2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide

C105H116ClF5N30O8 — CID 158191746

IUPAC2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCc1cc(-c2cc(Cl)c(F)cn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C(C)C)ncn12.Cc1cc(-c2ccn(C)n2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccon2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2cocn2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(NC2CC2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12
InChIInChI=1S/C19H21FN4O.C18H17ClFN5O.C18H22N6O.2C17H19N5O2.C16H18F3N5O/c1-11(2)13(4)22-19(25)17-18-23-16(9-12(3)24(18)10-21-17)14-5-7-15(20)8-6-14;1-9-5-15(14-6-12(19)13(20)7-21-14)24-17-16(22-8-25(9)17)18(26)23-10(2)11-3-4-11;1-11-9-14(13-7-8-23(4)22-13)20-16-15(19-10-24(11)16)17(25)21-18(2,3)12-5-6-12;1-10-6-12(13-7-24-9-19-13)20-15-14(18-8-22(10)15)16(23)21-17(2,3)11-4-5-11;1-10-8-13(12-6-7-24-21-12)19-15-14(18-9-22(10)15)16(23)20-17(2,3)11-4-5-11;1-8-6-11(21-10-4-5-10)22-14-12(20-7-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h5-11,13H,1-4H3,(H,22,25);5-8,10-11H,3-4H2,1-2H3,(H,23,26);7-10,12H,5-6H2,1-4H3,(H,21,25);6-9,11H,4-5H2,1-3H3,(H,21,23);6-9,11H,4-5H2,1-3H3,(H,20,23);6-7,9-10,13H,2-5H2,1H3,(H,21,22)(H,23,25)/t13-;10-;;;;/m00..../s1
InChIKeyFZVNWTGRSLUJCG-XENNIITESA-N
MW2056.73 g/mol
LogP17.30
Rot. Bonds25

About 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide

2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 158191746) has the molecular formula C105H116ClF5N30O8 and a molecular weight of 2056.73 g/mol. Its IUPAC name is 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound Name2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
PubChem CID158191746
Molecular FormulaC105H116ClF5N30O8
Molecular Weight2056.73 g/mol
Exact Mass2054.92
IUPAC Name2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCc1cc(-c2cc(Cl)c(F)cn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C(C)C)ncn12.Cc1cc(-c2ccn(C)n2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccon2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2cocn2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(NC2CC2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12
InChIInChI=1S/C19H21FN4O.C18H17ClFN5O.C18H22N6O.2C17H19N5O2.C16H18F3N5O/c1-11(2)13(4)22-19(25)17-18-23-16(9-12(3)24(18)10-21-17)14-5-7-15(20)8-6-14;1-9-5-15(14-6-12(19)13(20)7-21-14)24-17-16(22-8-25(9)17)18(26)23-10(2)11-3-4-11;1-11-9-14(13-7-8-23(4)22-13)20-16-15(19-10-24(11)16)17(25)21-18(2,3)12-5-6-12;1-10-6-12(13-7-24-9-19-13)20-15-14(18-8-22(10)15)16(23)21-17(2,3)11-4-5-11;1-10-8-13(12-6-7-24-21-12)19-15-14(18-9-22(10)15)16(23)20-17(2,3)11-4-5-11;1-8-6-11(21-10-4-5-10)22-14-12(20-7-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h5-11,13H,1-4H3,(H,22,25);5-8,10-11H,3-4H2,1-2H3,(H,23,26);7-10,12H,5-6H2,1-4H3,(H,21,25);6-9,11H,4-5H2,1-3H3,(H,21,23);6-9,11H,4-5H2,1-3H3,(H,20,23);6-7,9-10,13H,2-5H2,1H3,(H,21,22)(H,23,25)/t13-;10-;;;;/m00..../s1
InChIKeyFZVNWTGRSLUJCG-XENNIITESA-N
XLogP17.30
TPSA450.54 Ų
H-Bond Donors7
H-Bond Acceptors32
Rotatable Bonds25
Heavy Atoms149
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002056.73
LogP ≤ 517.30
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1032

