(11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one

C105H114F3N25O6 — CID 161243636

About (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one

(11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one (PubChem CID 161243636) has the molecular formula C105H114F3N25O6 and a molecular weight of 1879.23 g/mol. Its IUPAC name is (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one.

Molecular Properties

• Compound Name: (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one
• PubChem CID: 161243636
• Molecular Formula: C105H114F3N25O6
• Molecular Weight: 1879.23 g/mol
• Exact Mass: 1877.93
• IUPAC Name: (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one
• SMILES: C=C(C)c1ccc(CCn2nc3c(c2Nc2ccccc2)C(=O)N(C)C2=N[C@@H]4CCC[C@@H]4N23)cc1.CC(=O)c1ccc(CCn2nc(Nc3ccccc3)c3c2N2C(=N[C@@H]4CCC[C@@H]42)N(C)C3=O)cc1.CC(CN(C)C)Cn1nc(Nc2ccccc2)c2c1N1C(=NC3CCCC31)N(C)C2=O.CN1C(=O)c2c(Nc3ccccc3)nn(Cc3ccc(C(=O)C(C)(F)F)c(F)c3)c2N2C1=N[C@@H]1CCC[C@@H]12
• InChI: InChI=1S/C28H30N6O.C27H25F3N6O2.C27H28N6O2.C23H31N7O/c1-18(2)20-14-12-19(13-15-20)16-17-33-25(29-21-8-5-4-6-9-21)24-26(31-33)34-23-11-7-10-22(23)30-28(34)32(3)27(24)35;1-27(29,30)22(37)17-12-11-15(13-18(17)28)14-35-24-21(23(33-35)31-16-7-4-3-5-8-16)25(38)34(2)26-32-19-9-6-10-20(19)36(24)26;1-17(34)19-13-11-18(12-14-19)15-16-32-25-23(24(30-32)28-20-7-4-3-5-8-20)26(35)31(2)27-29-21-9-6-10-22(21)33(25)27;1-15(13-27(2)3)14-29-21-19(20(26-29)24-16-9-6-5-7-10-16)22(31)28(4)23-25-17-11-8-12-18(17)30(21)23/h4-6,8-9,12-15,22-23,29H,1,7,10-11,16-17H2,2-3H3;3-5,7-8,11-13,19-20H,6,9-10,14H2,1-2H3,(H,31,33);3-5,7-8,11-14,21-22H,6,9-10,15-16H2,1-2H3,(H,28,30);5-7,9-10,15,17-18H,8,11-14H2,1-4H3,(H,24,26)/t22-,23+;19-,20+;21-,22+;/m111./s1
• InChIKey: VAIMVEQBOWTYST-PUMDUBPPSA-N
• XLogP: 17.18
• TPSA: 300.42 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 27
• Rotatable Bonds: 24
• Heavy Atoms: 139
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1879.23
LogP ≤ 5	17.18
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one?

The IUPAC name of (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one (CID 161243636) is (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one.

What is the SMILES notation for (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one?

The canonical SMILES for (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one is C=C(C)c1ccc(CCn2nc3c(c2Nc2ccccc2)C(=O)N(C)C2=N[C@@H]4CCC[C@@H]4N23)cc1.CC(=O)c1ccc(CCn2nc(Nc3ccccc3)c3c2N2C(=N[C@@H]4CCC[C@@H]42)N(C)C3=O)cc1.CC(CN(C)C)Cn1nc(Nc2ccccc2)c2c1N1C(=NC3CCCC31)N(C)C2=O.CN1C(=O)c2c(Nc3ccccc3)nn(Cc3ccc(C(=O)C(C)(F)F)c(F)c3)c2N2C1=N[C@@H]1CCC[C@@H]12.

What is the InChIKey of (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one?

The InChIKey is VAIMVEQBOWTYST-PUMDUBPPSA-N. The full InChI is InChI=1S/C28H30N6O.C27H25F3N6O2.C27H28N6O2.C23H31N7O/c1-18(2)20-14-12-19(13-15-20)16-17-33-25(29-21-8-5-4-6-9-21)24-26(31-33)34-23-11-7-10-22(23)30-28(34)32(3)27(24)35;1-27(29,30)22(37)17-12-11-15(13-18(17)28)14-35-24-21(23(33-35)31-16-7-4-3-5-8-16)25(38)34(2)26-32-19-9-6-10-20(19)36(24)26;1-17(34)19-13-11-18(12-14-19)15-16-32-25-23(24(30-32)28-20-7-4-3-5-8-20)26(35)31(2)27-29-21-9-6-10-22(21)33(25)27;1-15(13-27(2)3)14-29-21-19(20(26-29)24-16-9-6-5-7-10-16)22(31)28(4)23-25-17-11-8-12-18(17)30(21)23/h4-6,8-9,12-15,22-23,29H,1,7,10-11,16-17H2,2-3H3;3-5,7-8,11-13,19-20H,6,9-10,14H2,1-2H3,(H,31,33);3-5,7-8,11-14,21-22H,6,9-10,15-16H2,1-2H3,(H,28,30);5-7,9-10,15,17-18H,8,11-14H2,1-4H3,(H,24,26)/t22-,23+;19-,20+;21-,22+;/m111./s1.

What are the key properties of (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one?

(11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one has a molecular weight of 1879.23 g/mol, XLogP of 17.18, 24 rotatable bonds, 4 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for (11R,15S)-3-[2-(4-acetylphenyl)ethyl]-5-anilino-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-3-[[4-(2,2-difluoropropanoyl)-3-fluorophenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;5-anilino-3-[3-(dimethylamino)-2-methylpropyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2(6),4,9-trien-7-one;(11R,15S)-5-anilino-8-methyl-4-[2-(4-prop-1-en-2-ylphenyl)ethyl]-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one is sourced from PubChem (CID 161243636), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).