2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one

C87H96N26O5 — CID 159565827

About 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one

2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one (PubChem CID 159565827) has the molecular formula C87H96N26O5 and a molecular weight of 1585.90 g/mol. Its IUPAC name is 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one.

Molecular Properties

• Compound Name: 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one
• PubChem CID: 159565827
• Molecular Formula: C87H96N26O5
• Molecular Weight: 1585.90 g/mol
• Exact Mass: 1584.81
• IUPAC Name: 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one
• SMILES: CCN1CCC(c2cn3c(=O)cc(-c4cc(C)c5nc(C)cn5c4)nc3cn2)CC1.CCN1CCN(c2cn3c(=O)cc(-c4ccc5nn(C)cc5c4)nc3cn2)CC1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCN(C)CC5)ncc4n3)cc(C)c2n1.Cn1cc2cc(-c3cc(=O)n4cc(N5CCN(CCO)CC5)ncc4n3)ccc2n1
• InChI: InChI=1S/C23H26N6O.C22H24N6O.C21H23N7O2.C21H23N7O/c1-4-27-7-5-17(6-8-27)20-14-29-21(11-24-20)26-19(10-22(29)30)18-9-15(2)23-25-16(3)12-28(23)13-18;1-14-8-17(12-27-11-15(2)24-22(14)27)18-9-21(29)28-13-19(23-10-20(28)25-18)16-4-6-26(3)7-5-16;1-25-13-16-10-15(2-3-17(16)24-25)18-11-21(30)28-14-20(22-12-19(28)23-18)27-6-4-26(5-7-27)8-9-29;1-3-26-6-8-27(9-7-26)20-14-28-19(12-22-20)23-18(11-21(28)29)15-4-5-17-16(10-15)13-25(2)24-17/h9-14,17H,4-8H2,1-3H3;8-13,16H,4-7H2,1-3H3;2-3,10-14,29H,4-9H2,1H3;4-5,10-14H,3,6-9H2,1-2H3
• InChIKey: MHEKGPXIXWNUEV-UHFFFAOYSA-N
• XLogP: 8.59
• TPSA: 298.95 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 31
• Rotatable Bonds: 12
• Heavy Atoms: 118
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1585.90
LogP ≤ 5	8.59
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one?

The IUPAC name of 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one (CID 159565827) is 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one.

What is the SMILES notation for 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one?

The canonical SMILES for 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one is CCN1CCC(c2cn3c(=O)cc(-c4cc(C)c5nc(C)cn5c4)nc3cn2)CC1.CCN1CCN(c2cn3c(=O)cc(-c4ccc5nn(C)cc5c4)nc3cn2)CC1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCN(C)CC5)ncc4n3)cc(C)c2n1.Cn1cc2cc(-c3cc(=O)n4cc(N5CCN(CCO)CC5)ncc4n3)ccc2n1.

What is the InChIKey of 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one?

The InChIKey is MHEKGPXIXWNUEV-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H26N6O.C22H24N6O.C21H23N7O2.C21H23N7O/c1-4-27-7-5-17(6-8-27)20-14-29-21(11-24-20)26-19(10-22(29)30)18-9-15(2)23-25-16(3)12-28(23)13-18;1-14-8-17(12-27-11-15(2)24-22(14)27)18-9-21(29)28-13-19(23-10-20(28)25-18)16-4-6-26(3)7-5-16;1-25-13-16-10-15(2-3-17(16)24-25)18-11-21(30)28-14-20(22-12-19(28)23-18)27-6-4-26(5-7-27)8-9-29;1-3-26-6-8-27(9-7-26)20-14-28-19(12-22-20)23-18(11-21(28)29)15-4-5-17-16(10-15)13-25(2)24-17/h9-14,17H,4-8H2,1-3H3;8-13,16H,4-7H2,1-3H3;2-3,10-14,29H,4-9H2,1H3;4-5,10-14H,3,6-9H2,1-2H3.

What are the key properties of 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one?

2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one has a molecular weight of 1585.90 g/mol, XLogP of 8.59, 12 rotatable bonds, 1 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-ethylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-(1-methylpiperidin-4-yl)pyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one is sourced from PubChem (CID 159565827), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).