1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine

C105H137BCl7F5N18O11Si3 — CID 159916759

About 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine

1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine (PubChem CID 159916759) has the molecular formula C105H137BCl7F5N18O11Si3 and a molecular weight of 2265.60 g/mol. Its IUPAC name is 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine.

Molecular Properties

• Compound Name: 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine
• PubChem CID: 159916759
• Molecular Formula: C105H137BCl7F5N18O11Si3
• Molecular Weight: 2265.60 g/mol
• Exact Mass: 2260.79
• IUPAC Name: 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine
• SMILES: CC(C)c1nccc(CCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)[nH]c(=O)c2cc(F)c(Cl)nc21.CC(C)c1nccc(CCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)nc(Cl)c2cc(F)c(Cl)nc21.CC(C)c1nccc(CCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)nc(N2CCCC[C@@H]2C)c2cc(F)c(Cl)nc21.CCCc1ccnc(C(C)C)c1NC(=O)NC(=O)c1cc(F)c(Cl)nc1Cl.C[C@H]1CCCCN1.OB(O)c1c(F)cccc1Cl
• InChI: InChI=1S/C29H41ClFN5O2Si.C23H29Cl2FN4O2Si.C23H30ClFN4O3Si.C18H19Cl2FN4O2.C6H5BClFO2.C6H13N/c1-18(2)23-24(20(12-14-32-23)13-16-38-39(7,8)29(4,5)6)36-27-21(17-22(31)25(30)33-27)26(34-28(36)37)35-15-10-9-11-19(35)3;1-13(2)17-18(14(8-10-27-17)9-11-32-33(6,7)23(3,4)5)30-21-15(19(24)29-22(30)31)12-16(26)20(25)28-21;1-13(2)17-18(14(8-10-26-17)9-11-32-33(6,7)23(3,4)5)29-20-15(21(30)28-22(29)31)12-16(25)19(24)27-20;1-4-5-10-6-7-22-13(9(2)3)14(10)23-18(27)25-17(26)11-8-12(21)16(20)24-15(11)19;8-4-2-1-3-5(9)6(4)7(10)11;1-6-4-2-3-5-7-6/h12,14,17-19H,9-11,13,15-16H2,1-8H3;8,10,12-13H,9,11H2,1-7H3;8,10,12-13H,9,11H2,1-7H3,(H,28,30,31);6-9H,4-5H2,1-3H3,(H2,23,25,26,27);1-3,10-11H;6-7H,2-5H2,1H3/t19-;;;;;6-/m0....0/s1
• InChIKey: NXWOGIZEIVNRHK-VASSWDOISA-N
• XLogP: 24.56
• TPSA: 369.38 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 26
• Rotatable Bonds: 25
• Heavy Atoms: 150
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2265.60
LogP ≤ 5	24.56
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine?

The IUPAC name of 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine (CID 159916759) is 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine.

What is the SMILES notation for 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine?

The canonical SMILES for 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine is CC(C)c1nccc(CCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)[nH]c(=O)c2cc(F)c(Cl)nc21.CC(C)c1nccc(CCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)nc(Cl)c2cc(F)c(Cl)nc21.CC(C)c1nccc(CCO[Si](C)(C)C(C)(C)C)c1-n1c(=O)nc(N2CCCC[C@@H]2C)c2cc(F)c(Cl)nc21.CCCc1ccnc(C(C)C)c1NC(=O)NC(=O)c1cc(F)c(Cl)nc1Cl.C[C@H]1CCCCN1.OB(O)c1c(F)cccc1Cl.

What is the InChIKey of 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine?

The InChIKey is NXWOGIZEIVNRHK-VASSWDOISA-N. The full InChI is InChI=1S/C29H41ClFN5O2Si.C23H29Cl2FN4O2Si.C23H30ClFN4O3Si.C18H19Cl2FN4O2.C6H5BClFO2.C6H13N/c1-18(2)23-24(20(12-14-32-23)13-16-38-39(7,8)29(4,5)6)36-27-21(17-22(31)25(30)33-27)26(34-28(36)37)35-15-10-9-11-19(35)3;1-13(2)17-18(14(8-10-27-17)9-11-32-33(6,7)23(3,4)5)30-21-15(19(24)29-22(30)31)12-16(26)20(25)28-21;1-13(2)17-18(14(8-10-26-17)9-11-32-33(6,7)23(3,4)5)29-20-15(21(30)28-22(29)31)12-16(25)19(24)27-20;1-4-5-10-6-7-22-13(9(2)3)14(10)23-18(27)25-17(26)11-8-12(21)16(20)24-15(11)19;8-4-2-1-3-5(9)6(4)7(10)11;1-6-4-2-3-5-7-6/h12,14,17-19H,9-11,13,15-16H2,1-8H3;8,10,12-13H,9,11H2,1-7H3;8,10,12-13H,9,11H2,1-7H3,(H,28,30,31);6-9H,4-5H2,1-3H3,(H2,23,25,26,27);1-3,10-11H;6-7H,2-5H2,1H3/t19-;;;;;6-/m0....0/s1.

What are the key properties of 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine?

1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine has a molecular weight of 2265.60 g/mol, XLogP of 24.56, 25 rotatable bonds, 6 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoro-4-[(2S)-2-methylpiperidin-1-yl]pyrido[2,3-d]pyrimidin-2-one;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-7-chloro-6-fluoropyrido[2,3-d]pyrimidine-2,4-dione;1-[4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-propan-2-yl-3-pyridinyl]-4,7-dichloro-6-fluoropyrido[2,3-d]pyrimidin-2-one;(2-chloro-6-fluorophenyl)boronic acid;2,6-dichloro-5-fluoro-N-[(2-propan-2-yl-4-propyl-3-pyridinyl)carbamoyl]pyridine-3-carboxamide;(2S)-2-methylpiperidine is sourced from PubChem (CID 159916759), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).