About 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide
2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide (PubChem CID 163361470) has the molecular formula C25H21F4N3O5
and a molecular weight of 519.40 g/mol. Its IUPAC name is 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide.
Molecular Properties
| Compound Name | 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide |
| PubChem CID | 163361470 |
| Molecular Formula | C25H21F4N3O5 |
| Molecular Weight | 519.40 g/mol |
| Exact Mass | 519.14 |
| IUPAC Name | 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide |
| SMILES | COC1=NC=CC(=C1)NC(=O)C2=C(C=C(C(=C2)C(F)(F)F)C3CC3)OC4=C(C=C(C=C4)F)OCC(=O)N |
| InChI | InChI=1S/C25H21F4N3O5/c1-35-23-9-15(6-7-31-23)32-24(34)17-10-18(25(27,28)29)16(13-2-3-13)11-20(17)37-19-5-4-14(26)8-21(19)36-12-22(30)33/h4-11,13H,2-3,12H2,1H3,(H2,30,33)(H,31,32,34) |
| InChIKey | QWFYYCWKYHEEQS-UHFFFAOYSA-N |
| XLogP | 4.30 |
| TPSA | 113.00 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Heavy Atoms | 37 |
| Complexity | 799 |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 519.40 |
| LogP ≤ 5 | 4.30 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 10 |
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Frequently Asked Questions
What is the IUPAC name of 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide?
The IUPAC name of 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide (CID 163361470) is 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide.
What is the SMILES notation for 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide?
The canonical SMILES for 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide is COC1=NC=CC(=C1)NC(=O)C2=C(C=C(C(=C2)C(F)(F)F)C3CC3)OC4=C(C=C(C=C4)F)OCC(=O)N.
What is the InChIKey of 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide?
The InChIKey is QWFYYCWKYHEEQS-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H21F4N3O5/c1-35-23-9-15(6-7-31-23)32-24(34)17-10-18(25(27,28)29)16(13-2-3-13)11-20(17)37-19-5-4-14(26)8-21(19)36-12-22(30)33/h4-11,13H,2-3,12H2,1H3,(H2,30,33)(H,31,32,34).
What are the key properties of 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide?
2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide has a molecular weight of 519.40 g/mol, XLogP of 4.30, 9 rotatable bonds, 2 hydrogen bond donors, and 10 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[2-(2-amino-2-oxoethoxy)-4-fluorophenoxy]-4-cyclopropyl-N-(2-methoxy-4-pyridinyl)-5-(trifluoromethyl)benzamide is sourced from PubChem (CID 163361470), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).