N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide

C170H185F7N28O11 — CID 161269933

IUPACN-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
SMILESCCCOC1CCC(NC(=O)c2ccn3c(C)cc(-c4cccnc4)nc23)CC1.C[C@H](NC(=O)c1ccn2cc(-c3ccc(F)cc3)cnc12)C1CC1.Cc1c(-c2ccc(F)cc2)cnc2c(C(=O)N[C@@H](C)C3CC3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC3CCC(OC(C)(C)C)CC3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC3CCC(OCC(C)C)CC3)ccn12.Cc1cn2ccc(C(=O)N[C@@H](C)C3CC3)c2nc1-c1ccc(F)cc1.Cc1nc2c(C(=O)N[C@@H](C)C3CC3)ccn2c(C)c1-c1ccc(F)cc1
InChIInChI=1S/2C24H30N4O2.C23H28N4O2.C21H22FN3O.2C20H20FN3O.C19H17F3N4O.C19H18FN3O/c1-16-14-21(17-6-5-12-25-15-17)27-22-20(11-13-28(16)22)23(29)26-18-7-9-19(10-8-18)30-24(2,3)4;1-16(2)15-30-20-8-6-19(7-9-20)26-24(29)21-10-12-28-17(3)13-22(27-23(21)28)18-5-4-11-25-14-18;1-3-13-29-19-8-6-18(7-9-19)25-23(28)20-10-12-27-16(2)14-21(26-22(20)27)17-5-4-11-24-15-17;1-12(15-4-5-15)24-21(26)18-10-11-25-14(3)19(13(2)23-20(18)25)16-6-8-17(22)9-7-16;1-12(14-3-4-14)23-20(25)17-9-10-24-13(2)18(11-22-19(17)24)15-5-7-16(21)8-6-15;1-12-11-24-10-9-17(20(25)22-13(2)14-3-4-14)19(24)23-18(12)15-5-7-16(21)8-6-15;1-11-9-15(13-3-2-7-23-10-13)24-17-14(6-8-26(11)17)18(27)25-16(12-4-5-12)19(20,21)22;1-12(13-2-3-13)22-19(24)17-8-9-23-11-15(10-21-18(17)23)14-4-6-16(20)7-5-14/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,26,29);4-5,10-14,16,19-20H,6-9,15H2,1-3H3,(H,26,29);4-5,10-12,14-15,18-19H,3,6-9,13H2,1-2H3,(H,25,28);6-12,15H,4-5H2,1-3H3,(H,24,26);5-12,14H,3-4H2,1-2H3,(H,23,25);5-11,13-14H,3-4H2,1-2H3,(H,22,25);2-3,6-10,12,16H,4-5H2,1H3,(H,25,27);4-13H,2-3H2,1H3,(H,22,24)/t;;;2*12-;13-;;12-/m...000.0/s1
InChIKeyVDRFVIJKDUNYTL-REWAKNIPSA-N
MW2929.52 g/mol
LogP32.84
Rot. Bonds36

