3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide

C141H130F2N24O15 — CID 163909339

About 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide

3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide (PubChem CID 163909339) has the molecular formula C141H130F2N24O15 and a molecular weight of 2438.74 g/mol. Its IUPAC name is 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide.

Molecular Properties

• Compound Name: 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide
• PubChem CID: 163909339
• Molecular Formula: C141H130F2N24O15
• Molecular Weight: 2438.74 g/mol
• Exact Mass: 2437.01
• IUPAC Name: 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide
• SMILES: CC(C(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1)N1CCOCC1.O=C(CN1CCCC1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1)C1CC(F)(F)C1.O=C(Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ncn1)C1CC1.c1ccc(-c2cnc(C3COc4ccc(Oc5ccnc(Nc6ccccn6)c5)cc4C3)[nH]2)cc1
• InChI: InChI=1S/C30H31N5O4.C29H29N5O3.C28H24F2N4O3.C28H23N5O2.C26H23N5O3/c1-20(35-11-13-37-14-12-35)30(36)34-28-17-25(9-10-31-28)39-24-7-8-27-22(16-24)15-23(19-38-27)29-32-18-26(33-29)21-5-3-2-4-6-21;35-28(18-34-12-4-5-13-34)33-27-16-24(10-11-30-27)37-23-8-9-26-21(15-23)14-22(19-36-26)29-31-17-25(32-29)20-6-2-1-3-7-20;29-28(30)13-20(14-28)27(35)34-25-12-22(8-9-31-25)37-21-6-7-24-18(11-21)10-19(16-36-24)26-32-15-23(33-26)17-4-2-1-3-5-17;1-2-6-19(7-3-1)24-17-31-28(32-24)21-14-20-15-22(9-10-25(20)34-18-21)35-23-11-13-30-27(16-23)33-26-8-4-5-12-29-26;32-26(17-6-7-17)31-23-12-24(29-15-28-23)34-20-8-9-22-18(11-20)10-19(14-33-22)25-27-13-21(30-25)16-4-2-1-3-5-16/h2-10,16-18,20,23H,11-15,19H2,1H3,(H,32,33)(H,31,34,36);1-3,6-11,15-17,22H,4-5,12-14,18-19H2,(H,31,32)(H,30,33,35);1-9,11-12,15,19-20H,10,13-14,16H2,(H,32,33)(H,31,34,35);1-13,15-17,21H,14,18H2,(H,31,32)(H,29,30,33);1-5,8-9,11-13,15,17,19H,6-7,10,14H2,(H,27,30)(H,28,29,31,32)
• InChIKey: QQSWKMWJPFCAMD-UHFFFAOYSA-N
• XLogP: 26.47
• TPSA: 470.07 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 30
• Rotatable Bonds: 32
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2438.74
LogP ≤ 5	26.47
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide?

The IUPAC name of 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide (CID 163909339) is 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide.

What is the SMILES notation for 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide?

The canonical SMILES for 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide is CC(C(=O)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1)N1CCOCC1.O=C(CN1CCCC1)Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1.O=C(Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ccn1)C1CC(F)(F)C1.O=C(Nc1cc(Oc2ccc3c(c2)CC(c2ncc(-c4ccccc4)[nH]2)CO3)ncn1)C1CC1.c1ccc(-c2cnc(C3COc4ccc(Oc5ccnc(Nc6ccccn6)c5)cc4C3)[nH]2)cc1.

What is the InChIKey of 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide?

The InChIKey is QQSWKMWJPFCAMD-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H31N5O4.C29H29N5O3.C28H24F2N4O3.C28H23N5O2.C26H23N5O3/c1-20(35-11-13-37-14-12-35)30(36)34-28-17-25(9-10-31-28)39-24-7-8-27-22(16-24)15-23(19-38-27)29-32-18-26(33-29)21-5-3-2-4-6-21;35-28(18-34-12-4-5-13-34)33-27-16-24(10-11-30-27)37-23-8-9-26-21(15-23)14-22(19-36-26)29-31-17-25(32-29)20-6-2-1-3-7-20;29-28(30)13-20(14-28)27(35)34-25-12-22(8-9-31-25)37-21-6-7-24-18(11-21)10-19(16-36-24)26-32-15-23(33-26)17-4-2-1-3-5-17;1-2-6-19(7-3-1)24-17-31-28(32-24)21-14-20-15-22(9-10-25(20)34-18-21)35-23-11-13-30-27(16-23)33-26-8-4-5-12-29-26;32-26(17-6-7-17)31-23-12-24(29-15-28-23)34-20-8-9-22-18(11-20)10-19(14-33-22)25-27-13-21(30-25)16-4-2-1-3-5-16/h2-10,16-18,20,23H,11-15,19H2,1H3,(H,32,33)(H,31,34,36);1-3,6-11,15-17,22H,4-5,12-14,18-19H2,(H,31,32)(H,30,33,35);1-9,11-12,15,19-20H,10,13-14,16H2,(H,32,33)(H,31,34,35);1-13,15-17,21H,14,18H2,(H,31,32)(H,29,30,33);1-5,8-9,11-13,15,17,19H,6-7,10,14H2,(H,27,30)(H,28,29,31,32).

What are the key properties of 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide?

3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide has a molecular weight of 2438.74 g/mol, XLogP of 26.47, 32 rotatable bonds, 10 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 3,3-difluoro-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]cyclobutane-1-carboxamide;2-morpholin-4-yl-N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]propanamide;4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-N-pyridin-2-ylpyridin-2-amine;N-[4-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]-2-pyridinyl]-2-pyrrolidin-1-ylacetamide;N-[6-[[3-(5-phenyl-1H-imidazol-2-yl)-3,4-dihydro-2H-chromen-6-yl]oxy]pyrimidin-4-yl]cyclopropanecarboxamide is sourced from PubChem (CID 163909339), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).