N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C128H135F21N36O14 — CID 163709947

IUPACN-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)no1.Cc1cc(N2CCC(C)(C)C2=O)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(N2CCN(C(C)C)C2=O)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1conc1-c1cc(C)n2ncc(C(=O)N[C@H](C3CC3)C(F)(F)F)c2n1.Cc1nc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)c(C)o1.Cc1nc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)oc1C.Cc1oc(C(C)C)nc1-c1cc(C)n2ncc(C(=O)N[C@H](C3CC3)C(F)(F)F)c2n1
InChIInChI=1S/C20H22F3N5O2.C19H23F3N6O2.C19H22F3N5O2.2C18H18F3N5O2.2C17H16F3N5O2/c1-9(2)19-26-15(11(4)30-19)14-7-10(3)28-17(25-14)13(8-24-28)18(29)27-16(12-5-6-12)20(21,22)23;1-10(2)26-6-7-27(18(26)30)14-8-11(3)28-16(24-14)13(9-23-28)17(29)25-15(12-4-5-12)19(20,21)22;1-10-8-13(26-7-6-18(2,3)17(26)29)24-15-12(9-23-27(10)15)16(28)25-14(11-4-5-11)19(20,21)22;1-8-6-13(14-9(2)28-10(3)23-14)24-16-12(7-22-26(8)16)17(27)25-15(11-4-5-11)18(19,20)21;1-8-6-13(17-23-9(2)10(3)28-17)24-15-12(7-22-26(8)15)16(27)25-14(11-4-5-11)18(19,20)21;1-8-7-27-24-13(8)12-5-9(2)25-15(22-12)11(6-21-25)16(26)23-14(10-3-4-10)17(18,19)20;1-8-5-12(13-6-9(2)27-24-13)22-15-11(7-21-25(8)15)16(26)23-14(10-3-4-10)17(18,19)20/h7-9,12,16H,5-6H2,1-4H3,(H,27,29);8-10,12,15H,4-7H2,1-3H3,(H,25,29);8-9,11,14H,4-7H2,1-3H3,(H,25,28);6-7,11,15H,4-5H2,1-3H3,(H,25,27);6-7,11,14H,4-5H2,1-3H3,(H,25,27);2*5-7,10,14H,3-4H2,1-2H3,(H,23,26)/t16-;15-;;15-;3*14-/m11.1111/s1
InChIKeyKIIJCCLPPUQIJD-IWCWWAMXSA-N
MW2800.68 g/mol
LogP22.73
Rot. Bonds30

About N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 163709947) has the molecular formula C128H135F21N36O14 and a molecular weight of 2800.68 g/mol. Its IUPAC name is N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound NameN-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID163709947
Molecular FormulaC128H135F21N36O14
Molecular Weight2800.68 g/mol
Exact Mass2799.06
IUPAC NameN-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)no1.Cc1cc(N2CCC(C)(C)C2=O)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(N2CCN(C(C)C)C2=O)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1conc1-c1cc(C)n2ncc(C(=O)N[C@H](C3CC3)C(F)(F)F)c2n1.Cc1nc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)c(C)o1.Cc1nc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)oc1C.Cc1oc(C(C)C)nc1-c1cc(C)n2ncc(C(=O)N[C@H](C3CC3)C(F)(F)F)c2n1
InChIInChI=1S/C20H22F3N5O2.C19H23F3N6O2.C19H22F3N5O2.2C18H18F3N5O2.2C17H16F3N5O2/c1-9(2)19-26-15(11(4)30-19)14-7-10(3)28-17(25-14)13(8-24-28)18(29)27-16(12-5-6-12)20(21,22)23;1-10(2)26-6-7-27(18(26)30)14-8-11(3)28-16(24-14)13(9-23-28)17(29)25-15(12-4-5-12)19(20,21)22;1-10-8-13(26-7-6-18(2,3)17(26)29)24-15-12(9-23-27(10)15)16(28)25-14(11-4-5-11)19(20,21)22;1-8-6-13(14-9(2)28-10(3)23-14)24-16-12(7-22-26(8)16)17(27)25-15(11-4-5-11)18(19,20)21;1-8-6-13(17-23-9(2)10(3)28-17)24-15-12(7-22-26(8)15)16(27)25-14(11-4-5-11)18(19,20)21;1-8-7-27-24-13(8)12-5-9(2)25-15(22-12)11(6-21-25)16(26)23-14(10-3-4-10)17(18,19)20;1-8-5-12(13-6-9(2)27-24-13)22-15-11(7-21-25(8)15)16(26)23-14(10-3-4-10)17(18,19)20/h7-9,12,16H,5-6H2,1-4H3,(H,27,29);8-10,12,15H,4-7H2,1-3H3,(H,25,29);8-9,11,14H,4-7H2,1-3H3,(H,25,28);6-7,11,15H,4-5H2,1-3H3,(H,25,27);6-7,11,14H,4-5H2,1-3H3,(H,25,27);2*5-7,10,14H,3-4H2,1-2H3,(H,23,26)/t16-;15-;;15-;3*14-/m11.1111/s1
InChIKeyKIIJCCLPPUQIJD-IWCWWAMXSA-N
XLogP22.73
TPSA589.04 Ų
H-Bond Donors7
H-Bond Acceptors40
Rotatable Bonds30
Heavy Atoms199
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002800.68
LogP ≤ 522.73
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1040