Analyze 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-chloro-2-propan-2-ylimidazo[1,2-b]pyridazine;6-cyclopropyl-2-propan-2-ylimidazo[1,2-b]pyridazine;6-fluoro-2-propan-2-ylimidazo[1,2-b]pyridazine;6-imidazol-1-yl-2-propan-2-ylimidazo[1,2-b]pyridazine;6-methoxy-2-propan-2-ylimidazo[1,2-b]pyridazine;6-methyl-2-propan-2-ylimidazo[1,2-b]pyridazine;2-propan-2-yl-3a,7a-dihydro-1H-pyrrolo[2,3-c]pyridine;2-propan-2-yl-3a,7a-dihydro-1H-pyrrolo[3,2-c]pyridine;3-propan-2-yl-2,1-benzoxazole;bis(2-propan-2-ylimidazo[1,2-b]pyridazine);4-(2-propan-2-ylimidazo[1,2-b]pyridazin-6-yl)morpholine;2-propan-2-yl-6-pyrrolidin-1-ylimidazo[1,2-b]pyridazine;2-propan-2-yl-6-(trifluoromethyl)imidazo[1,2-b]pyridazine
CID 157458205
(1R,5S)-N-[2-(1,2-benzoxazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(1-benzylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(1-chloroisoquinolin-4-yl)oxy-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-[(2-methyl-3-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-[4-(trifluoromethyl)pyridazin-3-yl]oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-[[3-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 157987542
CID 161348184
CID 161348184
benzyl 3-[3-cyclopropyl-7-(pyridine-3-carbonylamino)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate;benzyl 4-[3-cyclopropyl-7-(pyridine-3-carbonylamino)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-ethynyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 161713726
2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
CID 162038625
5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163413630
N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(5-isocyano-2-methylfuran-3-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(5-isocyano-2-methylfuran-3-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3-isocyano-5-methylfuran-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(5-isocyano-2-methylfuran-3-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-methyl-1,3-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163670881
N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163709947
5-(1,3-benzoxazol-5-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(6-chloro-2-pyridinyl)-N-(2-cyclopropylpropan-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-difluoropiperidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(2-fluoro-3-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-fluoro-3-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-pyridin-3-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163817943
5-(1,3-benzoxazol-4-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzoxazol-5-yl)-N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzoxazol-5-yl)-N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzoxazol-5-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-fluoro-3-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163908540
N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(5-fluorofuran-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(4-methoxy-3-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(4-methyl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(5-methyl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(6-methyl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 164062535
N-(2-cyclopropylpropan-2-yl)-7-methyl-5-(2-methyl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2-cyclopropylpropan-2-yl)-7-methyl-5-(2-methyl-1,3-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3-isocyanofuran-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-methyl-1,3-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-methyl-1,3-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-methyl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(5-methyl-1,3-oxazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 164088229

Frequently Asked Questions

What is the IUPAC name of 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide?
The IUPAC name of 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide (CID 158191746) is 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide.
What is the SMILES notation for 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide?
The canonical SMILES for 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide is Cc1cc(-c2cc(Cl)c(F)cn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2ccc(F)cc2)nc2c(C(=O)N[C@@H](C)C(C)C)ncn12.Cc1cc(-c2ccn(C)n2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccon2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2cocn2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(NC2CC2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.
What is the InChIKey of 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide?
The InChIKey is FZVNWTGRSLUJCG-XENNIITESA-N. The full InChI is InChI=1S/C19H21FN4O.C18H17ClFN5O.C18H22N6O.2C17H19N5O2.C16H18F3N5O/c1-11(2)13(4)22-19(25)17-18-23-16(9-12(3)24(18)10-21-17)14-5-7-15(20)8-6-14;1-9-5-15(14-6-12(19)13(20)7-21-14)24-17-16(22-8-25(9)17)18(26)23-10(2)11-3-4-11;1-11-9-14(13-7-8-23(4)22-13)20-16-15(19-10-24(11)16)17(25)21-18(2,3)12-5-6-12;1-10-6-12(13-7-24-9-19-13)20-15-14(18-8-22(10)15)16(23)21-17(2,3)11-4-5-11;1-10-8-13(12-6-7-24-21-12)19-15-14(18-9-22(10)15)16(23)20-17(2,3)11-4-5-11;1-8-6-11(21-10-4-5-10)22-14-12(20-7-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h5-11,13H,1-4H3,(H,22,25);5-8,10-11H,3-4H2,1-2H3,(H,23,26);7-10,12H,5-6H2,1-4H3,(H,21,25);6-9,11H,4-5H2,1-3H3,(H,21,23);6-9,11H,4-5H2,1-3H3,(H,20,23);6-7,9-10,13H,2-5H2,1H3,(H,21,22)(H,23,25)/t13-;10-;;;;/m00..../s1.
What are the key properties of 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide?
2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2056.73 g/mol, XLogP of 17.30, 25 rotatable bonds, 7 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 158191746), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).