N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide

C81H51Cl5F14N20O4 — CID 162045223

About N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide

N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide (PubChem CID 162045223) has the molecular formula C81H51Cl5F14N20O4 and a molecular weight of 1811.67 g/mol. Its IUPAC name is N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide
• PubChem CID: 162045223
• Molecular Formula: C81H51Cl5F14N20O4
• Molecular Weight: 1811.67 g/mol
• Exact Mass: 1808.26
• IUPAC Name: N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide
• SMILES: Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3c(F)cc(F)cc3[nH]2)c1.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)n1.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1cnc(Cl)c(-c2nc3ccccc3n2C)c1.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1cnc(Cl)c(-c2nc3ncc(Cl)cc3[nH]2)c1
• InChI: InChI=1S/C21H12ClF5N4O.C21H15ClF3N5O.C20H13ClF3N5O.C19H11Cl2F3N6O/c1-9-12(3-5-17(28-9)21(25,26)27)20(32)29-11-2-4-14(22)13(8-11)19-30-16-7-10(23)6-15(24)18(16)31-19;1-11-13(7-8-17(27-11)21(23,24)25)20(31)28-12-9-14(18(22)26-10-12)19-29-15-5-3-4-6-16(15)30(19)2;1-10-11(6-8-15(25-10)20(22,23)24)19(30)29-16-9-7-12(21)17(28-16)18-26-13-4-2-3-5-14(13)27-18;1-8-11(2-3-14(27-8)19(22,23)24)18(31)28-10-5-12(15(21)25-7-10)16-29-13-4-9(20)6-26-17(13)30-16/h2-8H,1H3,(H,29,32)(H,30,31);3-10H,1-2H3,(H,28,31);2-9H,1H3,(H,26,27)(H,28,29,30);2-7H,1H3,(H,28,31)(H,26,29,30)
• InChIKey: YXUIGFUMUUCLOE-UHFFFAOYSA-N
• XLogP: 21.95
• TPSA: 323.38 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 17
• Rotatable Bonds: 12
• Heavy Atoms: 124
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1811.67
LogP ≤ 5	21.95
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	17

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide?

The IUPAC name of N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide (CID 162045223) is N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide.

What is the SMILES notation for N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide?

The canonical SMILES for N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide is Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3c(F)cc(F)cc3[nH]2)c1.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)n1.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1cnc(Cl)c(-c2nc3ccccc3n2C)c1.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1cnc(Cl)c(-c2nc3ncc(Cl)cc3[nH]2)c1.

What is the InChIKey of N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide?

The InChIKey is YXUIGFUMUUCLOE-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H12ClF5N4O.C21H15ClF3N5O.C20H13ClF3N5O.C19H11Cl2F3N6O/c1-9-12(3-5-17(28-9)21(25,26)27)20(32)29-11-2-4-14(22)13(8-11)19-30-16-7-10(23)6-15(24)18(16)31-19;1-11-13(7-8-17(27-11)21(23,24)25)20(31)28-12-9-14(18(22)26-10-12)19-29-15-5-3-4-6-16(15)30(19)2;1-10-11(6-8-15(25-10)20(22,23)24)19(30)29-16-9-7-12(21)17(28-16)18-26-13-4-2-3-5-14(13)27-18;1-8-11(2-3-14(27-8)19(22,23)24)18(31)28-10-5-12(15(21)25-7-10)16-29-13-4-9(20)6-26-17(13)30-16/h2-8H,1H3,(H,29,32)(H,30,31);3-10H,1-2H3,(H,28,31);2-9H,1H3,(H,26,27)(H,28,29,30);2-7H,1H3,(H,28,31)(H,26,29,30).

What are the key properties of N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide?

N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide has a molecular weight of 1811.67 g/mol, XLogP of 21.95, 12 rotatable bonds, 7 hydrogen bond donors, and 17 hydrogen bond acceptors.

Where does this data come from?

All data for N-[6-(1H-benzimidazol-2-yl)-5-chloro-2-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[4-chloro-3-(4,6-difluoro-1H-benzimidazol-2-yl)phenyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide;N-[6-chloro-5-(1-methylbenzimidazol-2-yl)-3-pyridinyl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide is sourced from PubChem (CID 162045223), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).