Analyze N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

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3-{1-[5-(Furan-2-YL)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carbonyl]pyrrolidin-2-YL}-5-(propan-2-YL)-1,2-oxazole
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3-{1-[5-(Furan-2-YL)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carbonyl]pyrrolidin-2-YL}-5-propyl-1,2-oxazole
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CID 156119802
tert-butyl 2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]-8-oxo-9H-purine-7-carboxylate;2,2-difluoro-N-[2-[1-[(2-fluorophenyl)methyl]-5-(1,3-oxazol-2-yl)pyrazol-3-yl]-6-oxo-1H-pyrimidin-5-yl]-1-methylcyclopropane-1-carboxamide
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5-[4-(difluoromethoxy)phenyl]-3-(2-oxo-2-pyrrolidin-1-ylethyl)-1,3-benzoxazol-2-one;3-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-2-methylidene-5-[4-(trifluoromethoxy)phenyl]-[1,3]oxazolo[4,5-b]pyridine;3-[(2-methylfuran-3-yl)methyl]-5-[4-(trifluoromethoxy)phenyl]-[1,3]oxazolo[4,5-b]pyridin-2-one;3-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-5-[4-(trifluoromethoxy)phenyl]-[1,3]oxazolo[4,5-b]pyridin-2-one;3-[(1-methylpyrazol-4-yl)methyl]-5-[4-(trifluoromethoxy)phenyl]-[1,3]oxazolo[4,5-b]pyridin-2-one;3-[(2R)-2-pyrimidin-2-ylpropyl]-5-[4-(trifluoromethoxy)phenyl]-[1,3]oxazolo[4,5-b]pyridin-2-one;3-[(2S)-2-pyrimidin-2-ylpropyl]-5-[4-(trifluoromethoxy)phenyl]-[1,3]oxazolo[4,5-b]pyridin-2-one
CID 159736067
acetic acid;N-cyclohexyl-1-methyl-6-(3-piperazin-1-ylpropoxy)pyrazolo[5,4-b]pyridine-3-carboxamide;N-cyclohexyl-1-methyl-6-(pyridin-2-ylmethoxy)pyrazolo[5,4-b]pyridine-3-carboxamide;N-(1-methyl-6-pentan-3-yloxypyrazolo[5,4-b]pyridin-3-yl)cyclohexanecarboxamide;N-(1-methyl-6-pentan-3-yloxypyrazolo[5,4-b]pyridin-3-yl)pyridine-3-carboxamide;heptakis(2,2,2-trifluoroacetic acid)
CID 159918219

Frequently Asked Questions

What is the IUPAC name of N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 163709947) is N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is Cc1cc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)no1.Cc1cc(N2CCC(C)(C)C2=O)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(N2CCN(C(C)C)C2=O)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1conc1-c1cc(C)n2ncc(C(=O)N[C@H](C3CC3)C(F)(F)F)c2n1.Cc1nc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)c(C)o1.Cc1nc(-c2cc(C)n3ncc(C(=O)N[C@H](C4CC4)C(F)(F)F)c3n2)oc1C.Cc1oc(C(C)C)nc1-c1cc(C)n2ncc(C(=O)N[C@H](C3CC3)C(F)(F)F)c2n1.
What is the InChIKey of N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is KIIJCCLPPUQIJD-IWCWWAMXSA-N. The full InChI is InChI=1S/C20H22F3N5O2.C19H23F3N6O2.C19H22F3N5O2.2C18H18F3N5O2.2C17H16F3N5O2/c1-9(2)19-26-15(11(4)30-19)14-7-10(3)28-17(25-14)13(8-24-28)18(29)27-16(12-5-6-12)20(21,22)23;1-10(2)26-6-7-27(18(26)30)14-8-11(3)28-16(24-14)13(9-23-28)17(29)25-15(12-4-5-12)19(20,21)22;1-10-8-13(26-7-6-18(2,3)17(26)29)24-15-12(9-23-27(10)15)16(28)25-14(11-4-5-11)19(20,21)22;1-8-6-13(14-9(2)28-10(3)23-14)24-16-12(7-22-26(8)16)17(27)25-15(11-4-5-11)18(19,20)21;1-8-6-13(17-23-9(2)10(3)28-17)24-15-12(7-22-26(8)15)16(27)25-14(11-4-5-11)18(19,20)21;1-8-7-27-24-13(8)12-5-9(2)25-15(22-12)11(6-21-25)16(26)23-14(10-3-4-10)17(18,19)20;1-8-5-12(13-6-9(2)27-24-13)22-15-11(7-21-25(8)15)16(26)23-14(10-3-4-10)17(18,19)20/h7-9,12,16H,5-6H2,1-4H3,(H,27,29);8-10,12,15H,4-7H2,1-3H3,(H,25,29);8-9,11,14H,4-7H2,1-3H3,(H,25,28);6-7,11,15H,4-5H2,1-3H3,(H,25,27);6-7,11,14H,4-5H2,1-3H3,(H,25,27);2*5-7,10,14H,3-4H2,1-2H3,(H,23,26)/t16-;15-;;15-;3*14-/m11.1111/s1.
What are the key properties of N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2800.68 g/mol, XLogP of 22.73, 30 rotatable bonds, 7 hydrogen bond donors, and 40 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 163709947), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).