
What is the InChIKey of 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile?
The InChIKey is UQDNJRSVILITRD-ZQPUTARXSA-N. The full InChI is InChI=1S/C24H19ClF2N8O.C23H18ClFN8O.C22H20ClN9O.C22H17F3N8O/c1-10-16(27)8-30-9-17(10)35-23(34-20-15(26)6-5-14(25)18(20)24(35)36)19(12-3-4-12)33-22-13(7-28)21(29)31-11(2)32-22;1-11-29-20(27)14(9-26)21(30-11)32-19(12-4-5-12)22-31-16-7-6-15(25)18(24)17(16)23(34)33(22)13-3-2-8-28-10-13;1-10-7-17(25)27-9-16(10)32-21(31-15-6-4-5-14(23)18(15)22(32)33)11(2)28-20-13(8-24)19(26)29-12(3)30-20;1-11(29-19-14(9-26)18(27)30-12(2)31-19)20-32-16-7-3-6-15(22(23,24)25)17(16)21(34)33(20)13-5-4-8-28-10-13/h5-6,8-9,12,19H,3-4H2,1-2H3,(H3,29,31,32,33);2-3,6-8,10,12,19H,4-5H2,1H3,(H3,27,29,30,32);4-7,9,11H,1-3H3,(H2,25,27)(H3,26,28,29,30);3-8,10-11H,1-2H3,(H3,27,29,30,31)/t2*19-;2*11-/m0000/s1.
What are the key properties of 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile?
4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile has a molecular weight of 1914.17 g/mol, XLogP of 14.40, 18 rotatable bonds, 9 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for 4-amino-6-[[(1S)-1-[3-(6-amino-4-methyl-3-pyridinyl)-5-chloro-4-oxoquinazolin-2-yl]ethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-[5-chloro-8-fluoro-3-(5-fluoro-4-methyl-3-pyridinyl)-4-oxoquinazolin-2-yl]-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-6-[[(S)-(5-chloro-6-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-cyclopropylmethyl]amino]-2-methylpyrimidine-5-carbonitrile;4-amino-2-methyl-6-[[(1S)-1-[4-oxo-3-pyridin-3-yl-5-(trifluoromethyl)quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile is sourced from PubChem (CID 161162858), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).