N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide

C161H182F5N31O10 — CID 157380388

IUPACN-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide
SMILESCC(C)(NC(=O)c1ccn2ccc(-c3ccc(F)cc3)nc12)C1CC1.COC1CCC(NC(=O)c2ccn3c(C)cc(-c4ccc(F)cc4)nc23)CC1.C[C@H](NC(=O)c1ccn2ccc(-c3ccc(F)cc3)nc12)C1CC1.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(-c2cncnc2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(-c2ncccn2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(NC2CC3CCC(C2)O3)nc2c(C(=O)NC(C)(C)C3CC3)ccn12
InChIInChI=1S/C22H24FN3O2.C22H30N4O2.C20H26F2N4O.C20H20FN3O.C20H22N4O.C19H18FN3O.2C19H21N5O/c1-14-13-20(15-3-5-16(23)6-4-15)25-21-19(11-12-26(14)21)22(27)24-17-7-9-18(28-2)10-8-17;1-13-10-19(23-15-11-16-6-7-17(12-15)28-16)24-20-18(8-9-26(13)20)21(27)25-22(2,3)14-4-5-14;1-13-12-16(25-10-7-20(21,22)8-11-25)23-17-15(6-9-26(13)17)18(27)24-19(2,3)14-4-5-14;1-20(2,14-5-6-14)23-19(25)16-9-11-24-12-10-17(22-18(16)24)13-3-7-15(21)8-4-13;1-13-11-17(14-5-4-9-21-12-14)22-18-16(8-10-24(13)18)19(25)23-20(2,3)15-6-7-15;1-12(13-2-3-13)21-19(24)16-8-10-23-11-9-17(22-18(16)23)14-4-6-15(20)7-5-14;1-12-11-15(16-20-8-4-9-21-16)22-17-14(7-10-24(12)17)18(25)23-19(2,3)13-5-6-13;1-12-8-16(13-9-20-11-21-10-13)22-17-15(6-7-24(12)17)18(25)23-19(2,3)14-4-5-14/h3-6,11-13,17-18H,7-10H2,1-2H3,(H,24,27);8-10,14-17H,4-7,11-12H2,1-3H3,(H,23,24)(H,25,27);6,9,12,14H,4-5,7-8,10-11H2,1-3H3,(H,24,27);3-4,7-12,14H,5-6H2,1-2H3,(H,23,25);4-5,8-12,15H,6-7H2,1-3H3,(H,23,25);4-13H,2-3H2,1H3,(H,21,24);4,7-11,13H,5-6H2,1-3H3,(H,23,25);6-11,14H,4-5H2,1-3H3,(H,23,25)/t;;;;;12-;;/m.....0../s1
InChIKeyBKUTVMPXDBNBNG-JZEYSDSKSA-N
MW2806.42 g/mol
LogP29.00
Rot. Bonds33

