2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide

C168H158N28O19 — CID 163641786

IUPAC2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.CC1CC1C(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.CN1CCN(CC(=O)Nc2cc(Oc3ccc4c(c3)CC(c3ncc(-c5ccccc5)[nH]3)CO4)ccn2)CC1.O=C(CC1CC1)c1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(CN1CC[C@@H](O)C1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(Cn1ccnc1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1
InChIInChI=1S/C30H32N6O3.C29H29N5O4.C28H24N6O3.C28H26N4O3.C28H25N3O3.C25H22N4O3/c1-35-11-13-36(14-12-35)19-29(37)34-28-17-25(9-10-31-28)39-24-7-8-27-22(16-24)15-23(20-38-27)30-32-18-26(33-30)21-5-3-2-4-6-21;35-22-9-11-34(16-22)17-28(36)33-27-14-24(8-10-30-27)38-23-6-7-26-20(13-23)12-21(18-37-26)29-31-15-25(32-29)19-4-2-1-3-5-19;35-27(16-34-11-10-29-18-34)33-26-14-23(8-9-30-26)37-22-6-7-25-20(13-22)12-21(17-36-25)28-31-15-24(32-28)19-4-2-1-3-5-19;1-17-11-23(17)28(33)32-26-14-22(9-10-29-26)35-21-7-8-25-19(13-21)12-20(16-34-25)27-30-15-24(31-27)18-5-3-2-4-6-18;32-26(12-18-6-7-18)24-15-23(10-11-29-24)34-22-8-9-27-20(14-22)13-21(17-33-27)28-30-16-25(31-28)19-4-2-1-3-5-19;1-16(30)28-24-13-21(9-10-26-24)32-20-7-8-23-18(12-20)11-19(15-31-23)25-27-14-22(29-25)17-5-3-2-4-6-17/h2-10,16-18,23H,11-15,19-20H2,1H3,(H,32,33)(H,31,34,37);1-8,10,13-15,21-22,35H,9,11-12,16-18H2,(H,31,32)(H,30,33,36);1-11,13-15,18,21H,12,16-17H2,(H,31,32)(H,30,33,35);2-10,13-15,17,20,23H,11-12,16H2,1H3,(H,30,31)(H,29,32,33);1-5,8-11,14-16,18,21H,6-7,12-13,17H2,(H,30,31);2-10,12-14,19H,11,15H2,1H3,(H,27,29)(H,26,28,30)/t;21?,22-;;;;/m.1..../s1
InChIKeyIEVYMUPAFFXDFW-ZJYFZXTRSA-N
MW2873.29 g/mol
LogP29.46
Rot. Bonds39

About 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide

2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide (PubChem CID 163641786) has the molecular formula C168H158N28O19 and a molecular weight of 2873.29 g/mol. Its IUPAC name is 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide.

Molecular Properties

Compound Name2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide
PubChem CID163641786
Molecular FormulaC168H158N28O19
Molecular Weight2873.29 g/mol
Exact Mass2871.23
IUPAC Name2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.CC1CC1C(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.CN1CCN(CC(=O)Nc2cc(Oc3ccc4c(c3)CC(c3ncc(-c5ccccc5)[nH]3)CO4)ccn2)CC1.O=C(CC1CC1)c1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(CN1CC[C@@H](O)C1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(Cn1ccnc1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1
InChIInChI=1S/C30H32N6O3.C29H29N5O4.C28H24N6O3.C28H26N4O3.C28H25N3O3.C25H22N4O3/c1-35-11-13-36(14-12-35)19-29(37)34-28-17-25(9-10-31-28)39-24-7-8-27-22(16-24)15-23(20-38-27)30-32-18-26(33-30)21-5-3-2-4-6-21;35-22-9-11-34(16-22)17-28(36)33-27-14-24(8-10-30-27)38-23-6-7-26-20(13-23)12-21(18-37-26)29-31-15-25(32-29)19-4-2-1-3-5-19;35-27(16-34-11-10-29-18-34)33-26-14-23(8-9-30-26)37-22-6-7-25-20(13-22)12-21(17-36-25)28-31-15-24(32-28)19-4-2-1-3-5-19;1-17-11-23(17)28(33)32-26-14-22(9-10-29-26)35-21-7-8-25-19(13-21)12-20(16-34-25)27-30-15-24(31-27)18-5-3-2-4-6-18;32-26(12-18-6-7-18)24-15-23(10-11-29-24)34-22-8-9-27-20(14-22)13-21(17-33-27)28-30-16-25(31-28)19-4-2-1-3-5-19;1-16(30)28-24-13-21(9-10-26-24)32-20-7-8-23-18(12-20)11-19(15-31-23)25-27-14-22(29-25)17-5-3-2-4-6-17/h2-10,16-18,23H,11-15,19-20H2,1H3,(H,32,33)(H,31,34,37);1-8,10,13-15,21-22,35H,9,11-12,16-18H2,(H,31,32)(H,30,33,36);1-11,13-15,18,21H,12,16-17H2,(H,31,32)(H,30,33,35);2-10,13-15,17,20,23H,11-12,16H2,1H3,(H,30,31)(H,29,32,33);1-5,8-11,14-16,18,21H,6-7,12-13,17H2,(H,30,31);2-10,12-14,19H,11,15H2,1H3,(H,27,29)(H,26,28,30)/t;21?,22-;;;;/m.1..../s1
InChIKeyIEVYMUPAFFXDFW-ZJYFZXTRSA-N
XLogP29.46
TPSA570.52 Ų
H-Bond Donors12
H-Bond Acceptors36
Rotatable Bonds39
Heavy Atoms215
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002873.29
LogP ≤ 529.46
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1036

