2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide

C83H65ClF3N11O4 — CID 163863897

IUPAC2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
SMILESCc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(C)nc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(CO)nc34)ccc2Cl)cc1
InChIInChI=1S/C28H21F3N4O.C28H23N3O.C27H21ClN4O2/c1-17-7-10-21(11-8-17)34-27(36)23-15-19(9-12-24(23)28(29,30)31)22-6-4-14-35-25(18(2)33-26(22)35)20-5-3-13-32-16-20;1-19-10-14-23(15-11-19)30-28(32)25-17-22(13-12-20(25)2)24-9-6-16-31-26(18-29-27(24)31)21-7-4-3-5-8-21;1-17-6-9-20(10-7-17)30-27(34)22-14-18(8-11-23(22)28)21-5-3-13-32-25(19-4-2-12-29-15-19)24(16-33)31-26(21)32/h3-16H,1-2H3,(H,34,36);3-18H,1-2H3,(H,30,32);2-15,33H,16H2,1H3,(H,30,34)
InChIKeyPEXUSWFQDJPZQY-UHFFFAOYSA-N
MW1372.95 g/mol
LogP19.26
Rot. Bonds13

About 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide

2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide (PubChem CID 163863897) has the molecular formula C83H65ClF3N11O4 and a molecular weight of 1372.95 g/mol. Its IUPAC name is 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide.

Molecular Properties

Compound Name2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
PubChem CID163863897
Molecular FormulaC83H65ClF3N11O4
Molecular Weight1372.95 g/mol
Exact Mass1371.49
IUPAC Name2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
SMILESCc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(C)nc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(CO)nc34)ccc2Cl)cc1
InChIInChI=1S/C28H21F3N4O.C28H23N3O.C27H21ClN4O2/c1-17-7-10-21(11-8-17)34-27(36)23-15-19(9-12-24(23)28(29,30)31)22-6-4-14-35-25(18(2)33-26(22)35)20-5-3-13-32-16-20;1-19-10-14-23(15-11-19)30-28(32)25-17-22(13-12-20(25)2)24-9-6-16-31-26(18-29-27(24)31)21-7-4-3-5-8-21;1-17-6-9-20(10-7-17)30-27(34)22-14-18(8-11-23(22)28)21-5-3-13-32-25(19-4-2-12-29-15-19)24(16-33)31-26(21)32/h3-16H,1-2H3,(H,34,36);3-18H,1-2H3,(H,30,32);2-15,33H,16H2,1H3,(H,30,34)
InChIKeyPEXUSWFQDJPZQY-UHFFFAOYSA-N
XLogP19.26
TPSA185.21 Ų
H-Bond Donors4
H-Bond Acceptors12
Rotatable Bonds13
Heavy Atoms102
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001372.95
LogP ≤ 519.26
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1012

Analyze 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide with MolForge

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Related Compounds

US11186579, Example 15
CID 146307450
5-[3-(2,3-difluorophenyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;5-[3-(5-fluoro-3-pyridinyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane
CID 157910930
2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
CID 158348744
5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
CID 158427544
5-[3-(2,3-difluorophenyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;5-[3-(5-fluoro-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide
CID 158721288
5-[3-(2-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;5-[3-(2-fluoro-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
CID 158976717
5-[3-(2,3-difluorophenyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(5-fluoro-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide
CID 159028582
2-[4-[[6-[3,5-bis(trifluoromethyl)phenyl]imidazo[1,2-a]pyrazin-8-yl]amino]-N-ethylanilino]ethanol;6-(2-chlorophenyl)-N-(pyridin-2-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;N-[4-[(6-naphthalen-2-ylimidazo[1,2-a]pyrazin-8-yl)amino]phenyl]acetamide;4-[8-(4-pyridin-2-ylpiperazin-1-yl)imidazo[1,2-a]pyrazin-6-yl]benzoic acid
CID 159239632
6-[2-(6-Chloro-2-fluoro-3-methylphenyl)ethyl]imidazo[1,2-a]pyridine-5-carboxylic acid;6-[2-(2-chloro-4-methylphenyl)ethyl]imidazo[1,2-a]pyridine-5-carboxylic acid;bis(6-[2-(2-fluoro-4-methylphenyl)ethyl]imidazo[1,2-a]pyridine-5-carboxylic acid);6-[2-(3-fluoro-5-methylphenyl)ethyl]imidazo[1,2-a]pyridine-5-carboxylic acid;6-[2-[5-methyl-2-(trifluoromethyl)phenyl]ethyl]imidazo[1,2-a]pyridine-5-carboxylic acid
CID 159553517
5-[3-(2,3-difluorophenyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;5-[3-(5-fluoro-3-pyridinyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide
CID 159757073
5-[3-(2,3-difluorophenyl)-3aH-pyrazolo[1,5-a]pyridin-8-ium-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(5-fluoro-3-pyridinyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide
CID 159838766
5-[3-(2,3-difluorophenyl)-2-(hydroxymethyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[1-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-5-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide
CID 160517791

Frequently Asked Questions

What is the IUPAC name of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?
The IUPAC name of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide (CID 163863897) is 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide.
What is the SMILES notation for 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?
The canonical SMILES for 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide is Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(C)nc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(CO)nc34)ccc2Cl)cc1.
What is the InChIKey of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?
The InChIKey is PEXUSWFQDJPZQY-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H21F3N4O.C28H23N3O.C27H21ClN4O2/c1-17-7-10-21(11-8-17)34-27(36)23-15-19(9-12-24(23)28(29,30)31)22-6-4-14-35-25(18(2)33-26(22)35)20-5-3-13-32-16-20;1-19-10-14-23(15-11-19)30-28(32)25-17-22(13-12-20(25)2)24-9-6-16-31-26(18-29-27(24)31)21-7-4-3-5-8-21;1-17-6-9-20(10-7-17)30-27(34)22-14-18(8-11-23(22)28)21-5-3-13-32-25(19-4-2-12-29-15-19)24(16-33)31-26(21)32/h3-16H,1-2H3,(H,34,36);3-18H,1-2H3,(H,30,32);2-15,33H,16H2,1H3,(H,30,34).
What are the key properties of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?
2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide has a molecular weight of 1372.95 g/mol, XLogP of 19.26, 13 rotatable bonds, 4 hydrogen bond donors, and 12 hydrogen bond acceptors.
Where does this data come from?
All data for 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide is sourced from PubChem (CID 163863897), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).