About N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide

N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide (PubChem CID 161269933) has the molecular formula C170H185F7N28O11 and a molecular weight of 2929.52 g/mol. Its IUPAC name is N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound NameN-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
PubChem CID161269933
Molecular FormulaC170H185F7N28O11
Molecular Weight2929.52 g/mol
Exact Mass2927.47
IUPAC NameN-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
SMILESCCCOC1CCC(NC(=O)c2ccn3c(C)cc(-c4cccnc4)nc23)CC1.C[C@H](NC(=O)c1ccn2cc(-c3ccc(F)cc3)cnc12)C1CC1.Cc1c(-c2ccc(F)cc2)cnc2c(C(=O)N[C@@H](C)C3CC3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC3CCC(OC(C)(C)C)CC3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC3CCC(OCC(C)C)CC3)ccn12.Cc1cn2ccc(C(=O)N[C@@H](C)C3CC3)c2nc1-c1ccc(F)cc1.Cc1nc2c(C(=O)N[C@@H](C)C3CC3)ccn2c(C)c1-c1ccc(F)cc1
InChIInChI=1S/2C24H30N4O2.C23H28N4O2.C21H22FN3O.2C20H20FN3O.C19H17F3N4O.C19H18FN3O/c1-16-14-21(17-6-5-12-25-15-17)27-22-20(11-13-28(16)22)23(29)26-18-7-9-19(10-8-18)30-24(2,3)4;1-16(2)15-30-20-8-6-19(7-9-20)26-24(29)21-10-12-28-17(3)13-22(27-23(21)28)18-5-4-11-25-14-18;1-3-13-29-19-8-6-18(7-9-19)25-23(28)20-10-12-27-16(2)14-21(26-22(20)27)17-5-4-11-24-15-17;1-12(15-4-5-15)24-21(26)18-10-11-25-14(3)19(13(2)23-20(18)25)16-6-8-17(22)9-7-16;1-12(14-3-4-14)23-20(25)17-9-10-24-13(2)18(11-22-19(17)24)15-5-7-16(21)8-6-15;1-12-11-24-10-9-17(20(25)22-13(2)14-3-4-14)19(24)23-18(12)15-5-7-16(21)8-6-15;1-11-9-15(13-3-2-7-23-10-13)24-17-14(6-8-26(11)17)18(27)25-16(12-4-5-12)19(20,21)22;1-12(13-2-3-13)22-19(24)17-8-9-23-11-15(10-21-18(17)23)14-4-6-16(20)7-5-14/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,26,29);4-5,10-14,16,19-20H,6-9,15H2,1-3H3,(H,26,29);4-5,10-12,14-15,18-19H,3,6-9,13H2,1-2H3,(H,25,28);6-12,15H,4-5H2,1-3H3,(H,24,26);5-12,14H,3-4H2,1-2H3,(H,23,25);5-11,13-14H,3-4H2,1-2H3,(H,22,25);2-3,6-10,12,16H,4-5H2,1H3,(H,25,27);4-13H,2-3H2,1H3,(H,22,24)/t;;;2*12-;13-;;12-/m...000.0/s1
InChIKeyVDRFVIJKDUNYTL-REWAKNIPSA-N
XLogP32.84
TPSA450.45 Ų
H-Bond Donors8
H-Bond Acceptors31
Rotatable Bonds36
Heavy Atoms216
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002929.52
LogP ≤ 532.84
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1031

Analyze N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide with MolForge

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Related Compounds

7-[2-(3-cyclopropylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;7-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;1-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]imidazo[1,2-a]pyridin-3-yl]ethanol;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(oxan-4-yl)imidazo[1,2-a]pyridine-3-carboxamide;7-[2-(3-methylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;7-[2-[3-(trifluoromethyl)phenyl]-3-pyridinyl]imidazo[1,5-a]pyridine
CID 157129590
1-ethyl-5-fluoro-N-(5-fluoro-3-pyridinyl)indole-3-carboxamide;1-(1-ethyl-5-fluoroindol-3-yl)-2-[6-(trifluoromethyl)-3-pyridinyl]ethanone;1-(1-ethyl-5-fluoroindol-3-yl)-2-[2-(trifluoromethyl)pyrimidin-4-yl]ethanone;1-ethyl-5-fluoro-N-[6-(trifluoromethyl)pyrimidin-4-yl]indole-3-carboxamide;5-fluoro-N-(5-fluoro-3-pyridinyl)-1-propan-2-ylindole-3-carboxamide;5-fluoro-1-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]indole-3-carboxamide
CID 157300408
N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide
CID 157380388
N-(1-cyclobutyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-(4-methylbenzoyl)-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-piperidin-4-yl-N-[2,2,2-trifluoro-1-(4-propan-2-yloxycyclohexyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexanecarbonyl)-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 157576382
N-(2-cyclopropylpropan-2-yl)-2,4-dimethylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2,4-dimethylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;2,4-dimethyl-N-(4-pentoxycyclohexyl)pyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(4-ethynylphenyl)-2,4-dimethylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide
CID 158046851
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-fluoro-6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158445712
N-[(1S)-1-cyclobutylethyl]-2-(dimethylamino)-4-methylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-[(1R)-1-cyclobutylethyl]-2-(dimethylamino)-4-methylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(2-cyclobutylpropan-2-yl)-4-methyl-2-morpholin-4-ylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclobutyl-2,2,2-trifluoroethyl)-2-methyl-4-(methylamino)pyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclobutyl-2,2,2-trifluoroethyl)-4-methyl-2-morpholin-4-ylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-phenylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-pyridin-2-ylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide
CID 158491920
6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158808370
6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158885401
N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
CID 159214073
4-[4-amino-7-[(3R)-1-[(E)-4-[cyclopropyl(methyl)amino]but-2-enoyl]pyrrolidin-3-yl]-6-methylpyrrolo[2,3-d]pyrimidin-5-yl]-N-(4-methyl-2-pyridinyl)benzamide;4-[4-amino-7-[(3R)-1-[(E)-4-[cyclopropyl(methyl)amino]but-2-enoyl]pyrrolidin-3-yl]-6-methylpyrrolo[2,3-d]pyrimidin-5-yl]-N-(4-propyl-2-pyridinyl)benzamide;4-[4-amino-7-[(3R)-1-[(E)-4-[cyclopropyl(methyl)amino]but-2-enoyl]pyrrolidin-3-yl]-6-methylpyrrolo[2,3-d]pyrimidin-5-yl]-N-[4-(trifluoromethyl)-2-pyridinyl]benzamide
CID 159466941
N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
CID 159525307