Analyze 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide with MolForge

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Launch Full Analysis

Related Compounds

ethyl 5-[(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-4-yl)oxy]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-1-carboxylate;5-[[1-(hydroxymethyl)-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-4-yl)oxy]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-1-carbaldehyde;bis(5-[[1-[5-(trifluoromethyl)-1H-imidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one)
CID 161099206
5-[[1-(6-tert-butyl-1H-benzimidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[1-[1-methyl-5-(trifluoromethyl)benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[1-[1-methyl-6-(trifluoromethyl)benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-[5-[(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-4-yl)oxy]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-1-yl]-3H-benzimidazole-5-carboxamide;5-[[1-(3,5,6,7-tetrahydrocyclopenta[f]benzimidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
CID 161279595
2,2-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;1-fluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;bis(N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropanecarboxamide);N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-2-yl]cyclopropanecarboxamide
CID 163469682
5-[[3-[5-(2,4-dimethoxypyrimidin-5-yl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-[3-[(dimethylamino)methyl]-5-(trifluoromethyl)phenyl]-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-(3-methoxyphenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;bis(5-[[3-[5-(4-methylphenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one);5-[[3-[5-[3-(trifluoromethyl)phenyl]-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
CID 163523451
5-[[3-[5-(2-fluoro-5-methylphenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-(3-fluorophenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-(5-methoxy-3-pyridinyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-[3-(3-methylbutyl)-5-(trifluoromethyl)phenyl]-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-(2-methylphenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;5-[[3-[5-(3-methylphenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
CID 163652781
3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide
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[3-[cyclohexylmethoxy-(3-methylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[3-[3-(cyclohexylmethoxy)phenyl]-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;cyclohexyl-[4-[3-[2-methyl-6-(piperidine-1-carbonyl)imidazo[1,2-a]pyridin-3-yl]phenyl]piperazin-1-yl]methanone;[3-[hydroxy-(3-methylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[2-methyl-3-(3-methylbenzoyl)imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[2-methyl-3-[1-(3-methylphenyl)ethyl]imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;N-(2-methyl-3-phenylimidazo[1,2-a]pyridin-6-yl)oxane-4-carboxamide
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N-(cyclopropylmethyl)-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;N-cyclopropyl-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;N-(2-hydroxyethyl)-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;N-(2-methoxyethyl)-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-N-pyridin-3-ylbenzamide
CID 157338888
1-[3-[4-[cyclopropyl-[(3R)-oxolan-3-yl]amino]-6-piperidin-1-ylpyrimidin-2-yl]phenoxy]-3-(methylamino)propan-2-ol;1-[3-[4-(6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl)-5-methyl-6-[[(3R)-oxolan-3-yl]methyl]pyrimidin-2-yl]phenoxy]-3-(methylamino)propan-2-ol;2-[3-[2-hydroxy-3-(methylamino)propoxy]phenyl]-N,5-dimethyl-N-(oxan-4-ylmethyl)-6-[[(3R)-oxolan-3-yl]methyl]pyrimidine-4-carboxamide;1-[2-[3-[2-hydroxy-3-(methylamino)propoxy]phenyl]-5-methyl-6-[[(3R)-oxolan-3-yl]methyl]pyrimidin-4-yl]piperidin-4-ol;(3R)-1-[2-[3-[2-hydroxy-3-(methylamino)propoxy]phenyl]-5-methyl-6-[[(3R)-oxolan-3-yl]methyl]pyrimidin-4-yl]piperidin-3-ol
CID 158049923
[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-(3,5-dimethoxyphenyl)methanone;tris([4-[1-(cyclopropylmethyl)benzimidazol-2-yl]piperidin-1-yl]-(3,5-dimethoxyphenyl)methanone);(3,5-dimethoxyphenyl)-[4-[1-[(3-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-1-yl]methanone;(3,5-dimethoxyphenyl)-[4-[1-(oxan-4-ylmethyl)benzimidazol-2-yl]piperidin-1-yl]methanone;(3,5-dimethoxyphenyl)-[4-[1-(oxolan-2-ylmethyl)benzimidazol-2-yl]piperidin-1-yl]methanone;(3,5-dimethoxyphenyl)-[4-[1-(pyridin-4-ylmethyl)benzimidazol-2-yl]piperidin-1-yl]methanone;2-[1-[[4-(4-fluorophenoxy)phenyl]methyl]piperidin-4-yl]-1H-benzimidazole;2-[1-[[4-(4-methoxyphenoxy)phenyl]methyl]piperidin-4-yl]-1H-benzimidazole;2-[1-[(4-phenylmethoxyphenyl)methyl]piperidin-4-yl]-1H-benzimidazole
CID 158252738
N-(2-hydroxy-3-propan-2-yloxypropyl)-N-[[4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]naphthalen-1-yl]methyl]acetamide;N-(3-hydroxy-2-propan-2-yloxypropyl)-N-[[4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]naphthalen-1-yl]methyl]acetamide;N-[(3-propan-2-yloxycyclobutyl)methyl]-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;N-(2-propan-2-yloxyethyl)-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;6-[(2R)-2-[[4-[[(2R)-2-(propan-2-yloxymethyl)pyrrolidin-1-yl]methyl]naphthalen-1-yl]oxymethyl]pyrrolidin-1-yl]-7H-purine;6-[(2R)-2-[(7-propan-2-yloxynaphthalen-1-yl)oxymethyl]pyrrolidin-1-yl]-7H-purine;N-(3-propan-2-yloxypropyl)-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;(E)-7-propan-2-yloxy-1-[2-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]phenyl]hept-1-en-3-one
CID 158423733
N-(2-hydroxy-3-propan-2-yloxypropyl)-N-[[4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]naphthalen-1-yl]methyl]acetamide;6-[(2R,4R)-2-(naphthalen-1-yloxymethyl)-4-propan-2-yloxypyrrolidin-1-yl]-7H-purine;N-[(3-propan-2-yloxycyclobutyl)methyl]-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;N-(2-propan-2-yloxyethyl)-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;2-(propan-2-yloxymethylidene)-5-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]-3,4-dihydronaphthalen-1-one;N-(2-propan-2-yloxypropyl)-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;N-(3-propan-2-yloxypropyl)-4-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]quinoline-2-carboxamide;(E)-7-propan-2-yloxy-1-[2-[[(2R)-1-(7H-purin-6-yl)pyrrolidin-2-yl]methoxy]phenyl]hept-1-en-3-one
CID 158630343

