N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide

C84H108N24O10S4 — CID 162052253

About N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide

N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide (PubChem CID 162052253) has the molecular formula C84H108N24O10S4 and a molecular weight of 1742.21 g/mol. Its IUPAC name is N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide.

Molecular Properties

• Compound Name: N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide
• PubChem CID: 162052253
• Molecular Formula: C84H108N24O10S4
• Molecular Weight: 1742.21 g/mol
• Exact Mass: 1740.76
• IUPAC Name: N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide
• SMILES: CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)CN(Cc2ccnc(C)c2)C(=O)N3)s1.CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(Cc2ccnc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)CN(Cc2ccnc(C)c2)C(=O)N3)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(Cc2ccnc(C)c2)C3=O)s1
• InChI: InChI=1S/2C21H26N6O3S.2C21H28N6O2S/c2*1-13-10-16(4-7-22-13)12-27-18(29)21(25-20(27)30)5-8-26(9-6-21)14(2)17-11-23-19(31-17)24-15(3)28;2*1-14-10-17(4-7-22-14)12-27-13-21(25-20(27)29)5-8-26(9-6-21)15(2)18-11-23-19(30-18)24-16(3)28/h2*4,7,10-11,14H,5-6,8-9,12H2,1-3H3,(H,25,30)(H,23,24,28);2*4,7,10-11,15H,5-6,8-9,12-13H2,1-3H3,(H,25,29)(H,23,24,28)/t2*14-;2*15-/m1010/s1
• InChIKey: YYRUTBFRCPXQCG-DDCZZNPLSA-N
• XLogP: 10.76
• TPSA: 395.98 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 26
• Rotatable Bonds: 20
• Heavy Atoms: 122
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1742.21
LogP ≤ 5	10.76
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The IUPAC name of N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide (CID 162052253) is N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide.

What is the SMILES notation for N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The canonical SMILES for N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide is CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)CN(Cc2ccnc(C)c2)C(=O)N3)s1.CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(Cc2ccnc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)CN(Cc2ccnc(C)c2)C(=O)N3)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(Cc2ccnc(C)c2)C3=O)s1.

What is the InChIKey of N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The InChIKey is YYRUTBFRCPXQCG-DDCZZNPLSA-N. The full InChI is InChI=1S/2C21H26N6O3S.2C21H28N6O2S/c2*1-13-10-16(4-7-22-13)12-27-18(29)21(25-20(27)30)5-8-26(9-6-21)14(2)17-11-23-19(31-17)24-15(3)28;2*1-14-10-17(4-7-22-14)12-27-13-21(25-20(27)29)5-8-26(9-6-21)15(2)18-11-23-19(30-18)24-16(3)28/h2*4,7,10-11,14H,5-6,8-9,12H2,1-3H3,(H,25,30)(H,23,24,28);2*4,7,10-11,15H,5-6,8-9,12-13H2,1-3H3,(H,25,29)(H,23,24,28)/t2*14-;2*15-/m1010/s1.

What are the key properties of N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide has a molecular weight of 1742.21 g/mol, XLogP of 10.76, 20 rotatable bonds, 8 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-[(2-methyl-4-pyridinyl)methyl]-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide is sourced from PubChem (CID 162052253), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).