N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate

C169H159F3N28O15S3 — CID 161450980

About N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate

N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate (PubChem CID 161450980) has the molecular formula C169H159F3N28O15S3 and a molecular weight of 2975.51 g/mol. Its IUPAC name is N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate.

Molecular Properties

• Compound Name: N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate
• PubChem CID: 161450980
• Molecular Formula: C169H159F3N28O15S3
• Molecular Weight: 2975.51 g/mol
• Exact Mass: 2973.17
• IUPAC Name: N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate
• SMILES: CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4cc(C)ccn4)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C#N)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4nccnc4C#N)cc3n2C2CC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(N4CCCC4)cc3n2CC2CC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2CC2CC2)cc1)C(F)(F)F.Cc1ccc(-c2ccc3c(C#N)c(-c4ccc(NC(=O)O[C@H](C)C5CC5)cc4)n(C4CCC4)c3c2)nc1
• InChI: InChI=1S/C31H30N4O2.C29H32N4O2.C28H25N5O3S.C28H28N4O2S.C27H22F3N5O3.C26H22N6O3S/c1-19-6-15-28(33-18-19)23-11-14-26-27(17-32)30(35(29(26)16-23)25-4-3-5-25)22-9-12-24(13-10-22)34-31(36)37-20(2)21-7-8-21;1-19(21-6-7-21)35-29(34)31-23-10-8-22(9-11-23)28-26(17-30)25-13-12-24(32-14-2-3-15-32)16-27(25)33(28)18-20-4-5-20;1-2-15-37(34,35)32-21-10-8-19(9-11-21)27-25(18-30)24-13-12-23(16-26(24)33(27)22-6-3-7-22)36-28-20(17-29)5-4-14-31-28;1-3-15-35(33,34)31-22-10-7-20(8-11-22)28-25(18-29)24-12-9-21(26-16-19(2)13-14-30-26)17-27(24)32(28)23-5-4-6-23;1-16(27(28,29)30)37-26(36)34-19-7-5-18(6-8-19)24-22(14-31)21-10-9-20(38-25-32-11-2-12-33-25)13-23(21)35(24)15-17-3-4-17;1-2-13-36(33,34)31-18-5-3-17(4-6-18)25-22(15-27)21-10-9-20(14-24(21)32(25)19-7-8-19)35-26-23(16-28)29-11-12-30-26/h6,9-16,18,20-21,25H,3-5,7-8H2,1-2H3,(H,34,36);8-13,16,19-21H,2-7,14-15,18H2,1H3,(H,31,34);4-5,8-14,16,22,32H,2-3,6-7,15H2,1H3;7-14,16-17,23,31H,3-6,15H2,1-2H3;2,5-13,16-17H,3-4,15H2,1H3,(H,34,36);3-6,9-12,14,19,31H,2,7-8,13H2,1H3/t20-;19-;;;16-;/m11..1./s1
• InChIKey: WANIFJSCCLDXOD-USWAHEBMSA-N
• XLogP: 38.49
• TPSA: 594.56 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 37
• Rotatable Bonds: 43
• Heavy Atoms: 218
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2975.51
LogP ≤ 5	38.49
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	37

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '>_2_ester_groups', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate?

The IUPAC name of N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate (CID 161450980) is N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate.

What is the SMILES notation for N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate?

The canonical SMILES for N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate is CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(-c4cc(C)ccn4)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccc4C#N)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4nccnc4C#N)cc3n2C2CC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(N4CCCC4)cc3n2CC2CC2)cc1)C1CC1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2CC2CC2)cc1)C(F)(F)F.Cc1ccc(-c2ccc3c(C#N)c(-c4ccc(NC(=O)O[C@H](C)C5CC5)cc4)n(C4CCC4)c3c2)nc1.

What is the InChIKey of N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate?

The InChIKey is WANIFJSCCLDXOD-USWAHEBMSA-N. The full InChI is InChI=1S/C31H30N4O2.C29H32N4O2.C28H25N5O3S.C28H28N4O2S.C27H22F3N5O3.C26H22N6O3S/c1-19-6-15-28(33-18-19)23-11-14-26-27(17-32)30(35(29(26)16-23)25-4-3-5-25)22-9-12-24(13-10-22)34-31(36)37-20(2)21-7-8-21;1-19(21-6-7-21)35-29(34)31-23-10-8-22(9-11-23)28-26(17-30)25-13-12-24(32-14-2-3-15-32)16-27(25)33(28)18-20-4-5-20;1-2-15-37(34,35)32-21-10-8-19(9-11-21)27-25(18-30)24-13-12-23(16-26(24)33(27)22-6-3-7-22)36-28-20(17-29)5-4-14-31-28;1-3-15-35(33,34)31-22-10-7-20(8-11-22)28-25(18-29)24-12-9-21(26-16-19(2)13-14-30-26)17-27(24)32(28)23-5-4-6-23;1-16(27(28,29)30)37-26(36)34-19-7-5-18(6-8-19)24-22(14-31)21-10-9-20(38-25-32-11-2-12-33-25)13-23(21)35(24)15-17-3-4-17;1-2-13-36(33,34)31-18-5-3-17(4-6-18)25-22(15-27)21-10-9-20(14-24(21)32(25)19-7-8-19)35-26-23(16-28)29-11-12-30-26/h6,9-16,18,20-21,25H,3-5,7-8H2,1-2H3,(H,34,36);8-13,16,19-21H,2-7,14-15,18H2,1H3,(H,31,34);4-5,8-14,16,22,32H,2-3,6-7,15H2,1H3;7-14,16-17,23,31H,3-6,15H2,1-2H3;2,5-13,16-17H,3-4,15H2,1H3,(H,34,36);3-6,9-12,14,19,31H,2,7-8,13H2,1H3/t20-;19-;;;16-;/m11..1./s1.

What are the key properties of N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate?

N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate has a molecular weight of 2975.51 g/mol, XLogP of 38.49, 43 rotatable bonds, 6 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[3-cyano-6-(3-cyanopyrazin-2-yl)oxy-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-6-[(3-cyano-2-pyridinyl)oxy]-1-cyclobutylindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(4-methyl-2-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrrolidin-1-ylindol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]carbamate is sourced from PubChem (CID 161450980), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).