Frequently Asked Questions

What is the IUPAC name of 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide?
The IUPAC name of 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide (CID 163641786) is 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide.
What is the SMILES notation for 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide?
The canonical SMILES for 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide is CC(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.CC1CC1C(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.CN1CCN(CC(=O)Nc2cc(Oc3ccc4c(c3)CC(c3ncc(-c5ccccc5)[nH]3)CO4)ccn2)CC1.O=C(CC1CC1)c1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(CN1CC[C@@H](O)C1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(Cn1ccnc1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.
What is the InChIKey of 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide?
The InChIKey is IEVYMUPAFFXDFW-ZJYFZXTRSA-N. The full InChI is InChI=1S/C30H32N6O3.C29H29N5O4.C28H24N6O3.C28H26N4O3.C28H25N3O3.C25H22N4O3/c1-35-11-13-36(14-12-35)19-29(37)34-28-17-25(9-10-31-28)39-24-7-8-27-22(16-24)15-23(20-38-27)30-32-18-26(33-30)21-5-3-2-4-6-21;35-22-9-11-34(16-22)17-28(36)33-27-14-24(8-10-30-27)38-23-6-7-26-20(13-23)12-21(18-37-26)29-31-15-25(32-29)19-4-2-1-3-5-19;35-27(16-34-11-10-29-18-34)33-26-14-23(8-9-30-26)37-22-6-7-25-20(13-22)12-21(17-36-25)28-31-15-24(32-28)19-4-2-1-3-5-19;1-17-11-23(17)28(33)32-26-14-22(9-10-29-26)35-21-7-8-25-19(13-21)12-20(16-34-25)27-30-15-24(31-27)18-5-3-2-4-6-18;32-26(12-18-6-7-18)24-15-23(10-11-29-24)34-22-8-9-27-20(14-22)13-21(17-33-27)28-30-16-25(31-28)19-4-2-1-3-5-19;1-16(30)28-24-13-21(9-10-26-24)32-20-7-8-23-18(12-20)11-19(15-31-23)25-27-14-22(29-25)17-5-3-2-4-6-17/h2-10,16-18,23H,11-15,19-20H2,1H3,(H,32,33)(H,31,34,37);1-8,10,13-15,21-22,35H,9,11-12,16-18H2,(H,31,32)(H,30,33,36);1-11,13-15,18,21H,12,16-17H2,(H,31,32)(H,30,33,35);2-10,13-15,17,20,23H,11-12,16H2,1H3,(H,30,31)(H,29,32,33);1-5,8-11,14-16,18,21H,6-7,12-13,17H2,(H,30,31);2-10,12-14,19H,11,15H2,1H3,(H,27,29)(H,26,28,30)/t;21?,22-;;;;/m.1..../s1.
What are the key properties of 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide?
2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide has a molecular weight of 2873.29 g/mol, XLogP of 29.46, 39 rotatable bonds, 12 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for 2-cyclopropyl-1-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]ethanone;2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-imidazol-1-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;2-methyl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclopropane-1-carboxamide;2-(4-methylpiperazin-1-yl)-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]acetamide is sourced from PubChem (CID 163641786), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).