2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide

C18H22F3N3O3 — CID 163352384

IUPAC2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide
SMILESO=C(CN1CCOC(C(=O)N2CCC(F)(F)CC2)C1)Nc1ccccc1F
InChIInChI=1S/C18H22F3N3O3/c19-13-3-1-2-4-14(13)22-16(25)12-23-9-10-27-15(11-23)17(26)24-7-5-18(20,21)6-8-24/h1-4,15H,5-12H2,(H,22,25)
InChIKeyVHGDLQDPEGDGDX-UHFFFAOYSA-N
MW385.39 g/mol
LogP1.72
Rot. Bonds4

About 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide

2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide (PubChem CID 163352384) has the molecular formula C18H22F3N3O3 and a molecular weight of 385.39 g/mol. Its IUPAC name is 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide.

Molecular Properties

Compound Name2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide
PubChem CID163352384
Molecular FormulaC18H22F3N3O3
Molecular Weight385.39 g/mol
Exact Mass385.16
IUPAC Name2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide
SMILESO=C(CN1CCOC(C(=O)N2CCC(F)(F)CC2)C1)Nc1ccccc1F
InChIInChI=1S/C18H22F3N3O3/c19-13-3-1-2-4-14(13)22-16(25)12-23-9-10-27-15(11-23)17(26)24-7-5-18(20,21)6-8-24/h1-4,15H,5-12H2,(H,22,25)
InChIKeyVHGDLQDPEGDGDX-UHFFFAOYSA-N
XLogP1.72
TPSA61.88 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500385.39
LogP ≤ 51.72
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

Analyze 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]acetamide
CID 163349226
N-(2-fluorophenyl)-2-[2-[5-[(2-fluorophenyl)methyl]-2-pyridinyl]morpholin-4-yl]acetamide
CID 127250139
2-[4-[(3R)-2,3-dihydro-1,4-benzodioxine-3-carbonyl]piperazin-1-yl]-N-(2-fluorophenyl)acetamide
CID 9368491
2-[(3R)-3-aminopyrrolidin-1-yl]-N-(2-fluorophenyl)acetamide;hydrochloride
CID 119905386
2-(3-aminopyrrolidin-1-yl)-N-(2-fluorophenyl)acetamide;hydrochloride
CID 119917633
N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(pyrrolidine-1-carbonyl)morpholin-4-yl]acetamide
CID 163352409
2-[4-(cyclohexanecarbonyl)piperazin-1-yl]-N-(2-fluorophenyl)acetamide
CID 86850419
1-[2-(2-fluoroanilino)-2-oxoethyl]-3-methylpiperidine-3-carboxylic acid
CID 63136985
2-[4-(2-fluorobenzoyl)piperazin-1-yl]-N-(2-fluorophenyl)acetamide
CID 15999180
N-(2-fluorophenyl)-2-[3-(2-hydroxyethyl)pyrrolidin-1-yl]acetamide
CID 115648320
[4-[(2-fluorophenyl)methyl]morpholin-2-yl]-thiomorpholin-4-ylmethanone
CID 146078179
N-(2-fluorophenyl)-3-[2-(4-fluorophenyl)morpholin-4-yl]propanamide
CID 43065711

Frequently Asked Questions

What is the IUPAC name of 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide?
The IUPAC name of 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide (CID 163352384) is 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide.
What is the SMILES notation for 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide?
The canonical SMILES for 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide is O=C(CN1CCOC(C(=O)N2CCC(F)(F)CC2)C1)Nc1ccccc1F.
What is the InChIKey of 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide?
The InChIKey is VHGDLQDPEGDGDX-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H22F3N3O3/c19-13-3-1-2-4-14(13)22-16(25)12-23-9-10-27-15(11-23)17(26)24-7-5-18(20,21)6-8-24/h1-4,15H,5-12H2,(H,22,25).
What are the key properties of 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide?
2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide has a molecular weight of 385.39 g/mol, XLogP of 1.72, 4 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[2-(4,4-difluoropiperidine-1-carbonyl)morpholin-4-yl]-N-(2-fluorophenyl)acetamide is sourced from PubChem (CID 163352384), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).