About N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide

N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide (PubChem CID 157380388) has the molecular formula C161H182F5N31O10 and a molecular weight of 2806.42 g/mol. Its IUPAC name is N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound NameN-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide
PubChem CID157380388
Molecular FormulaC161H182F5N31O10
Molecular Weight2806.42 g/mol
Exact Mass2804.46
IUPAC NameN-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide
SMILESCC(C)(NC(=O)c1ccn2ccc(-c3ccc(F)cc3)nc12)C1CC1.COC1CCC(NC(=O)c2ccn3c(C)cc(-c4ccc(F)cc4)nc23)CC1.C[C@H](NC(=O)c1ccn2ccc(-c3ccc(F)cc3)nc12)C1CC1.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(-c2cncnc2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(-c2ncccn2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(NC2CC3CCC(C2)O3)nc2c(C(=O)NC(C)(C)C3CC3)ccn12
InChIInChI=1S/C22H24FN3O2.C22H30N4O2.C20H26F2N4O.C20H20FN3O.C20H22N4O.C19H18FN3O.2C19H21N5O/c1-14-13-20(15-3-5-16(23)6-4-15)25-21-19(11-12-26(14)21)22(27)24-17-7-9-18(28-2)10-8-17;1-13-10-19(23-15-11-16-6-7-17(12-15)28-16)24-20-18(8-9-26(13)20)21(27)25-22(2,3)14-4-5-14;1-13-12-16(25-10-7-20(21,22)8-11-25)23-17-15(6-9-26(13)17)18(27)24-19(2,3)14-4-5-14;1-20(2,14-5-6-14)23-19(25)16-9-11-24-12-10-17(22-18(16)24)13-3-7-15(21)8-4-13;1-13-11-17(14-5-4-9-21-12-14)22-18-16(8-10-24(13)18)19(25)23-20(2,3)15-6-7-15;1-12(13-2-3-13)21-19(24)16-8-10-23-11-9-17(22-18(16)23)14-4-6-15(20)7-5-14;1-12-11-15(16-20-8-4-9-21-16)22-17-14(7-10-24(12)17)18(25)23-19(2,3)13-5-6-13;1-12-8-16(13-9-20-11-21-10-13)22-17-15(6-7-24(12)17)18(25)23-19(2,3)14-4-5-14/h3-6,11-13,17-18H,7-10H2,1-2H3,(H,24,27);8-10,14-17H,4-7,11-12H2,1-3H3,(H,23,24)(H,25,27);6,9,12,14H,4-5,7-8,10-11H2,1-3H3,(H,24,27);3-4,7-12,14H,5-6H2,1-2H3,(H,23,25);4-5,8-12,15H,6-7H2,1-3H3,(H,23,25);4-13H,2-3H2,1H3,(H,21,24);4,7-11,13H,5-6H2,1-3H3,(H,23,25);6-11,14H,4-5H2,1-3H3,(H,23,25)/t;;;;;12-;;/m.....0../s1
InChIKeyBKUTVMPXDBNBNG-JZEYSDSKSA-N
XLogP29.00
TPSA469.38 Ų
H-Bond Donors9
H-Bond Acceptors33
Rotatable Bonds33
Heavy Atoms207
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002806.42
LogP ≤ 529.00
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1033

Analyze N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(1-cyclobutyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-(4-methylbenzoyl)-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-piperidin-4-yl-N-[2,2,2-trifluoro-1-(4-propan-2-yloxycyclohexyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexanecarbonyl)-2-pyridin-3-ylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 157576382
N-(2-cyclopropylpropan-2-yl)-2,4-dimethylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2,4-dimethylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;2,4-dimethyl-N-(4-pentoxycyclohexyl)pyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(4-ethynylphenyl)-2,4-dimethylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide
CID 158046851
1-[3-[8-Amino-1-[4-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]imidazo[1,5-a]pyrazin-3-yl]-2-azabicyclo[3.1.0]hexan-2-yl]but-2-yn-1-one;1-[3-[8-amino-1-[4-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]imidazo[1,5-a]pyrazin-3-yl]-2-azabicyclo[3.1.0]hexan-2-yl]prop-2-en-1-one;1-[1-[8-amino-1-[4-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]imidazo[1,5-a]pyrazin-3-yl]-3-oxa-8-azabicyclo[3.2.1]octan-8-yl]but-2-yn-1-one;1-[1-[8-amino-1-[4-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]imidazo[1,5-a]pyrazin-3-yl]-3-oxa-8-azabicyclo[3.2.1]octan-8-yl]prop-2-en-1-one
CID 158417384
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-fluoro-6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158445712
N-[(1S)-1-cyclobutylethyl]-2-(dimethylamino)-4-methylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-[(1R)-1-cyclobutylethyl]-2-(dimethylamino)-4-methylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(2-cyclobutylpropan-2-yl)-4-methyl-2-morpholin-4-ylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclobutyl-2,2,2-trifluoroethyl)-2-methyl-4-(methylamino)pyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclobutyl-2,2,2-trifluoroethyl)-4-methyl-2-morpholin-4-ylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-phenylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide;N-(1-cyclopropylethyl)-4-methyl-2-pyridin-2-ylpyrrolo[1,2-a][1,3,5]triazine-8-carboxamide
CID 158491920
6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158808370
6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158885401
N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-[(2-methylpropan-2-yl)oxy]cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[4-(2-methylpropoxy)cyclohexyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-(4-propoxycyclohexyl)-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
CID 159214073
4-[4-amino-7-[(3R)-1-[(E)-4-[cyclopropyl(methyl)amino]but-2-enoyl]pyrrolidin-3-yl]-6-methylpyrrolo[2,3-d]pyrimidin-5-yl]-N-(4-methyl-2-pyridinyl)benzamide;4-[4-amino-7-[(3R)-1-[(E)-4-[cyclopropyl(methyl)amino]but-2-enoyl]pyrrolidin-3-yl]-6-methylpyrrolo[2,3-d]pyrimidin-5-yl]-N-(4-propyl-2-pyridinyl)benzamide;4-[4-amino-7-[(3R)-1-[(E)-4-[cyclopropyl(methyl)amino]but-2-enoyl]pyrrolidin-3-yl]-6-methylpyrrolo[2,3-d]pyrimidin-5-yl]-N-[4-(trifluoromethyl)-2-pyridinyl]benzamide
CID 159466941
N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide
CID 159525307
6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-fluoro-6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 159554646
2,4-dimethyl-N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;bis(2,4-dimethyl-N-[4-(piperidin-1-ylmethyl)phenyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide);N-[1-(2,4-dimethylpyrrolo[1,2-a]pyrimidin-8-yl)ethenyl]-4-(trifluoromethyl)aniline
CID 159566712

