6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide

C73H72N20O7 — CID 161295628

IUPAC6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide
SMILESCOCc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)C)cc4c3)n2)c1.COCc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N5CCn6ccnc6C5)cc4c3)n2)c1.COc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)CC5(C)COC5)cc4c3)n2)c1
InChIInChI=1S/C26H24N8O2.C25H26N6O3.C22H22N6O2/c1-36-16-17-4-6-27-22(12-17)21-5-7-29-26(32-21)30-19-2-3-20-18(13-19)14-23(31-20)25(35)34-11-10-33-9-8-28-24(33)15-34;1-25(14-34-15-25)13-31(2)23(32)22-11-16-10-17(4-5-19(16)29-22)28-24-27-9-7-20(30-24)21-12-18(33-3)6-8-26-21;1-28(2)21(29)20-12-15-11-16(4-5-17(15)26-20)25-22-24-9-7-18(27-22)19-10-14(13-30-3)6-8-23-19/h2-9,12-14,31H,10-11,15-16H2,1H3,(H,29,30,32);4-12,29H,13-15H2,1-3H3,(H,27,28,30);4-12,26H,13H2,1-3H3,(H,24,25,27)
InChIKeyVGXWZQMQPFDCKI-UHFFFAOYSA-N
MW1341.51 g/mol
LogP11.25
Rot. Bonds19

About 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide

6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide (PubChem CID 161295628) has the molecular formula C73H72N20O7 and a molecular weight of 1341.51 g/mol. Its IUPAC name is 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide.

Molecular Properties

Compound Name6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide
PubChem CID161295628
Molecular FormulaC73H72N20O7
Molecular Weight1341.51 g/mol
Exact Mass1340.59
IUPAC Name6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide
SMILESCOCc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)C)cc4c3)n2)c1.COCc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N5CCn6ccnc6C5)cc4c3)n2)c1.COc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)CC5(C)COC5)cc4c3)n2)c1
InChIInChI=1S/C26H24N8O2.C25H26N6O3.C22H22N6O2/c1-36-16-17-4-6-27-22(12-17)21-5-7-29-26(32-21)30-19-2-3-20-18(13-19)14-23(31-20)25(35)34-11-10-33-9-8-28-24(33)15-34;1-25(14-34-15-25)13-31(2)23(32)22-11-16-10-17(4-5-19(16)29-22)28-24-27-9-7-20(30-24)21-12-18(33-3)6-8-26-21;1-28(2)21(29)20-12-15-11-16(4-5-17(15)26-20)25-22-24-9-7-18(27-22)19-10-14(13-30-3)6-8-23-19/h2-9,12-14,31H,10-11,15-16H2,1H3,(H,29,30,32);4-12,29H,13-15H2,1-3H3,(H,27,28,30);4-12,26H,13H2,1-3H3,(H,24,25,27)
InChIKeyVGXWZQMQPFDCKI-UHFFFAOYSA-N
XLogP11.25
TPSA315.14 Ų
H-Bond Donors6
H-Bond Acceptors21
Rotatable Bonds19
Heavy Atoms100
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001341.51
LogP ≤ 511.25
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1021

Analyze 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]methyl]-1H-indol-2-yl]methanone
CID 161304597
[5-[[4-[4-(iodomethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]-(4-methylpiperazin-1-yl)methanone
CID 89395487
[5-[[4-(4-butoxy-2-pyridinyl)pyrimidin-2-yl]amino]-1H-indol-2-yl]-morpholin-4-ylmethanone
CID 71233763
[5-[[4-[4-(3-hydroxy-2-methylpropoxy)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]-(4-methylpiperazin-1-yl)methanone
CID 71235779
[5-[[4-[4-[(2R)-3-methoxybutan-2-yl]oxy-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]-(4-methylpiperazin-1-yl)methanone
CID 71235860
[5-[[4-[4-(2-ethyl-3-hydroxyhexoxy)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]-(4-methylpiperazin-1-yl)methanone
CID 71233675
[5-[[4-[4-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]-(4-methylpiperazin-1-yl)methanone
CID 71233659
[4-(2-methoxyethyl)piperazin-1-yl]-[5-[(4-pyridin-2-ylpyrimidin-2-yl)amino]-1H-indol-2-yl]methanone
CID 71233752
(4-methylpiperazin-1-yl)-[5-[[4-(4-methyl-2-pyridinyl)pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone
CID 71233837
5-[[4-[4-(1,1-difluoroethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide
CID 71233777
[4-[2-(4-methylpiperazin-1-yl)ethyl]piperazin-1-yl]-[5-[(4-pyridin-2-ylpyrimidin-2-yl)amino]-1H-indol-2-yl]methanone
CID 71233665
[4-(oxan-4-ylmethyl)piperidin-1-yl]-[5-[(4-pyridin-2-ylpyrimidin-2-yl)amino]-1H-indol-2-yl]methanone
CID 123649106

Frequently Asked Questions

What is the IUPAC name of 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide?
The IUPAC name of 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide (CID 161295628) is 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide.
What is the SMILES notation for 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide?
The canonical SMILES for 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide is COCc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)C)cc4c3)n2)c1.COCc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N5CCn6ccnc6C5)cc4c3)n2)c1.COc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)CC5(C)COC5)cc4c3)n2)c1.
What is the InChIKey of 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide?
The InChIKey is VGXWZQMQPFDCKI-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H24N8O2.C25H26N6O3.C22H22N6O2/c1-36-16-17-4-6-27-22(12-17)21-5-7-29-26(32-21)30-19-2-3-20-18(13-19)14-23(31-20)25(35)34-11-10-33-9-8-28-24(33)15-34;1-25(14-34-15-25)13-31(2)23(32)22-11-16-10-17(4-5-19(16)29-22)28-24-27-9-7-20(30-24)21-12-18(33-3)6-8-26-21;1-28(2)21(29)20-12-15-11-16(4-5-17(15)26-20)25-22-24-9-7-18(27-22)19-10-14(13-30-3)6-8-23-19/h2-9,12-14,31H,10-11,15-16H2,1H3,(H,29,30,32);4-12,29H,13-15H2,1-3H3,(H,27,28,30);4-12,26H,13H2,1-3H3,(H,24,25,27).
What are the key properties of 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide?
6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide has a molecular weight of 1341.51 g/mol, XLogP of 11.25, 19 rotatable bonds, 6 hydrogen bond donors, and 21 hydrogen bond acceptors.
Where does this data come from?
All data for 6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl-[5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-1H-indol-2-yl]methanone;5-[[4-[4-(methoxymethyl)-2-pyridinyl]pyrimidin-2-yl]amino]-N,N-dimethyl-1H-indole-2-carboxamide;5-[[4-(4-methoxy-2-pyridinyl)pyrimidin-2-yl]amino]-N-methyl-N-[(3-methyloxetan-3-yl)methyl]-1H-indole-2-carboxamide is sourced from PubChem (CID 161295628), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).