N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen

C146H146F8N30O17S6 — CID 161363427

IUPACN-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen
SMILESCC(C)(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2CC2CC2)cn1.CC(C)(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)cn1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C#N)cc3n2C2CCC2)nc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)nc1.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cn2)n(CC2CC2)c2cc(OC(F)F)ccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CC(F)F)ccc12.[H][H].[H][H].[H][H]
InChIInChI=1S/C27H24N6O3S.C26H26N6O3S.C25H24N6O3S.C23H22F4N4O2S.C23H24F2N4O3S.C22H20F2N4O3S.3H2/c1-2-13-37(34,35)32-19-8-11-24(31-17-19)26-23(16-29)22-10-9-21(14-25(22)33(26)20-6-3-7-20)36-27-18(15-28)5-4-12-30-27;1-26(2,3)36(33,34)31-23-11-8-17(16-30-23)24-21(15-27)20-10-9-19(35-25-28-12-5-13-29-25)14-22(20)32(24)18-6-4-7-18;1-2-13-35(32,33)30-17-7-10-22(29-16-17)24-21(15-26)20-9-8-19(34-25-27-11-4-12-28-25)14-23(20)31(24)18-5-3-6-18;24-10-15(11-25)30-34(32,33)17-5-7-20(29-13-17)23-19(12-28)18-6-4-14(9-22(26)27)8-21(18)31(23)16-2-1-3-16;1-23(2,3)33(30,31)28-20-9-6-15(12-27-20)21-18(11-26)17-8-7-16(32-22(24)25)10-19(17)29(21)13-14-4-5-14;23-22(24)31-15-4-7-17-18(10-25)21(28(20(17)9-15)12-13-1-2-13)19-8-3-14(11-26-19)27-32(29,30)16-5-6-16;;;/h4-5,8-12,14,17,20,32H,2-3,6-7,13H2,1H3;5,8-14,16,18H,4,6-7H2,1-3H3,(H,30,31);4,7-12,14,16,18,30H,2-3,5-6,13H2,1H3;4-8,13,15-16,22,30H,1-3,9-11H2;6-10,12,14,22H,4-5,13H2,1-3H3,(H,27,28);3-4,7-9,11,13,16,22,27H,1-2,5-6,12H2;3*1H
InChIKeyVPMKRCLLDDTKPP-UHFFFAOYSA-N
MW2937.35 g/mol
LogP31.02
Rot. Bonds46

About N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen

N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen (PubChem CID 161363427) has the molecular formula C146H146F8N30O17S6 and a molecular weight of 2937.35 g/mol. Its IUPAC name is N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen.

Molecular Properties

Compound NameN-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen
PubChem CID161363427
Molecular FormulaC146H146F8N30O17S6
Molecular Weight2937.35 g/mol
Exact Mass2934.97
IUPAC NameN-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen
SMILESCC(C)(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2CC2CC2)cn1.CC(C)(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)cn1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C#N)cc3n2C2CCC2)nc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)nc1.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cn2)n(CC2CC2)c2cc(OC(F)F)ccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CC(F)F)ccc12.[H][H].[H][H].[H][H]
InChIInChI=1S/C27H24N6O3S.C26H26N6O3S.C25H24N6O3S.C23H22F4N4O2S.C23H24F2N4O3S.C22H20F2N4O3S.3H2/c1-2-13-37(34,35)32-19-8-11-24(31-17-19)26-23(16-29)22-10-9-21(14-25(22)33(26)20-6-3-7-20)36-27-18(15-28)5-4-12-30-27;1-26(2,3)36(33,34)31-23-11-8-17(16-30-23)24-21(15-27)20-10-9-19(35-25-28-12-5-13-29-25)14-22(20)32(24)18-6-4-7-18;1-2-13-35(32,33)30-17-7-10-22(29-16-17)24-21(15-26)20-9-8-19(34-25-27-11-4-12-28-25)14-23(20)31(24)18-5-3-6-18;24-10-15(11-25)30-34(32,33)17-5-7-20(29-13-17)23-19(12-28)18-6-4-14(9-22(26)27)8-21(18)31(23)16-2-1-3-16;1-23(2,3)33(30,31)28-20-9-6-15(12-27-20)21-18(11-26)17-8-7-16(32-22(24)25)10-19(17)29(21)13-14-4-5-14;23-22(24)31-15-4-7-17-18(10-25)21(28(20(17)9-15)12-13-1-2-13)19-8-3-14(11-26-19)27-32(29,30)16-5-6-16;;;/h4-5,8-12,14,17,20,32H,2-3,6-7,13H2,1H3;5,8-14,16,18H,4,6-7H2,1-3H3,(H,30,31);4,7-12,14,16,18,30H,2-3,5-6,13H2,1H3;4-8,13,15-16,22,30H,1-3,9-11H2;6-10,12,14,22H,4-5,13H2,1-3H3,(H,27,28);3-4,7-9,11,13,16,22,27H,1-2,5-6,12H2;3*1H
InChIKeyVPMKRCLLDDTKPP-UHFFFAOYSA-N
XLogP31.02
TPSA661.07 Ų
H-Bond Donors6
H-Bond Acceptors41
Rotatable Bonds46
Heavy Atoms207
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002937.35
LogP ≤ 531.02
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1041

