1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine

C111H132BCl8F6N21O11Si — CID 161322068

About 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine

1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine (PubChem CID 161322068) has the molecular formula C111H132BCl8F6N21O11Si and a molecular weight of 2372.92 g/mol. Its IUPAC name is 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine.

Molecular Properties

• Compound Name: 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine
• PubChem CID: 161322068
• Molecular Formula: C111H132BCl8F6N21O11Si
• Molecular Weight: 2372.92 g/mol
• Exact Mass: 2367.77
• IUPAC Name: 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine
• SMILES: CC(C)c1nccc(CCCO)c1-n1c(=O)nc(N2CCCC[C@@H]2C)c2cc(F)c(Cl)nc21.CC(C)c1nccc(CCCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)[nH]c(=O)c2cc(F)c(Cl)nc21.CC1(C)OB(c2c(F)cccc2C#N)OC1(C)C.CCCCc1ccnc(C(C)C)c1-n1c(=O)nc(Cl)c2cc(F)c(Cl)nc21.CCCCc1ccnc(C(C)C)c1NC(=O)NC(=O)c1cc(F)c(Cl)nc1Cl.C[C@H]1CCCCN1.NC(=O)c1cc(F)c(Cl)nc1Cl
• InChI: InChI=1S/C24H29ClFN5O2.C24H32ClFN4O3Si.C19H21Cl2FN4O2.C19H19Cl2FN4O.C13H15BFNO2.C6H3Cl2FN2O.C6H13N/c1-14(2)19-20(16(8-6-12-32)9-10-27-19)31-23-17(13-18(26)21(25)28-23)22(29-24(31)33)30-11-5-4-7-15(30)3;1-14(2)18-19(15(10-11-27-18)9-8-12-33-34(6,7)24(3,4)5)30-21-16(22(31)29-23(30)32)13-17(26)20(25)28-21;1-4-5-6-11-7-8-23-14(10(2)3)15(11)24-19(28)26-18(27)12-9-13(22)17(21)25-16(12)20;1-4-5-6-11-7-8-23-14(10(2)3)15(11)26-18-12(16(20)25-19(26)27)9-13(22)17(21)24-18;1-12(2)13(3,4)18-14(17-12)11-9(8-16)6-5-7-10(11)15;7-4-2(6(10)12)1-3(9)5(8)11-4;1-6-4-2-3-5-7-6/h9-10,13-15,32H,4-8,11-12H2,1-3H3;10-11,13-14H,8-9,12H2,1-7H3,(H,29,31,32);7-10H,4-6H2,1-3H3,(H2,24,26,27,28);7-10H,4-6H2,1-3H3;5-7H,1-4H3;1H,(H2,10,12);6-7H,2-5H2,1H3/t15-;;;;;;6-/m0.....0/s1
• InChIKey: VKGUUGZVXLFPSJ-ASJREEBESA-N
• XLogP: 24.94
• TPSA: 428.92 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 28
• Rotatable Bonds: 26
• Heavy Atoms: 159
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2372.92
LogP ≤ 5	24.94
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine?

The IUPAC name of 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine (CID 161322068) is 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine.

What is the SMILES notation for 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine?

The canonical SMILES for 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine is CC(C)c1nccc(CCCO)c1-n1c(=O)nc(N2CCCC[C@@H]2C)c2cc(F)c(Cl)nc21.CC(C)c1nccc(CCCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)[nH]c(=O)c2cc(F)c(Cl)nc21.CC1(C)OB(c2c(F)cccc2C#N)OC1(C)C.CCCCc1ccnc(C(C)C)c1-n1c(=O)nc(Cl)c2cc(F)c(Cl)nc21.CCCCc1ccnc(C(C)C)c1NC(=O)NC(=O)c1cc(F)c(Cl)nc1Cl.C[C@H]1CCCCN1.NC(=O)c1cc(F)c(Cl)nc1Cl.

What is the InChIKey of 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine?

The InChIKey is VKGUUGZVXLFPSJ-ASJREEBESA-N. The full InChI is InChI=1S/C24H29ClFN5O2.C24H32ClFN4O3Si.C19H21Cl2FN4O2.C19H19Cl2FN4O.C13H15BFNO2.C6H3Cl2FN2O.C6H13N/c1-14(2)19-20(16(8-6-12-32)9-10-27-19)31-23-17(13-18(26)21(25)28-23)22(29-24(31)33)30-11-5-4-7-15(30)3;1-14(2)18-19(15(10-11-27-18)9-8-12-33-34(6,7)24(3,4)5)30-21-16(22(31)29-23(30)32)13-17(26)20(25)28-21;1-4-5-6-11-7-8-23-14(10(2)3)15(11)24-19(28)26-18(27)12-9-13(22)17(21)25-16(12)20;1-4-5-6-11-7-8-23-14(10(2)3)15(11)26-18-12(16(20)25-19(26)27)9-13(22)17(21)24-18;1-12(2)13(3,4)18-14(17-12)11-9(8-16)6-5-7-10(11)15;7-4-2(6(10)12)1-3(9)5(8)11-4;1-6-4-2-3-5-7-6/h9-10,13-15,32H,4-8,11-12H2,1-3H3;10-11,13-14H,8-9,12H2,1-7H3,(H,29,31,32);7-10H,4-6H2,1-3H3,(H2,24,26,27,28);7-10H,4-6H2,1-3H3;5-7H,1-4H3;1H,(H2,10,12);6-7H,2-5H2,1H3/t15-;;;;;;6-/m0.....0/s1.

What are the key properties of 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine?

1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine has a molecular weight of 2372.92 g/mol, XLogP of 24.94, 26 rotatable bonds, 6 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;N-[(4-butyl-2-propan-2-yl-3-pyridinyl)carbamoyl]-2,6-dichloro-5-fluoropyridine-3-carboxamide;1-(4-butyl-2-propan-2-yl-3-pyridinyl)-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;7-chloro-6-fluoro-1-[4-(3-hydroxypropyl)-2-propan-2-yl-3-pyridinyl]-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;2,6-dichloro-5-fluoropyridine-3-carboxamide;3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;(2S)-2-methylpiperidine is sourced from PubChem (CID 161322068), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).