(2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide

C14H16F3NO3 — CID 164638481

IUPAC(2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide
SMILESCO[C@@H](C(=O)NC1CC(O)C1)c1ccccc1C(F)(F)F
InChIInChI=1S/C14H16F3NO3/c1-21-12(13(20)18-8-6-9(19)7-8)10-4-2-3-5-11(10)14(15,16)17/h2-5,8-9,12,19H,6-7H2,1H3,(H,18,20)/t8?,9?,12-/m1/s1
InChIKeySBROCBAZOQRIHN-SHVIVCPWSA-N
MW303.28 g/mol
LogP2.03
Rot. Bonds4

About (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide

(2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide (PubChem CID 164638481) has the molecular formula C14H16F3NO3 and a molecular weight of 303.28 g/mol. Its IUPAC name is (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide.

Molecular Properties

Compound Name(2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide
PubChem CID164638481
Molecular FormulaC14H16F3NO3
Molecular Weight303.28 g/mol
Exact Mass303.11
IUPAC Name(2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide
SMILESCO[C@@H](C(=O)NC1CC(O)C1)c1ccccc1C(F)(F)F
InChIInChI=1S/C14H16F3NO3/c1-21-12(13(20)18-8-6-9(19)7-8)10-4-2-3-5-11(10)14(15,16)17/h2-5,8-9,12,19H,6-7H2,1H3,(H,18,20)/t8?,9?,12-/m1/s1
InChIKeySBROCBAZOQRIHN-SHVIVCPWSA-N
XLogP2.03
TPSA58.56 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds4
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500303.28
LogP ≤ 52.03
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

[2-(Cyclohexylamino)-1-(2-fluorophenyl)-2-oxoethyl] acetate
CID 3230480
[2-(Cyclohexylamino)-1-(3-fluorophenyl)-2-oxoethyl] acetate
CID 3230481
N-cyclooctyl-2-methoxy-2-phenylacetamide
CID 2921709
N-cyclopropyl-2-methoxy-2-phenylacetamide
CID 3452814
N-(2,4-dimethylpentan-3-yl)-2-methoxy-2-phenylacetamide
CID 2897080
N-[(2R,4R)-1-hydroxy-4-methoxy-4-phenylbutan-2-yl]dodecanamide
CID 11810947
(2R)-2-methoxy-2-phenyl-N-(tetrahydro-2H-pyran-4-yl)acetamide
CID 50956380
N-[(R)-2-methoxy-2-(o-tolyl)ethyl]3-[p-(trifluoromethyl)phenyl]propionamide
CID 97417766
N-[2-(cyclohexen-1-yl)ethyl]-2-methoxy-2-phenylacetamide
CID 3837694
(2R)-3,3,3-trifluoro-2-methoxy-N-(4-oxotridecan-3-yl)-2-phenylpropanamide
CID 44216791
2,2,2-trifluoro-N-[(1S,2S)-1-[(3S)-1-hydroxy-3-methylhex-5-en-3-yl]oxy-1-phenylpropan-2-yl]acetamide
CID 101101357
(2R)-3,3,3-trifluoro-2-methoxy-N-[(2S,3E,5E)-6-[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]hexa-3,5-dien-2-yl]-2-phenylpropanamide
CID 139090762

Frequently Asked Questions

What is the IUPAC name of (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide?
The IUPAC name of (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide (CID 164638481) is (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide.
What is the SMILES notation for (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide?
The canonical SMILES for (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide is CO[C@@H](C(=O)NC1CC(O)C1)c1ccccc1C(F)(F)F.
What is the InChIKey of (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide?
The InChIKey is SBROCBAZOQRIHN-SHVIVCPWSA-N. The full InChI is InChI=1S/C14H16F3NO3/c1-21-12(13(20)18-8-6-9(19)7-8)10-4-2-3-5-11(10)14(15,16)17/h2-5,8-9,12,19H,6-7H2,1H3,(H,18,20)/t8?,9?,12-/m1/s1.
What are the key properties of (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide?
(2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide has a molecular weight of 303.28 g/mol, XLogP of 2.03, 4 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-N-(3-hydroxycyclobutyl)-2-methoxy-2-[2-(trifluoromethyl)phenyl]acetamide is sourced from PubChem (CID 164638481), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).