6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one

C160H105ClN26O8S4 — CID 161275946

About 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one

6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one (PubChem CID 161275946) has the molecular formula C160H105ClN26O8S4 and a molecular weight of 2683.49 g/mol. Its IUPAC name is 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one.

Molecular Properties

• Compound Name: 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one
• PubChem CID: 161275946
• Molecular Formula: C160H105ClN26O8S4
• Molecular Weight: 2683.49 g/mol
• Exact Mass: 2680.72
• IUPAC Name: 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one
• SMILES: Cc1ccc(-c2nc3[nH]c(=O)c(-c4ccccn4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-c4cccnc4)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(-c4cccnc4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-c4ccncc4)cc3cc2-c2cc(Cl)c3ncccc3c2)o1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4ccccn4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4cccnc4)cc3cc2-c2ccc3ncccc3c2)s1
• InChI: InChI=1S/C27H17ClN4O2.C27H18N4O2.2C27H18N4OS.2C26H17N5OS/c1-15-4-5-23(34-15)25-20(18-11-17-3-2-8-30-24(17)22(28)14-18)12-19-13-21(16-6-9-29-10-7-16)27(33)32-26(19)31-25;2*1-16-6-9-24(33-16)25-21(17-7-8-23-18(12-17)4-3-11-29-23)13-20-14-22(19-5-2-10-28-15-19)27(32)31-26(20)30-25;1-16-7-10-24(33-16)25-20(17-8-9-22-18(13-17)5-4-12-28-22)14-19-15-21(23-6-2-3-11-29-23)27(32)31-26(19)30-25;1-15-29-14-23(33-15)24-20(16-6-7-22-17(10-16)4-3-9-28-22)11-19-12-21(18-5-2-8-27-13-18)26(32)31-25(19)30-24;1-15-29-14-23(33-15)24-19(16-7-8-21-17(11-16)5-4-10-27-21)12-18-13-20(22-6-2-3-9-28-22)26(32)31-25(18)30-24/h2-14H,1H3,(H,31,32,33);3*2-15H,1H3,(H,30,31,32);2*2-14H,1H3,(H,30,31,32)
• InChIKey: VELCBIASQNKCLL-UHFFFAOYSA-N
• XLogP: 35.93
• TPSA: 481.24 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 32
• Rotatable Bonds: 18
• Heavy Atoms: 199
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2683.49
LogP ≤ 5	35.93
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?

The IUPAC name of 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one (CID 161275946) is 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one.

What is the SMILES notation for 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?

The canonical SMILES for 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one is Cc1ccc(-c2nc3[nH]c(=O)c(-c4ccccn4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-c4cccnc4)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(-c4cccnc4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(-c4ccncc4)cc3cc2-c2cc(Cl)c3ncccc3c2)o1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4ccccn4)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(-c4cccnc4)cc3cc2-c2ccc3ncccc3c2)s1.

What is the InChIKey of 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?

The InChIKey is VELCBIASQNKCLL-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H17ClN4O2.C27H18N4O2.2C27H18N4OS.2C26H17N5OS/c1-15-4-5-23(34-15)25-20(18-11-17-3-2-8-30-24(17)22(28)14-18)12-19-13-21(16-6-9-29-10-7-16)27(33)32-26(19)31-25;2*1-16-6-9-24(33-16)25-21(17-7-8-23-18(12-17)4-3-11-29-23)13-20-14-22(19-5-2-10-28-15-19)27(32)31-26(20)30-25;1-16-7-10-24(33-16)25-20(17-8-9-22-18(13-17)5-4-12-28-22)14-19-15-21(23-6-2-3-11-29-23)27(32)31-26(19)30-25;1-15-29-14-23(33-15)24-20(16-6-7-22-17(10-16)4-3-9-28-22)11-19-12-21(18-5-2-8-27-13-18)26(32)31-25(19)30-24;1-15-29-14-23(33-15)24-19(16-7-8-21-17(11-16)5-4-10-27-21)12-18-13-20(22-6-2-3-9-28-22)26(32)31-25(18)30-24/h2-14H,1H3,(H,31,32,33);3*2-15H,1H3,(H,30,31,32);2*2-14H,1H3,(H,30,31,32).

What are the key properties of 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one?

6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one has a molecular weight of 2683.49 g/mol, XLogP of 35.93, 18 rotatable bonds, 6 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(8-chloroquinolin-6-yl)-7-(5-methylfuran-2-yl)-3-pyridin-4-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(2-methyl-1,3-thiazol-5-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-2-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylthiophen-2-yl)-3-pyridin-3-yl-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one is sourced from PubChem (CID 161275946), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).