8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide

C24H24F2N6OS — CID 162595791

IUPAC8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide
SMILESCc1ccc(-c2cnc3c(N4CCC(F)(F)CC4)cc(C(=O)NC4(c5ccn[nH]5)CC4)cn23)s1
InChIInChI=1S/C24H24F2N6OS/c1-15-2-3-19(34-15)18-13-27-21-17(31-10-7-24(25,26)8-11-31)12-16(14-32(18)21)22(33)29-23(5-6-23)20-4-9-28-30-20/h2-4,9,12-14H,5-8,10-11H2,1H3,(H,28,30)(H,29,33)
InChIKeyPYGDQOZHXCWZQM-UHFFFAOYSA-N
MW482.56 g/mol
LogP4.75
Rot. Bonds5

About 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide

8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide (PubChem CID 162595791) has the molecular formula C24H24F2N6OS and a molecular weight of 482.56 g/mol. Its IUPAC name is 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide.

Molecular Properties

Compound Name8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide
PubChem CID162595791
Molecular FormulaC24H24F2N6OS
Molecular Weight482.56 g/mol
Exact Mass482.17
IUPAC Name8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide
SMILESCc1ccc(-c2cnc3c(N4CCC(F)(F)CC4)cc(C(=O)NC4(c5ccn[nH]5)CC4)cn23)s1
InChIInChI=1S/C24H24F2N6OS/c1-15-2-3-19(34-15)18-13-27-21-17(31-10-7-24(25,26)8-11-31)12-16(14-32(18)21)22(33)29-23(5-6-23)20-4-9-28-30-20/h2-4,9,12-14H,5-8,10-11H2,1H3,(H,28,30)(H,29,33)
InChIKeyPYGDQOZHXCWZQM-UHFFFAOYSA-N
XLogP4.75
TPSA78.32 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500482.56
LogP ≤ 54.75
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

Analyze 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide?
The IUPAC name of 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide (CID 162595791) is 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide.
What is the SMILES notation for 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide?
The canonical SMILES for 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide is Cc1ccc(-c2cnc3c(N4CCC(F)(F)CC4)cc(C(=O)NC4(c5ccn[nH]5)CC4)cn23)s1.
What is the InChIKey of 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide?
The InChIKey is PYGDQOZHXCWZQM-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H24F2N6OS/c1-15-2-3-19(34-15)18-13-27-21-17(31-10-7-24(25,26)8-11-31)12-16(14-32(18)21)22(33)29-23(5-6-23)20-4-9-28-30-20/h2-4,9,12-14H,5-8,10-11H2,1H3,(H,28,30)(H,29,33).
What are the key properties of 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide?
8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide has a molecular weight of 482.56 g/mol, XLogP of 4.75, 5 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 8-(4,4-difluoropiperidin-1-yl)-3-(5-methylthiophen-2-yl)-N-[1-(1H-pyrazol-5-yl)cyclopropyl]imidazo[1,2-a]pyridine-6-carboxamide is sourced from PubChem (CID 162595791), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).