1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

C128H132Cl6N34O2S5 — CID 164968010

About 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (PubChem CID 164968010) has the molecular formula C128H132Cl6N34O2S5 and a molecular weight of 2551.75 g/mol. Its IUPAC name is 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

Molecular Properties

• Compound Name: 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• PubChem CID: 164968010
• Molecular Formula: C128H132Cl6N34O2S5
• Molecular Weight: 2551.75 g/mol
• Exact Mass: 2546.80
• IUPAC Name: 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• SMILES: Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2c(CO)cnc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1cccc(Cl)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1ccnc(NC2CC2)c1Cl.Cc1nc(N2CCC3(CC2)Oc2ccccc2C3N)n2ccnc2c1Sc1ccnc(N)c1Cl.Nc1nccc(Sc2c(N)nc(N3CCC4(CC3)Cc3ccccc3C4N)n3ccnc23)c1Cl
• InChI: InChI=1S/C28H30ClN7S.C26H25Cl2N5S.C26H28ClN7OS.C24H25ClN8S.C24H24ClN7OS/c1-17-23(37-21-8-11-31-25(22(21)29)34-19-6-7-19)26-32-12-15-36(26)27(33-17)35-13-9-28(10-14-35)16-18-4-2-3-5-20(18)24(28)30;1-16-22(34-20-8-4-7-19(27)21(20)28)24-30-11-14-33(24)25(31-16)32-12-9-26(10-13-32)15-17-5-2-3-6-18(17)23(26)29;1-15-21(36-19-6-9-30-23(29)20(19)27)24-31-13-17(14-35)34(24)25(32-15)33-10-7-26(8-11-33)12-16-4-2-3-5-18(16)22(26)28;25-17-16(5-8-29-20(17)27)34-18-21(28)31-23(33-12-9-30-22(18)33)32-10-6-24(7-11-32)13-14-3-1-2-4-15(14)19(24)26;1-14-19(34-17-6-9-28-21(27)18(17)25)22-29-10-13-32(22)23(30-14)31-11-7-24(8-12-31)20(26)15-4-2-3-5-16(15)33-24/h2-5,8,11-12,15,19,24H,6-7,9-10,13-14,16,30H2,1H3,(H,31,34);2-8,11,14,23H,9-10,12-13,15,29H2,1H3;2-6,9,13,22,35H,7-8,10-12,14,28H2,1H3,(H2,29,30);1-5,8-9,12,19H,6-7,10-11,13,26,28H2,(H2,27,29);2-6,9-10,13,20H,7-8,11-12,26H2,1H3,(H2,27,28)
• InChIKey: CSTTVXKZAPGORF-UHFFFAOYSA-N
• XLogP: 24.33
• TPSA: 494.38 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 41
• Rotatable Bonds: 18
• Heavy Atoms: 175
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2551.75
LogP ≤ 5	24.33
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	41

Frequently Asked Questions

What is the IUPAC name of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The IUPAC name of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (CID 164968010) is 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

What is the SMILES notation for 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The canonical SMILES for 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2c(CO)cnc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1cccc(Cl)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1ccnc(NC2CC2)c1Cl.Cc1nc(N2CCC3(CC2)Oc2ccccc2C3N)n2ccnc2c1Sc1ccnc(N)c1Cl.Nc1nccc(Sc2c(N)nc(N3CCC4(CC3)Cc3ccccc3C4N)n3ccnc23)c1Cl.

What is the InChIKey of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The InChIKey is CSTTVXKZAPGORF-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30ClN7S.C26H25Cl2N5S.C26H28ClN7OS.C24H25ClN8S.C24H24ClN7OS/c1-17-23(37-21-8-11-31-25(22(21)29)34-19-6-7-19)26-32-12-15-36(26)27(33-17)35-13-9-28(10-14-35)16-18-4-2-3-5-20(18)24(28)30;1-16-22(34-20-8-4-7-19(27)21(20)28)24-30-11-14-33(24)25(31-16)32-12-9-26(10-13-32)15-17-5-2-3-6-18(17)23(26)29;1-15-21(36-19-6-9-30-23(29)20(19)27)24-31-13-17(14-35)34(24)25(32-15)33-10-7-26(8-11-33)12-16-4-2-3-5-18(16)22(26)28;25-17-16(5-8-29-20(17)27)34-18-21(28)31-23(33-12-9-30-22(18)33)32-10-6-24(7-11-32)13-14-3-1-2-4-15(14)19(24)26;1-14-19(34-17-6-9-28-21(27)18(17)25)22-29-10-13-32(22)23(30-14)31-11-7-24(8-12-31)20(26)15-4-2-3-5-16(15)33-24/h2-5,8,11-12,15,19,24H,6-7,9-10,13-14,16,30H2,1H3,(H,31,34);2-8,11,14,23H,9-10,12-13,15,29H2,1H3;2-6,9,13,22,35H,7-8,10-12,14,28H2,1H3,(H2,29,30);1-5,8-9,12,19H,6-7,10-11,13,26,28H2,(H2,27,29);2-6,9-10,13,20H,7-8,11-12,26H2,1H3,(H2,27,28).

What are the key properties of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine has a molecular weight of 2551.75 g/mol, XLogP of 24.33, 18 rotatable bonds, 11 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylamino)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-(2,3-dichlorophenyl)sulfanyl-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is sourced from PubChem (CID 164968010), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).