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
The IUPAC name of N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide (CID 157380388) is N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide.
What is the SMILES notation for N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
The canonical SMILES for N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide is CC(C)(NC(=O)c1ccn2ccc(-c3ccc(F)cc3)nc12)C1CC1.COC1CCC(NC(=O)c2ccn3c(C)cc(-c4ccc(F)cc4)nc23)CC1.C[C@H](NC(=O)c1ccn2ccc(-c3ccc(F)cc3)nc12)C1CC1.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(-c2cncnc2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(-c2ncccn2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(N2CCC(F)(F)CC2)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.Cc1cc(NC2CC3CCC(C2)O3)nc2c(C(=O)NC(C)(C)C3CC3)ccn12.
What is the InChIKey of N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
The InChIKey is BKUTVMPXDBNBNG-JZEYSDSKSA-N. The full InChI is InChI=1S/C22H24FN3O2.C22H30N4O2.C20H26F2N4O.C20H20FN3O.C20H22N4O.C19H18FN3O.2C19H21N5O/c1-14-13-20(15-3-5-16(23)6-4-15)25-21-19(11-12-26(14)21)22(27)24-17-7-9-18(28-2)10-8-17;1-13-10-19(23-15-11-16-6-7-17(12-15)28-16)24-20-18(8-9-26(13)20)21(27)25-22(2,3)14-4-5-14;1-13-12-16(25-10-7-20(21,22)8-11-25)23-17-15(6-9-26(13)17)18(27)24-19(2,3)14-4-5-14;1-20(2,14-5-6-14)23-19(25)16-9-11-24-12-10-17(22-18(16)24)13-3-7-15(21)8-4-13;1-13-11-17(14-5-4-9-21-12-14)22-18-16(8-10-24(13)18)19(25)23-20(2,3)15-6-7-15;1-12(13-2-3-13)21-19(24)16-8-10-23-11-9-17(22-18(16)23)14-4-6-15(20)7-5-14;1-12-11-15(16-20-8-4-9-21-16)22-17-14(7-10-24(12)17)18(25)23-19(2,3)13-5-6-13;1-12-8-16(13-9-20-11-21-10-13)22-17-15(6-7-24(12)17)18(25)23-19(2,3)14-4-5-14/h3-6,11-13,17-18H,7-10H2,1-2H3,(H,24,27);8-10,14-17H,4-7,11-12H2,1-3H3,(H,23,24)(H,25,27);6,9,12,14H,4-5,7-8,10-11H2,1-3H3,(H,24,27);3-4,7-12,14H,5-6H2,1-2H3,(H,23,25);4-5,8-12,15H,6-7H2,1-3H3,(H,23,25);4-13H,2-3H2,1H3,(H,21,24);4,7-11,13H,5-6H2,1-3H3,(H,23,25);6-11,14H,4-5H2,1-3H3,(H,23,25)/t;;;;;12-;;/m.....0../s1.
What are the key properties of N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide?
N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide has a molecular weight of 2806.42 g/mol, XLogP of 29.00, 33 rotatable bonds, 9 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S)-1-cyclopropylethyl]-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4,4-difluoropiperidin-1-yl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(8-oxabicyclo[3.2.1]octan-3-ylamino)pyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-pyrimidin-5-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-(4-methoxycyclohexyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 157380388), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).