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
The IUPAC name of N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide (CID 161269933) is N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide.
What is the SMILES notation for N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
The canonical SMILES for N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide is CCCOC1CCC(NC(=O)c2ccn3c(C)cc(-c4cccnc4)nc23)CC1.C[C@H](NC(=O)c1ccn2cc(-c3ccc(F)cc3)cnc12)C1CC1.Cc1c(-c2ccc(F)cc2)cnc2c(C(=O)N[C@@H](C)C3CC3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC3CCC(OC(C)(C)C)CC3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC3CCC(OCC(C)C)CC3)ccn12.Cc1cn2ccc(C(=O)N[C@@H](C)C3CC3)c2nc1-c1ccc(F)cc1.Cc1nc2c(C(=O)N[C@@H](C)C3CC3)ccn2c(C)c1-c1ccc(F)cc1.
What is the InChIKey of N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
The InChIKey is VDRFVIJKDUNYTL-REWAKNIPSA-N. The full InChI is InChI=1S/2C24H30N4O2.C23H28N4O2.C21H22FN3O.2C20H20FN3O.C19H17F3N4O.C19H18FN3O/c1-16-14-21(17-6-5-12-25-15-17)27-22-20(11-13-28(16)22)23(29)26-18-7-9-19(10-8-18)30-24(2,3)4;1-16(2)15-30-20-8-6-19(7-9-20)26-24(29)21-10-12-28-17(3)13-22(27-23(21)28)18-5-4-11-25-14-18;1-3-13-29-19-8-6-18(7-9-19)25-23(28)20-10-12-27-16(2)14-21(26-22(20)27)17-5-4-11-24-15-17;1-12(15-4-5-15)24-21(26)18-10-11-25-14(3)19(13(2)23-20(18)25)16-6-8-17(22)9-7-16;1-12(14-3-4-14)23-20(25)17-9-10-24-13(2)18(11-22-19(17)24)15-5-7-16(21)8-6-15;1-12-11-24-10-9-17(20(25)22-13(2)14-3-4-14)19(24)23-18(12)15-5-7-16(21)8-6-15;1-11-9-15(13-3-2-7-23-10-13)24-17-14(6-8-26(11)17)18(27)25-16(12-4-5-12)19(20,21)22;1-12(13-2-3-13)22-19(24)17-8-9-23-11-15(10-21-18(17)23)14-4-6-16(20)7-5-14/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,26,29);4-5,10-14,16,19-20H,6-9,15H2,1-3H3,(H,26,29);4-5,10-12,14-15,18-19H,3,6-9,13H2,1-2H3,(H,25,28);6-12,15H,4-5H2,1-3H3,(H,24,26);5-12,14H,3-4H2,1-2H3,(H,23,25);5-11,13-14H,3-4H2,1-2H3,(H,22,25);2-3,6-10,12,16H,4-5H2,1H3,(H,25,27);4-13H,2-3H2,1H3,(H,22,24)/t;;;2*12-;13-;;12-/m...000.0/s1.
What are the key properties of N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide has a molecular weight of 2929.52 g/mol, XLogP of 32.84, 36 rotatable bonds, 8 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)-3-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-3-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 161269933), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).