2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one

C89H100N26O6 — CID 161452259

About 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one

2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one (PubChem CID 161452259) has the molecular formula C89H100N26O6 and a molecular weight of 1629.95 g/mol. Its IUPAC name is 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one.

Molecular Properties

• Compound Name: 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one
• PubChem CID: 161452259
• Molecular Formula: C89H100N26O6
• Molecular Weight: 1629.95 g/mol
• Exact Mass: 1628.83
• IUPAC Name: 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one
• SMILES: CCN1CCC(c2cn3c(=O)cc(-c4ccc5nc(C)cn5c4)nc3cn2)CC1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCN(C)CC5)ncc4n3)ccc2n1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCN(CCO)CC5)ncc4n3)ccc2n1.Cc1cn2nc(-c3cc(=O)n4cc(N5CCC(N(C)CCO)CC5)nc(C)c4n3)cc2c(C)n1
• InChI: InChI=1S/C24H30N8O2.C22H24N6O2.C22H24N6O.C21H22N6O/c1-15-13-32-21(16(2)25-15)11-20(28-32)19-12-23(34)31-14-22(26-17(3)24(31)27-19)30-7-5-18(6-8-30)29(4)9-10-33;1-15-12-27-13-17(2-3-20(27)24-15)18-10-22(30)28-14-19(23-11-21(28)25-18)16-4-6-26(7-5-16)8-9-29;1-3-26-8-6-16(7-9-26)19-14-28-21(11-23-19)25-18(10-22(28)29)17-4-5-20-24-15(2)12-27(20)13-17;1-14-11-26-12-16(3-4-19(26)23-14)17-9-21(28)27-13-18(22-10-20(27)24-17)15-5-7-25(2)8-6-15/h11-14,18,33H,5-10H2,1-4H3;2-3,10-14,16,29H,4-9H2,1H3;4-5,10-14,16H,3,6-9H2,1-2H3;3-4,9-13,15H,5-8H2,1-2H3
• InChIKey: WARKBWDVEVAJNH-UHFFFAOYSA-N
• XLogP: 8.94
• TPSA: 327.79 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 32
• Rotatable Bonds: 14
• Heavy Atoms: 121
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1629.95
LogP ≤ 5	8.94
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one?

The IUPAC name of 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one (CID 161452259) is 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one.

What is the SMILES notation for 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one?

The canonical SMILES for 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one is CCN1CCC(c2cn3c(=O)cc(-c4ccc5nc(C)cn5c4)nc3cn2)CC1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCN(C)CC5)ncc4n3)ccc2n1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCN(CCO)CC5)ncc4n3)ccc2n1.Cc1cn2nc(-c3cc(=O)n4cc(N5CCC(N(C)CCO)CC5)nc(C)c4n3)cc2c(C)n1.

What is the InChIKey of 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one?

The InChIKey is WARKBWDVEVAJNH-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H30N8O2.C22H24N6O2.C22H24N6O.C21H22N6O/c1-15-13-32-21(16(2)25-15)11-20(28-32)19-12-23(34)31-14-22(26-17(3)24(31)27-19)30-7-5-18(6-8-30)29(4)9-10-33;1-15-12-27-13-17(2-3-20(27)24-15)18-10-22(30)28-14-19(23-11-21(28)25-18)16-4-6-26(7-5-16)8-9-29;1-3-26-8-6-16(7-9-26)19-14-28-21(11-23-19)25-18(10-22(28)29)17-4-5-20-24-15(2)12-27(20)13-17;1-14-11-26-12-16(3-4-19(26)23-14)17-9-21(28)27-13-18(22-10-20(27)24-17)15-5-7-25(2)8-6-15/h11-14,18,33H,5-10H2,1-4H3;2-3,10-14,16,29H,4-9H2,1H3;4-5,10-14,16H,3,6-9H2,1-2H3;3-4,9-13,15H,5-8H2,1-2H3.

What are the key properties of 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one?

2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one has a molecular weight of 1629.95 g/mol, XLogP of 8.94, 14 rotatable bonds, 2 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-[4-[2-hydroxyethyl(methyl)amino]piperidin-1-yl]-9-methylpyrazino[1,2-a]pyrimidin-4-one;7-(1-ethylpiperidin-4-yl)-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[1-(2-hydroxyethyl)piperidin-4-yl]-2-(2-methylimidazo[1,2-a]pyridin-6-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one is sourced from PubChem (CID 161452259), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).