Analyze N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen with MolForge

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Related Compounds

6-(5-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-(3,3-difluorocyclobutyl)pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-(3,3-difluorocyclobutyl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-(3,3-difluorocyclobutyl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(3,3-difluorocyclobutyl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-(3,3-difluorocyclobutyl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen
CID 157065289
CID 157153677
CID 157153677
1-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-3-propan-2-ylurea;1-cyclobutyl-2-[2-(propan-2-ylamino)pyrimidin-5-yl]-6-pyrimidin-2-yloxyindole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate;2-[4-[1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]-1,2-thiazolidine 1,1-dioxide;propan-2-yl N-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[5-[1-(azetidin-1-yl)-3-cyano-6-pyrimidin-2-yloxy-1H-inden-2-yl]-2-pyridinyl]carbamate
CID 157159756
N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]propane-1-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]-3-propan-2-ylurea;1-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]-3-propan-2-ylurea;N-[4-[3-cyano-1-cyclopropyl-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(2,2-difluoroethoxy)indol-2-yl]phenyl]carbamate
CID 157180987
N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate
CID 157210131
CID 157214734
CID 157214734
N-[4-[3-cyano-1-cyclobutyl-6-(4-methoxy-3-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(2-methylpyrazol-3-yl)indol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(pyrimidin-2-ylamino)indol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-(2-fluoroethoxy)-2-[4-[(4-methyl-1,3-thiazol-2-yl)amino]phenyl]indole-3-carbonitrile
CID 157242210
6-[3-cyano-1-cyclobutyl-5-(2,2-difluoroethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclobutyl-6-(difluoromethoxy)-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
CID 157263261
N-[4-[3-cyano-1-(cyclopropylmethyl)-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(4-methylpyrimidin-2-yl)oxyindol-2-yl]-3-methylphenyl]carbamate;1-(cyclopropylmethyl)-6-(2-methylsulfonylethoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-(cyclopropylmethyl)-6-(3-methylsulfonylpropoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate
CID 157344993
6-[3-cyano-6-(difluoromethoxy)-5-fluoro-1-(2-methylpropyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-5-fluoro-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-ethyl-5-fluoro-1-(4-methyl-2-pyridinyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-ethyl-5-fluoro-1-(1,3-thiazol-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-4-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-5-fluoro-6-methyl-1-(1,3-thiazol-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
CID 157354691
bis(N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide);N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrazin-2-yloxyindol-2-yl]phenyl]carbamate
CID 157377299
6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-(3-cyano-1-cyclopentyl-5-fluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-pyrimidin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
CID 157431135

Frequently Asked Questions

What is the IUPAC name of N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen?
The IUPAC name of N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen (CID 161363427) is N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen.
What is the SMILES notation for N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen?
The canonical SMILES for N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen is CC(C)(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2CC2CC2)cn1.CC(C)(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)cn1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C#N)cc3n2C2CCC2)nc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)nc1.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cn2)n(CC2CC2)c2cc(OC(F)F)ccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CC(F)F)ccc12.[H][H].[H][H].[H][H].
What is the InChIKey of N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen?
The InChIKey is VPMKRCLLDDTKPP-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H24N6O3S.C26H26N6O3S.C25H24N6O3S.C23H22F4N4O2S.C23H24F2N4O3S.C22H20F2N4O3S.3H2/c1-2-13-37(34,35)32-19-8-11-24(31-17-19)26-23(16-29)22-10-9-21(14-25(22)33(26)20-6-3-7-20)36-27-18(15-28)5-4-12-30-27;1-26(2,3)36(33,34)31-23-11-8-17(16-30-23)24-21(15-27)20-10-9-19(35-25-28-12-5-13-29-25)14-22(20)32(24)18-6-4-7-18;1-2-13-35(32,33)30-17-7-10-22(29-16-17)24-21(15-26)20-9-8-19(34-25-27-11-4-12-28-25)14-23(20)31(24)18-5-3-6-18;24-10-15(11-25)30-34(32,33)17-5-7-20(29-13-17)23-19(12-28)18-6-4-14(9-22(26)27)8-21(18)31(23)16-2-1-3-16;1-23(2,3)33(30,31)28-20-9-6-15(12-27-20)21-18(11-26)17-8-7-16(32-22(24)25)10-19(17)29(21)13-14-4-5-14;23-22(24)31-15-4-7-17-18(10-25)21(28(20(17)9-15)12-13-1-2-13)19-8-3-14(11-26-19)27-32(29,30)16-5-6-16;;;/h4-5,8-12,14,17,20,32H,2-3,6-7,13H2,1H3;5,8-14,16,18H,4,6-7H2,1-3H3,(H,30,31);4,7-12,14,16,18,30H,2-3,5-6,13H2,1H3;4-8,13,15-16,22,30H,1-3,9-11H2;6-10,12,14,22H,4-5,13H2,1-3H3,(H,27,28);3-4,7-9,11,13,16,22,27H,1-2,5-6,12H2;3*1H.
What are the key properties of N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen?
N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen has a molecular weight of 2937.35 g/mol, XLogP of 31.02, 46 rotatable bonds, 6 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]-3-pyridinyl]propane-1-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(2,2-difluoroethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;N-[5-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-pyridinyl]-2-methylpropane-2-sulfonamide;N-[6-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-3-pyridinyl]propane-1-sulfonamide;N-[6-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-3-pyridinyl]cyclopropanesulfonamide;N-[5-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-2-pyridinyl]-2-methylpropane-2-sulfonamide;molecular hydrogen is sourced from PubChem (CID 161363427), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).